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Detection biomarkers of lung cancer using mini-GC-PID system integrated with micro GC column and micro pre-concentrator

Sun, Jianhai ; Cui, Dafu ; Guan, Fengying ; Zhang, Lulu ; Chen, Xing ; Li, Hui

Nanoscale research letters, 2014-10, Vol.9 (1), p.576-576, Article 576 [Revista revisada por pares]

New York: Springer New York

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  • Título:
    Detection biomarkers of lung cancer using mini-GC-PID system integrated with micro GC column and micro pre-concentrator
  • Autor: Sun, Jianhai ; Cui, Dafu ; Guan, Fengying ; Zhang, Lulu ; Chen, Xing ; Li, Hui
  • Materias: Chemistry and Materials Science ; Materials Science ; Molecular Medicine ; Nano Review ; Nanochemistry ; Nanoscale Science and Technology ; Nanotechnology ; Nanotechnology and Microengineering
  • Es parte de: Nanoscale research letters, 2014-10, Vol.9 (1), p.576-576, Article 576
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descripción: The survival rate of lung cancer can be significantly improved by monitoring biomarkers in exhaled air that indicate diseases in early stage, so it is very important to develop micro analytical systems which can offer a fast, on-site, real-time detecting biomarkers in exhaled air. In this paper, a mini-gas chromatography (GC)-photo-ionization detector (PID) system integrated with a micro GC column and a micro pre-concentrator was developed for forming an inexpensive, fast, and non-invasive diagnostic tool for lung cancer. This system has very strong concentrate ability owing to its integrated micro pre-concentrator, which make the detection of trace components in exhaled air very easy. In addition, the integrated micro GC column can separate complex mixtures, which overcome low resolution and poor anti-interference ability of other instruments. The results indicated that the mini-GC-PID system can effectively separate and detect the biomarkers at parts-per-billion (ppb) level.
  • Editor: New York: Springer New York
  • Idioma: Inglés
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