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Gene therapy of cancer translational approaches from preclinical studies to clinical implementation

Edmund C Lattime 1951-; Stanton L Gerson

San Diego Academic Press c1999

Localização: FFCLRP - Fac. Fil. Ciên. Let. de R. Preto    (616-006.6 L364g ) e outros locais(Acessar)

  • Título:
    Gene therapy of cancer translational approaches from preclinical studies to clinical implementation
  • Autor: Edmund C Lattime 1951-; Stanton L Gerson
  • Assuntos: Cancer -- Gene therapy; Gene therapy; Cancer -- Immunotherapy; NEOPLASIAS; Neoplasms -- therapy; Gene Therapy -- methods; Immunotherapy -- methods; Neoplasms -- genetics
  • Notas: Includes bibliographical references and index
  • Descrição: Tumor suppressor genes as targets for cancer gene therapy -- Characterization of specific genetic alterations in cancer cells -- Immunologic targets for the gene therapy of cancer -- Retroviral vector design for cancer gene the rapy -- Non-infectious gene transfer and expression systems for cancer gene therapy -- Parvovirus vectors for the gene therapy of cancer -- Antibody-targeted gene therapy -- The Use of vaccinia virus vectors for immunotherapy v ia in situ tumor transfection -- Ribozymes in cancer gene therapy -- In situ use of suicide genes for cancer therapy -- Transfer of drug resistance genes into hematopoietic progenitors -- Cytosine deaminase as a suicide gene in cancer gene therapy -- Preemptive and therapeutic uses of suicide genes for cancer and leukemia -- Antisense strategies in the treatment of leukemias -- Selectively replicating viruses as therapeutic agents against cancer -- r as oncogene products as tumor-specific antigens for activation of T-lymphocyte-mediated immunity -- Polynucleotide-mediated immunization therapy of cancer -- DNA and dendritic cell-based genetic immunization against cancer -- E ngineering cellular cancer vaccines: gene and protein transfer options -- Cancer gene therapy by direct transfer of plasmid DNA in cationic lipids -- Ex vivo and in vivo cytoreductive gene therapy for urologic cancers: translat ion of molecular pharmacology to clinical pharmacology -- Applications of gene transfer in the adoptive
    immunotherapy of cancer -- Cytokine gene therapy of cancer -- The Use of genetically modified hematopoietic stem cells for cancer therapy -- Novel artificial tumor-specific killer cell and intrabody approaches for cancer therapy
  • Editor: San Diego Academic Press
  • Data de criação/publicação: c1999
  • Formato: xvii, 406 p., [8] p. of plates ill. (some col.) 29 cm..
  • Idioma: Inglês

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