Idioma:

Trends in the incidence of diabetes, its clinical sequelae, and associated costs in pregnancy

Jovanovič, Lois ; Liang, Yuanjie ; Weng, Wayne ; Hamilton, Marianthe ; Chen, Lisa ; Wintfeld, Neil

Diabetes/metabolism research and reviews, 2015-10, Vol.31 (7), p.707-716 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

Texto completo disponível

Citações Citado por

Enviar para

Título:
Trends in the incidence of diabetes, its clinical sequelae, and associated costs in pregnancy
Autor: Jovanovič, Lois ; Liang, Yuanjie ; Weng, Wayne ; Hamilton, Marianthe ; Chen, Lisa ; Wintfeld, Neil
Assuntos: Abortion, Spontaneous - economics ; Abortion, Spontaneous - epidemiology ; Adolescent ; Adult ; Anemia - economics ; Anemia - epidemiology ; Cesarean Section - economics ; Cesarean Section - statistics & numerical data ; Congenital Abnormalities - economics ; Congenital Abnormalities - epidemiology ; cost-effectiveness ; Depression - economics ; Depression - epidemiology ; Diabetes ; diabetes complications ; Diabetes Mellitus, Type 1 - economics ; Diabetes Mellitus, Type 1 - epidemiology ; Diabetes Mellitus, Type 2 - economics ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes, Gestational - economics ; Diabetes, Gestational - epidemiology ; Female ; gestational diabetes ; Health Care Costs ; Heart Defects, Congenital - economics ; Heart Defects, Congenital - epidemiology ; Humans ; Incidence ; Infant, Newborn ; Middle Aged ; Pregnancy ; Pregnancy Complications, Cardiovascular - economics ; Pregnancy Complications, Cardiovascular - epidemiology ; Pregnancy Complications, Hematologic - economics ; Pregnancy Complications, Hematologic - epidemiology ; Pregnancy Complications, Infectious - economics ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy in Diabetics - economics ; Pregnancy in Diabetics - epidemiology ; Pregnancy Outcome - economics ; Pregnancy Outcome - epidemiology ; Retrospective Studies ; Stillbirth - economics ; Stillbirth - epidemiology ; type 1 diabetes ; type 2 diabetes ; United States ; Young Adult
É parte de: Diabetes/metabolism research and reviews, 2015-10, Vol.31 (7), p.707-716
Notas: Supporting info item
ark:/67375/WNG-RL1J938B-T
Novo Nordisk Inc.
istex:47D86E012FF9594EF9A79858BD674228E5CAB1EB
ArticleID:DMRR2656
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Background Increasing diabetes prevalence affects a substantial number of pregnant women in the United States. Our aims were to evaluate health outcomes, medical costs, risks and types of complications associated with diabetes in pregnancy for mothers and newborns. Methods In this retrospective claims analysis, patients were identified from the Truven Health MarketScan® database (2004–2011 inclusive). Participants were aged 18–45 years, with ascertainable diabetes status [Yes/No], date of birth event >2005 and continuous health plan enrolment ≥21 months before and 3 months after the birth. Results In total, 839 792 pregnancies were identified, and 66 041 (7.86%) were associated with diabetes mellitus [type 1 (T1DM), 0.13%; type 2 (T2DM), 1.21%; gestational (GDM), 6.29%; and GDM progressing to T2DM (patients without prior diabetes who had a T2DM diagnosis after the birth event), 0.23%]. Relative risk (RR) of stillbirth (2.51), miscarriage (1.28) and Caesarean section (C‐section) (1.77) was significantly greater with T2DM versus non‐diabetes. Risk of C‐section was also significantly greater for other diabetes types [RR 1.92 (T1DM); 1.37 (GDM); 1.63 (GDM progressing to T2DM)]. Risk of overall major congenital (RR ≥ 1.17), major congenital circulatory (RR ≥ 1.19) or major congenital heart (RR ≥ 1.18) complications was greater in newborns of mothers with diabetes versus without. Mothers with T2DM had significantly higher risk (RR ≥ 1.36) of anaemia, depression, hypertension, infection, migraine, or cardiac, obstetrical or respiratory complications than non‐diabetes patients. Mean medical costs were higher with all diabetes types, particularly T1DM ($27 531), than non‐diabetes ($14 355). Conclusions Complications and costs of healthcare were greater with diabetes, highlighting the need to optimize diabetes management in pregnancy. © 2015 The Authors. Diabetes/Metabolism Research and Reviews published by John Wiley & Sons, Ltd.
Editor: England: Blackwell Publishing Ltd
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Trends in the incidence of diabetes, its clinical sequelae, and associated costs in pregnancy

Jovanovič, Lois ; Liang, Yuanjie ; Weng, Wayne ; Hamilton, Marianthe ; Chen, Lisa ; Wintfeld, Neil

England: Blackwell Publishing Ltd

Buscando em bases de dados remotas. Favor aguardar.