Idioma:

Epidemiology and Etiology of Invasive Bacterial Infection in Infants ≤60 Days Old Treated in Emergency Departments

Woll, Christopher ; Neuman, Mark I. ; Pruitt, Christopher M. ; Wang, Marie E. ; Shapiro, Eugene D. ; Shah, Samir S. ; McCulloh, Russell J. ; Nigrovic, Lise E. ; Desai, Sanyukta ; DePorre, Adrienne G. ; Leazer, Rianna C. ; Marble, Richard D. ; Balamuth, Fran ; Feldman, Elana A. ; Sartori, Laura F. ; Browning, Whitney L. ; Aronson, Paul L. ; Alpern, Elizabeth R. ; Hayes, Katie L. ; Lee, Brian R. ; Lumb, Catherine E. ; Mitchell, Christine E. ; Peaper, David R. ; Rooholamini, Sahar N. ; Shin, Sarah J. ; Williams, Derek J.

The Journal of pediatrics, 2018-09, Vol.200, p.210-217.e1 [Periódico revisado por pares]

United States: Elsevier Inc

Texto completo disponível

Citações Citado por

Enviar para

Título:
Epidemiology and Etiology of Invasive Bacterial Infection in Infants ≤60 Days Old Treated in Emergency Departments
Autor: Woll, Christopher ; Neuman, Mark I. ; Pruitt, Christopher M. ; Wang, Marie E. ; Shapiro, Eugene D. ; Shah, Samir S. ; McCulloh, Russell J. ; Nigrovic, Lise E. ; Desai, Sanyukta ; DePorre, Adrienne G. ; Leazer, Rianna C. ; Marble, Richard D. ; Balamuth, Fran ; Feldman, Elana A. ; Sartori, Laura F. ; Browning, Whitney L. ; Aronson, Paul L. ; Alpern, Elizabeth R. ; Hayes, Katie L. ; Lee, Brian R. ; Lumb, Catherine E. ; Mitchell, Christine E. ; Peaper, David R. ; Rooholamini, Sahar N. ; Shin, Sarah J. ; Williams, Derek J.
Assuntos: Anti-Bacterial Agents - therapeutic use ; bacteremia ; Bacteria - isolation & purification ; Bacterial Infections - drug therapy ; Bacterial Infections - epidemiology ; Bacterial Infections - microbiology ; Cross-Sectional Studies ; Emergency Service, Hospital ; febrile infant ; Female ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; meningitis ; pathogen ; Retrospective Studies ; United States - epidemiology
É parte de: The Journal of pediatrics, 2018-09, Vol.200, p.210-217.e1
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Current affiliation is Lucile Packard Children’s Hospital Stanford, Palo Alto, CA
Descrição: To help guide empiric treatment of infants ≤60 days old with suspected invasive bacterial infection by describing pathogens and their antimicrobial susceptibilities. Cross-sectional study of infants ≤60 days old with invasive bacterial infection (bacteremia and/or bacterial meningitis) evaluated in the emergency departments of 11 children's hospitals between July 1, 2011 and June 30, 2016. Each site's microbiology laboratory database or electronic medical record system was queried to identify infants from whom a bacterial pathogen was isolated from either blood or cerebrospinal fluid. Medical records of these infants were reviewed to confirm the presence of a pathogen and to obtain demographic, clinical, and laboratory data. Of the 442 infants with invasive bacterial infection, 353 (79.9%) had bacteremia without meningitis, 64 (14.5%) had bacterial meningitis with bacteremia, and 25 (5.7%) had bacterial meningitis without bacteremia. The peak number of cases of invasive bacterial infection occurred in the second week of life; 364 (82.4%) infants were febrile. Group B streptococcus was the most common pathogen identified (36.7%), followed by Escherichia coli (30.8%), Staphylococcus aureus (9.7%), and Enterococcus spp (6.6%). Overall, 96.8% of pathogens were susceptible to ampicillin plus a third-generation cephalosporin, 96.0% to ampicillin plus gentamicin, and 89.2% to third-generation cephalosporins alone. For most infants ≤60 days old evaluated in a pediatric emergency department for suspected invasive bacterial infection, the combination of ampicillin plus either gentamicin or a third-generation cephalosporin is an appropriate empiric antimicrobial treatment regimen. Of the pathogens isolated from infants with invasive bacterial infection, 11% were resistant to third-generation cephalosporins alone.
Editor: United States: Elsevier Inc
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Anterior Resultado 4 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Epidemiology and Etiology of Invasive Bacterial Infection in Infants ≤60 Days Old Treated in Emergency Departments

United States: Elsevier Inc

Buscando em bases de dados remotas. Favor aguardar.