Idioma:

Early-life risk factors and incidence of rhinitis: Results from the European Community Respiratory Health Study—an international population-based cohort study

Matheson, Melanie Claire, BSc, MAppSc, PhD ; Dharmage, Shyamali Chandrika, MBBS, MSc, MD, PhD ; Abramson, Michael John, MBBS, BMedSc(Hons), FRACP, PhD ; Walters, Eugene Haydn, MA, DM, FRCP, FRACP ; Sunyer, Jordi, MD, PhD ; de Marco, Roberto, PhD ; Leynaert, Benedicte, MSc, PhD ; Heinrich, Joachim, PhD ; Jarvis, Deborah, MD ; Norbäck, Dan, PhD ; Raherison, Chantal, MD, PhD ; Wjst, Matthias, MD, PhD ; Svanes, Cecilie, MD, PhD

Journal of allergy and clinical immunology, 2011-10, Vol.128 (4), p.816-823.e5 [Periódico revisado por pares]

New York, NY: Mosby, Inc

Texto completo disponível

Citações Citado por

Enviar para

Título:
Early-life risk factors and incidence of rhinitis: Results from the European Community Respiratory Health Study—an international population-based cohort study
Autor: Matheson, Melanie Claire, BSc, MAppSc, PhD ; Dharmage, Shyamali Chandrika, MBBS, MSc, MD, PhD ; Abramson, Michael John, MBBS, BMedSc(Hons), FRACP, PhD ; Walters, Eugene Haydn, MA, DM, FRCP, FRACP ; Sunyer, Jordi, MD, PhD ; de Marco, Roberto, PhD ; Leynaert, Benedicte, MSc, PhD ; Heinrich, Joachim, PhD ; Jarvis, Deborah, MD ; Norbäck, Dan, PhD ; Raherison, Chantal, MD, PhD ; Wjst, Matthias, MD, PhD ; Svanes, Cecilie, MD, PhD
Assuntos: Adolescence ; Adult ; Age ; Allergies ; Allergy and Immunology ; Atopy ; Biological and medical sciences ; Child ; Child, Preschool ; Children ; Cohort Studies ; Disease ; Dose-response effects ; Environmental Exposure ; European Union ; farming lifestyle ; Farms ; Female ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; gender ; Health care ; Humans ; Hypotheses ; Immunopathology ; Infections ; Inventories ; Male ; Medical sciences ; Non tumoral diseases ; Otorhinolaryngology. Stomatology ; pet exposure ; Pets ; Pregnancy ; Rhinitis ; Rhinitis - epidemiology ; Rhinitis - etiology ; Risk Factors ; Rural Population ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; Sex Factors ; Siblings ; Statistical methods ; Studies ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
É parte de: Journal of allergy and clinical immunology, 2011-10, Vol.128 (4), p.816-823.e5
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
Descrição: Background Rhinitis is an increasingly common condition with a heavy health care burden, but relatively little is known about its risk factors. Objective To examine the association between early-life factors and the development of rhinitis in the European Community Respiratory Health Study (ECRHS). Methods In 1992-1994, community-based samples of 20-44-year-old people were recruited from 48 centers in 22 countries. On average, 8.9 years later, 28 centers reinvestigated their samples. Onset of rhinitis was reported by 8486 participants in interviewer-led questionnaires. Cox regression was used to assess independent predictors of rhinitis at ages ≤5, 6-10, 11-20, and ≥21 years. Results The crude lifelong incidence of rhinitis was 7.00/1000/year (men) and 7.95/1000/year (women) ( P = .002). Women developed less rhinitis in later childhood (hazard ratios [HR], 0.63; 95% CI, 0.47-0.85) and more rhinitis in adulthood (HR, 1.36; 95% CI, 1.11-1.66) than did men. In atopic subjects, siblings were associated with lower risk of rhinitis throughout life (pooled HR, 0.94; 95% CI, 0.91-0.98 per 1 sibling). Early contact with children in the family or day care was associated with less incidence of rhinitis, predominantly before age 5 years (HR, 0.84; 95% CI, 0.72-0.99). Early childhood pets or growing up on a farm was associated with less incidence of rhinitis in adolescence (HR, 0.50; 95% CI, 0.37-0.68). Combining these factors showed evidence of a dose-response relationship (trend P = .0001). Conclusions Gender is a strong risk factor for rhinitis, with age patterns varying according to atopic status. Protective effects of early contact with children and animals were suggested for incident rhinitis, with risk patterns varying by age window and atopic status.
Editor: New York, NY: Mosby, Inc
Idioma: Inglês

Links

Voltar para lista de resultados

Anterior Resultado 7 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Early-life risk factors and incidence of rhinitis: Results from the European Community Respiratory Health Study—an international population-based cohort study

New York, NY: Mosby, Inc

Buscando em bases de dados remotas. Favor aguardar.