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Cryopreservation and autotransplantation of human ovarian tissue prior to cytotoxic therapy – A technique in its infancy but already successful in fertility preservation

von Wolff, Michael ; Donnez, Jacques ; Hovatta, Outi ; Keros, Victoria ; Maltaris, Theodoris ; Montag, Markus ; Salle, Bruno ; Sonmezer, Murat ; Andersen, Claus Yding

European Journal of Cancer, 2009-06, Vol.45 (9), p.1547-1553 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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Título:
Cryopreservation and autotransplantation of human ovarian tissue prior to cytotoxic therapy – A technique in its infancy but already successful in fertility preservation
Autor: von Wolff, Michael ; Donnez, Jacques ; Hovatta, Outi ; Keros, Victoria ; Maltaris, Theodoris ; Montag, Markus ; Salle, Bruno ; Sonmezer, Murat ; Andersen, Claus Yding
Assuntos: Adult ; Antineoplastic Agents - adverse effects ; Biological and medical sciences ; Chemotherapy ; Cryopreservation ; Cryopreservation - methods ; Female ; Fertility ; Hematology, Oncology and Palliative Medicine ; Humans ; Infertility ; Medical sciences ; Medicin och hälsovetenskap ; Neoplasm ; Ovarian Neoplasms - prevention & control ; Ovarian Neoplasms - secondary ; Ovary ; Ovary - transplantation ; Pharmacology. Drug treatments ; Primary Ovarian Insufficiency - chemically induced ; Primary Ovarian Insufficiency - surgery ; Radiotherapy ; Tissue Banks ; Transplantation ; Tumors
É parte de: European Journal of Cancer, 2009-06, Vol.45 (9), p.1547-1553
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Abstract Increasing survival rates in young cancer patients, new reproductive techniques and the growing interest in quality of life after gonadotoxic cancer therapies have placed fertility preservation as an important issue to oncologists, fertility specialists and patients. Several techniques are now available for fertility preservation in these patients. A new promising method is cryopreservation and transplantation of ovarian cortex. Ovarian tissue can be extracted by laparoscopy without any significant delay of gonadotoxic therapy. The tissue can be cryopreserved by specialised centres of reproductive medicine and transplanted in case the women experience premature ovarian failure (POF). This review summarises the European expertise on cryopreservation and transplantation of ovarian tissue, following around 30 reported transplantations globally, resulting in six live births and several ongoing pregnancies. It emphasises that fertility preservation by the cryopreservation of ovarian tissue is a new but already a successful clinical option, which can be considered for selected cancer patients.
Editor: Kidlington: Elsevier Ltd
Idioma: Inglês

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Cryopreservation and autotransplantation of human ovarian tissue prior to cytotoxic therapy – A technique in its infancy but already successful in fertility preservation

von Wolff, Michael ; Donnez, Jacques ; Hovatta, Outi ; Keros, Victoria ; Maltaris, Theodoris ; Montag, Markus ; Salle, Bruno ; Sonmezer, Murat ; Andersen, Claus Yding

Kidlington: Elsevier Ltd

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