1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia

Anandan, Sampath-Kumar ; Webb, Heather Kay ; Chen, Dawn ; Wang, Yi-Xin (Jim) ; Aavula, Basker R. ; Cases, Sylvaine ; Cheng, Ying ; Do, Zung N. ; Mehra, Upasana ; Tran, Vinh ; Vincelette, Jon ; Waszczuk, Joanna ; White, Kathy ; Wong, Kenneth R. ; Zhang, Le-Ning ; Jones, Paul D. ; Hammock, Bruce D. ; Patel, Dinesh V. ; Whitcomb, Randall ; MacIntyre, D. Euan ; Sabry, James ; Gless, Richard

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (3), p.983-988 [Peer Reviewed Journal]

Amsterdam: Elsevier Ltd

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