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Biofilm and bacterial microrganisms in genito-urinary infections

Mazzoli, Sandra

Le infezioni in medicina, 2009-06, Vol.17 Suppl 1, p.3 [Peer Reviewed Journal]

Italy

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Title:
Biofilm and bacterial microrganisms in genito-urinary infections
Author: Mazzoli, Sandra
Subjects: Animals ; Anti-Bacterial Agents - pharmacokinetics ; Anti-Bacterial Agents - therapeutic use ; Biofilms - drug effects ; Drug Resistance, Microbial ; Female ; Female Urogenital Diseases - drug therapy ; Female Urogenital Diseases - microbiology ; Gram-Negative Bacteria - drug effects ; Gram-Negative Bacteria - pathogenicity ; Gram-Negative Bacteria - physiology ; Gram-Negative Bacterial Infections - drug therapy ; Gram-Negative Bacterial Infections - microbiology ; Gram-Positive Bacteria - drug effects ; Gram-Positive Bacteria - pathogenicity ; Gram-Positive Bacteria - physiology ; Gram-Positive Bacterial Infections - drug therapy ; Gram-Positive Bacterial Infections - microbiology ; Humans ; Male ; Male Urogenital Diseases - drug therapy ; Male Urogenital Diseases - microbiology ; Mice ; Urinary Tract Infections - drug therapy ; Urinary Tract Infections - microbiology ; Virulence
Is Part Of: Le infezioni in medicina, 2009-06, Vol.17 Suppl 1, p.3
Description: Biofilms represent a cohesive matrix of microrganisms and other cellular constituents that might be present in any natural environment. Microrganisms able to produce biofilms undergo a number of distinctive and typical phenomenon, such as adhesiveness on infected cellular surfaces that consequently becomes irreversible, so deeply changing the microrganisms physiological status. In addition, biofilms play a central role in consenting microrganisms to survive and subsequently to spread in the host, since exocellular matrix protects pathogen bacteria from antibodies and immunocompetent cells devoted to their destruction, and from antimicrobial agents. So, use of antimicrobials able to penetrate cellular membrane and to act into the cell has to be considered as essential in the treatment of infections that may possibly involve biofilm-producer microrganisms, considering their aggressive and virulent behaviour and their intrinsic bacterial resistance.
Publisher: Italy
Language: Italian

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Biofilm and bacterial microrganisms in genito-urinary infections

Mazzoli, Sandra

Italy

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