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Kidney biopsy in the hepatosplenic form of infection with Schistosoma mansoni in man

da Silva, L C ; de Brito, T ; Camargo, M E ; de Boni, D R ; Lopes, J D ; Gunji, J

Bulletin of the World Health Organization, 1970, Vol.42 (6), p.907-910 [Periódico revisado por pares]

Switzerland

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  • Título:
    Kidney biopsy in the hepatosplenic form of infection with Schistosoma mansoni in man
  • Autor: da Silva, L C ; de Brito, T ; Camargo, M E ; de Boni, D R ; Lopes, J D ; Gunji, J
  • Assuntos: Biopsy ; Fluorescent Antibody Technique ; Humans ; Kidney - pathology ; Kidney Diseases - pathology ; Liver Diseases, Parasitic - pathology ; Microscopy, Electron ; Schistosomiasis - pathology ; Splenic Diseases - pathology
  • É parte de: Bulletin of the World Health Organization, 1970, Vol.42 (6), p.907-910
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
    From the Instituto de Medicina Tropical and the Hospital das Clinícas, University of São Paulo, Brazil. This work was supported by grants from the Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia and the Fundaçâo de Amparo à Pesquisa do Estado de São Paulo, and by grant No. DAHC 19-69-C-0014 from the US Army Research Office.
  • Descrição: A study of early glomerular lesions was made in 8 patients infected with Schistosoma mansoni but having no clinical evidence of renal disease. Electron-microscopy of renal biopsies showed the presence of electron-dense deposits in basement membranes and of laminated bodies near the mesangial cells. Immunofluorescence showed that the deposits corresponded to IgG in 8 cases and to IgM in 2 cases. These lesions are comparable with those found in the kidneys of patients with cirrhosis of the liver.
  • Editor: Switzerland
  • Idioma: Inglês

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