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High-Performance Liquid Chromatographic Analysis of Acidic Saponins of Ginseng and Related Plants

YAMAGUCHI, HIROYUKI ; KASAI, RYOJI ; MATSUURA, HIROMICHI ; TANAKA, OSAMU ; FUWA, TORU

Chemical and Pharmaceutical Bulletin, 1988/09/25, Vol.36(9), pp.3468-3473 [Periódico revisado por pares]

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High-Performance Liquid Chromatographic Analysis of Acidic Saponins of Ginseng and Related Plants
Autor: YAMAGUCHI, HIROYUKI ; KASAI, RYOJI ; MATSUURA, HIROMICHI ; TANAKA, OSAMU ; FUWA, TORU
Assuntos: Biological and medical sciences ; Chromatography, High Pressure Liquid ; Medical sciences ; Panax - analysis ; Pharmacology. Drug treatments ; Plants, Medicinal ; Sanchi-ginseng ; Saponins - analysis
É parte de: Chemical and Pharmaceutical Bulletin, 1988/09/25, Vol.36(9), pp.3468-3473
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: High-performance liquid chromatography (HPLC) of the glucuronide saponin (ginsenoside-Ro) and malonyl-saponins (malonyl-ginsenosides-Rb1, -Rb2, -Rc and -Rd) in ginseng root was investigated. Separation of these acidic saponins as well as the major neutral saponins could be achieved by HPLC either on an octadecyl silica column or on an amino column by using aqueous acetonitrile containing KH2PO4 (the former column) or H3PO4 (the latter column) as the mobile phase. By means of this procedure, the contents of acidic and neutral saponins of Panax ginseng, P. quinquefolium (American ginseng), P. japonicus collected in South Kyushu, P. notoginseng (Sanchiginseng) and Panax species collected at central Nepal were determined and compared.
Editor: Tokyo: The Pharmaceutical Society of Japan
Idioma: Inglês

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