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Virtual Boot Camp: COVID‐19 evolution and structural biology

Burley, Stephen K. ; Bromberg, Yana ; Craig, Paul ; Duffy, Siobain ; Dutta, Shuchismita ; Hall, Bonnie L. ; Hudson, Brian P. ; Jiang, Jennifer ; Khare, Sagar ; Koeppe, Julia R. ; Lubin, Joseph H. ; Mills, Stephen A. ; Pikaart, Michael J. ; Roberts, Rebecca ; Sarma, Vidur ; Singh, Jitendra ; Tischfield, Jay A. ; Xie, Lingjun ; Zardecki, Christine

Biochemistry and molecular biology education, 2020-09, Vol.48 (5), p.511-513 [Periódico revisado por pares]

Hoboken, USA: John Wiley & Sons, Inc

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Título:
Virtual Boot Camp: COVID‐19 evolution and structural biology
Autor: Burley, Stephen K. ; Bromberg, Yana ; Craig, Paul ; Duffy, Siobain ; Dutta, Shuchismita ; Hall, Bonnie L. ; Hudson, Brian P. ; Jiang, Jennifer ; Khare, Sagar ; Koeppe, Julia R. ; Lubin, Joseph H. ; Mills, Stephen A. ; Pikaart, Michael J. ; Roberts, Rebecca ; Sarma, Vidur ; Singh, Jitendra ; Tischfield, Jay A. ; Xie, Lingjun ; Zardecki, Christine
Assuntos: 60 APPLIED LIFE SCIENCES ; biochemistry & molecular biology ; Computational Biology - education ; Coronavirus 3C Proteases - chemistry ; Coronavirus 3C Proteases - genetics ; COVID-19 ; COVID-19 - epidemiology ; Curriculum ; education & educational research ; Education, Distance ; Evolution, Molecular ; Humans ; Pandemics ; SARS-CoV-2 - chemistry ; SARS-CoV-2 - genetics
É parte de: Biochemistry and molecular biology education, 2020-09, Vol.48 (5), p.511-513
Notas: Funding information
National Institutes of Health, Grant/Award Numbers: R01GM133198, T32 GM008339; National Science Foundation, Grant/Award Numbers: DBI‐1832184, IUSE 1709170, 1709355, 1709805, 1709278; US Department of Energy, Grant/Award Number: DE‐SC0019749
ObjectType-Article-1
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National Cancer Institute (NCI)
USDOE Office of Science (SC)
National Science Foundation (NSF)
DE‐SC0019749; SC0019749; DBI-1832184; R01GM133198; IUSE 1709170; 1709355; 1709805; 1709278; NIH T32 GM008339
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
Funding information National Institutes of Health, Grant/Award Numbers: R01GM133198, T32 GM008339; National Science Foundation, Grant/Award Numbers: DBI‐1832184, IUSE 1709170, 1709355, 1709805, 1709278; US Department of Energy, Grant/Award Number: DE‐SC0019749
Descrição: COVID-19-related campus closures necessitated invention of an intensive online learning experience that introduced students to Structural Bioinformatics. The program engaged 33 students from 11 different institutions ranging from high school to graduate school. The objectives of the intensive, 1-week Boot Camp focused on helping students build a foundation for studying the SARS-CoV-2 Main Protease (Nsp5) to understand how the protein evolved during the first 6 months of the COVID-19 pandemic by exploring amino acid sequence and 3D atomic-level structure using various structural bioinformatics tools. Participants analyzed how the protein changed as the virus spread around the world, comparing Nsp5 from the original viral isolate to 161 unique sequence/structure variants.
Editor: Hoboken, USA: John Wiley & Sons, Inc
Idioma: Inglês

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Virtual Boot Camp: COVID‐19 evolution and structural biology

Hoboken, USA: John Wiley & Sons, Inc

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