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Is dementia reversible in patients with neurocysticercosis?

Ramirez-Bermudez, J ; Higuera, J ; Sosa, A L ; Lopez-Meza, E ; Lopez-Gomez, M ; Corona, T

Journal of neurology, neurosurgery and psychiatry, 2005-08, Vol.76 (8), p.1164-1166 [Periódico revisado por pares]

London: BMJ Publishing Group Ltd

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Título:
Is dementia reversible in patients with neurocysticercosis?
Autor: Ramirez-Bermudez, J ; Higuera, J ; Sosa, A L ; Lopez-Meza, E ; Lopez-Gomez, M ; Corona, T
Assuntos: Adolescent ; Adult ; Aged ; Albendazole - therapeutic use ; Anthelmintics - therapeutic use ; Biological and medical sciences ; COGNISTAT ; Delirium Rating Scale ; Dementia ; Dementia - diagnosis ; Dementia - etiology ; Diagnostic and Statistical Manual of Mental Disorders ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; DRS ; Educational Status ; Female ; Frontal Lobe - parasitology ; Humans ; Informant Questionnaire on Cognitive Decline ; IQCODE ; Male ; Medical sciences ; Middle Aged ; Mini-mental State Examination ; MMSE ; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis ; NCC ; Nervous system (semeiology, syndromes) ; Neurobehavioral Cognitive Status Examination ; neurocysticercosis ; Neurocysticercosis - complications ; Neurocysticercosis - drug therapy ; Neurocysticercosis - parasitology ; Neurology ; neuropsychiatry ; Neuropsychological Tests ; Parietal Lobe - parasitology ; Severity of Illness Index ; Short Report ; Temporal Lobe - parasitology ; Treatment Outcome
É parte de: Journal of neurology, neurosurgery and psychiatry, 2005-08, Vol.76 (8), p.1164-1166
Notas: PMID:16024900
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istex:98FF6B05A67FC98F252B922E9BF26D763EC0F1CE
Correspondence to:  Dr T Corona  Department of Neurology, Instituto Nacional de Neurología y Neurocirugía. Insurgentes Sur 3877, La Fama 14269, México City, México; coronav@servidor.unam.mx
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Descrição: Objective: To determine the correlates and outcome of dementia in patients with neurocysticercosis (NCC). Methods: Ninety consecutive patients with untreated NCC underwent a cognitive assessment (Mini-mental State Examination, Neurobehavioral Cognitive Status Examination, and IQCODE) and were classified as having or not having dementia according to DSM-IV criteria. Imaging and cerebrospinal fluid examination data were recorded. The cognitive measures were repeated six months after treatment with albendazole and steroids. Results: At the initial evaluation 15.5% (n = 14) of the patients were classified as having dementia. Dementia was associated with older age, lower education level, increased number of parasitic lesions in the brain (mostly in the frontal, temporal, and parietal lobes). After six months, 21.5% of the patients from the dementia group continued to have a full dementia disorder and 78.5% no longer fulfilled the DSM-IV criteria for dementia, although some of these patients still showed mild cognitive decline. Conclusions: The results of this study suggest that dementia occurs frequently in patients with untreated NCC, and it is reversible in most cases.
Editor: London: BMJ Publishing Group Ltd
Idioma: Inglês

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Is dementia reversible in patients with neurocysticercosis?

Ramirez-Bermudez, J ; Higuera, J ; Sosa, A L ; Lopez-Meza, E ; Lopez-Gomez, M ; Corona, T

London: BMJ Publishing Group Ltd

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