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Dyslipidaemia in hypertensive obese type 2 diabetic patients in Jamaica

Gordon, Lorenzo ; Ragoobirsingh, Dalip ; Morrison, Errol ; McGrowder, Donovan ; Choo-Kang, Eric ; Martorell, E

Archives of medical science, 2010-10, Vol.6 (5), p.701-708 [Periódico revisado por pares]

Poland: Termedia Publishing House

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  • Título:
    Dyslipidaemia in hypertensive obese type 2 diabetic patients in Jamaica
  • Autor: Gordon, Lorenzo ; Ragoobirsingh, Dalip ; Morrison, Errol ; McGrowder, Donovan ; Choo-Kang, Eric ; Martorell, E
  • Assuntos: Clinical Research
  • É parte de: Archives of medical science, 2010-10, Vol.6 (5), p.701-708
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: Hypertension and obesity are common problems among diabetic patients accelerating progression of vascular diabetic complications. A two-stage stratified random sampling design was used, and individuals aged 15 years and over were interviewed. This cross-sectional study evaluated lipid abnormalities of 117 obese type 2 diabetic patients (28 males and 89 females), and 56 hypertensive obese type 2 diabetic patients (22 males and 34 females). Total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C) and high-density lipoprotein cholesterol (HDL-C) concentrations were assayed using standard biochemical methods. Hypertensive obese type 2 diabetic females had significantly higher mean serum concentrations of TC (p = 0.043), TG (p = 0.046), LDL-C (p= 0.040), TC/HDL-C ratio (p = 0.001) and LDL-C/HDL-C ratio (p = 0.003) compared with hypertensive obese non-diabetic females. Similar results were found in hypertensive obese type 2 diabetic males compared with hypertensive obese non-diabetic males. Hypertensive obese type 2 diabetic females had significantly higher serum TC, TG and TC/HDL-C ratio (p < 0.05) than hypertensive obese type 2 diabetic males. Hypertensive obese type 2 diabetic females had significantly higher mean serum concentrations of TG (p = 0.03) and TC (p = 0.01) than obese type 2 diabetic females. There was a significant association between blood glucose and LDL-C concentrations in type 2 diabetic subjects (r = 0.36; p< 0.05). Obese hypertensive type 2 diabetic females are exposed more profoundly to risk factors including atherogenic dyslipidaemia compared with males.
  • Editor: Poland: Termedia Publishing House
  • Idioma: Inglês
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