Idioma:

Presence of Trypanosoma cruzi antigen on the surface of both infected and uninfected cells in tissue culture

Abrahamsohn, I. A. ; Kloetzel, J. K.

Parasitology, 1980-02, Vol.80 (1), p.147-152 [Periódico revisado por pares]

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Título:
Presence of Trypanosoma cruzi antigen on the surface of both infected and uninfected cells in tissue culture
Autor: Abrahamsohn, I. A. ; Kloetzel, J. K.
Assuntos: Animals ; Antigens - analysis ; Antigens, Surface - analysis ; Cell Line ; Cell Membrane - immunology ; Fluorescent Antibody Technique ; Haplorhini ; Kidney ; Macaca ; Trypanosoma cruzi - growth & development ; Trypanosoma cruzi - immunology
É parte de: Parasitology, 1980-02, Vol.80 (1), p.147-152
Notas: PII:S0031182000000603
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content type line 23
Descrição: LLC-MK2 cell monolayers infected with Trypanosoma cruzi were shown by immunofluorescence to present parasite antigens on the surface of both parasitized and non-parasitized cells after completion of the first intracellular cycle and rupture of infected cells. The cell-culture supernatant fluid at this stage, as well as the supernatant fluid of parasites left overnight in culture medium were concentrated and contained antigen capable of binding to uninfected cell monolayers. The origin of this antigen, as well as its eventual role in the pathogenesis of Chagas' disease, are discussed.
Editor: Cambridge, UK: Cambridge University Press
Idioma: Inglês

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