Language:

A digital 3D atlas of the marmoset brain based on multi-modal MRI

Liu, Cirong ; Ye, Frank Q. ; Yen, Cecil Chern-Chyi ; Newman, John D. ; Glen, Daniel ; Leopold, David A. ; Silva, Afonso C.

NeuroImage (Orlando, Fla.), 2018-04, Vol.169, p.106-116 [Peer Reviewed Journal]

United States: Elsevier Inc

Full text available

Citations Cited by

Actions
1. Add to e-Shelf
2. Remove from e-Shelf
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
A digital 3D atlas of the marmoset brain based on multi-modal MRI
Author: Liu, Cirong ; Ye, Frank Q. ; Yen, Cecil Chern-Chyi ; Newman, John D. ; Glen, Daniel ; Leopold, David A. ; Silva, Afonso C.
Subjects: AFNI ; Animals ; Atlases as Topic ; Brain - anatomy & histology ; Brain - diagnostic imaging ; Brain architecture ; Brain mapping ; Brain research ; Callithrix - anatomy & histology ; Callithrix jacchus ; Cerebral Cortex - anatomy & histology ; Cerebral Cortex - diagnostic imaging ; Cortex ; Data processing ; Diffusion Magnetic Resonance Imaging - methods ; Diffusion MRI ; Female ; Functional magnetic resonance imaging ; Functional morphology ; Gene expression ; Histology ; Image processing ; Magnetic Resonance Imaging - methods ; Male ; Medical imaging ; Nervous system ; Neural networks ; Neuroimaging ; Neuroimaging - methods ; Neurosciences ; NMR ; Non-human primate ; Nuclear magnetic resonance ; Parcellation ; Software ; Template ; Usability
Is Part Of: NeuroImage (Orlando, Fla.), 2018-04, Vol.169, p.106-116
Notes: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Description: The common marmoset (Callithrix jacchus) is a New-World monkey of growing interest in neuroscience. Magnetic resonance imaging (MRI) is an essential tool to unveil the anatomical and functional organization of the marmoset brain. To facilitate identification of regions of interest, it is desirable to register MR images to an atlas of the brain. However, currently available atlases of the marmoset brain are mainly based on 2D histological data, which are difficult to apply to 3D imaging techniques. Here, we constructed a 3D digital atlas based on high-resolution ex-vivo MRI images, including magnetization transfer ratio (a T1-like contrast), T2w images, and multi-shell diffusion MRI. Based on the multi-modal MRI images, we manually delineated 54 cortical areas and 16 subcortical regions on one hemisphere of the brain (the core version). The 54 cortical areas were merged into 13 larger cortical regions according to their locations to yield a coarse version of the atlas, and also parcellated into 106 sub-regions using a connectivity-based parcellation method to produce a refined atlas. Finally, we compared the new atlas set with existing histology atlases and demonstrated its applications in connectome studies, and in resting state and stimulus-based fMRI. The atlas set has been integrated into the widely-distributed neuroimaging data analysis software AFNI and SUMA, providing a readily usable multi-modal template space with multi-level anatomical labels (including labels from the Paxinos atlas) that can facilitate various neuroimaging studies of marmosets. [Display omitted] •MRI-based 3D digital atlas of the marmoset brain for MRI and connectome studies.•Marmoset brain templates created from multi-modal high-resolution 3D MRI.•Anatomical regions manually delineated and labeled directly on MRI dataset.•Finer parcellation of the cortex obtained based on structural connectivity profiles.•Fully-featured atlas functions and integration with the Paxinos atlas.
Publisher: United States: Elsevier Inc
Language: English

Links

View this record in MEDLINE/PubMed

Back to results list

Previous Result 4 Next Go to Next page

Implemented by: Social Network Logos:

A digital 3D atlas of the marmoset brain based on multi-modal MRI

Liu, Cirong ; Ye, Frank Q. ; Yen, Cecil Chern-Chyi ; Newman, John D. ; Glen, Daniel ; Leopold, David A. ; Silva, Afonso C.

United States: Elsevier Inc

Searching Remote Databases, Please Wait