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Effectiveness of Multimodal Treatment for Young People With Body Dysmorphic Disorder in Two Specialist Clinics

Rautio, Daniel ; Gumpert, Martina ; Jassi, Amita ; Krebs, Georgina ; Flygare, Oskar ; Andrén, Per ; Monzani, Benedetta ; Peile, Lauren ; Jansson-Fröjmark, Markus ; Lundgren, Tobias ; Hillborg, Maria ; Silverberg-Mörse, Maria ; Clark, Bruce ; Fernández de la Cruz, Lorena ; Mataix-Cols, David

Behavior therapy, 2022-09, Vol.53 (5), p.1037-1049 [Periódico revisado por pares]

Elsevier Ltd

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  • Título:
    Effectiveness of Multimodal Treatment for Young People With Body Dysmorphic Disorder in Two Specialist Clinics
  • Autor: Rautio, Daniel ; Gumpert, Martina ; Jassi, Amita ; Krebs, Georgina ; Flygare, Oskar ; Andrén, Per ; Monzani, Benedetta ; Peile, Lauren ; Jansson-Fröjmark, Markus ; Lundgren, Tobias ; Hillborg, Maria ; Silverberg-Mörse, Maria ; Clark, Bruce ; Fernández de la Cruz, Lorena ; Mataix-Cols, David
  • Assuntos: adolescents ; body dysmorphic disorder ; cognitive-behavior therapy ; dysmorphophobia ; Medicin och hälsovetenskap ; treatment outcomes
  • É parte de: Behavior therapy, 2022-09, Vol.53 (5), p.1037-1049
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
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  • Descrição: •The largest effectiveness study of young people with BDD to date.•CBT delivered flexibly, in combination with SSRIs, is effective for adolescent BDD.•Treatment gains were maintained up to 1 year after treatment.•BDD symptoms continued to improve throughout the follow-up.•No consistent baseline predictors of BDD treatment outcome were identified. Body dysmorphic disorder (BDD) typically originates in adolescence and is associated with considerable adversity. Evidence-based treatments exist but research on clinical outcomes in naturalistic settings is extremely scarce. We evaluated the short- and long-term outcomes of a large cohort of adolescents with BDD receiving specialist multimodal treatment and examined predictors of symptom improvement. We followed 140 young people (age range 10–18) with a diagnosis of BDD treated at two national and specialist outpatient clinics in Stockholm, Sweden (n = 96) and London, England (n = 44), between January 2015 and April 2021. Participants received multimodal treatment consisting of cognitive behavior therapy and, in 72% of cases, medication (primarily selective serotonin reuptake inhibitors). Data were collected at baseline, posttreatment, and 3, 6, and 12 months after treatment.The primary outcome measure was the clinician-rated Yale-Brown Obsessive-Compulsive Scale Modified for BDD, Adolescent version (BDD-YBOCS-A). Secondary outcomes included self-reported measures of BDD symptoms, depressive symptoms, and global functioning. Mixed-effects regression models showed that BDD-YBOCS-A scores decreased significantly from baseline to posttreatment (coefficient [95% confidence interval] = -16.33 [-17.90 to -14.76], p<0.001; within-group effect size (Cohen’s d) = 2.08 (95% confidence interval, 1.81 to 2.35). At the end of the treatment, 79% of the participants were classified as responders and 59% as full or partial remitters. BDD symptoms continued to improve throughout the follow-up. Improvement was also seen on all secondary outcome measures. Linear regression models identified baseline BDD symptom severity as a predictor of treatment outcome at posttreatment, but no consistent predictors were found at the 12-month follow-up. To conclude, multimodal treatment for adolescent BDD is effective in both the short- and long-term when provided flexibly within a specialist setting. Considering the high personal and societal costs of BDD, specialist care should be made more widely available.
  • Editor: Elsevier Ltd
  • Idioma: Inglês

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