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Cytochrome P450 protocols

Ian R Phillips (Ian Randall) 1951-; Elizabeth A Shephard (Elizabeth Anne) 1950-; Paul R Ortiz de Montellano

Totowa, N.J Humana London Springer distributor 2013

Localização: CQ - Conjunto das Químicas    (574.874 C9971 2013 )(Acessar)

  • Título:
    Cytochrome P450 protocols
  • Autor: Ian R Phillips (Ian Randall) 1951-; Elizabeth A Shephard (Elizabeth Anne) 1950-; Paul R Ortiz de Montellano
  • Assuntos: Cytochrome P-450; Cytochrome P-450 -- Laboratory manuals; Cytochrome P-450 Enzyme System; CITOCROMO P-450
  • Notas: Includes bibliographical references and index
  • Descrição: Bioluminescent assays for cytochrome P450 enzymes / Douglas S. Auld, Henrike Veith, and James J. Cali -- Simultaneous determination of multiple CYP inhibition constants using a cocktail-probe approach / Michael Zientek and Kuresh Youdim -- High-throughput mass spectrometric cytochrome P450 inhibition screening / Kheng B. Lim, Can C. Ozbal, and Daniel B. Kassel -- Synthesis, characterization, and application of ¹³c-methyl isocyanide as an NMR probe of heme protein active sites / Christopher McCullough ... [et al.] -- High-throughput fluorescence assay for cytochrome P450 mechanism-based Inactivators / Cesar Kenaan, Haoming Zhang, and Paul F. Hollenberg -- Identification of endogenous substrates of orphan cytochrome P450 enzymes through the use of untargeted metabolomics approaches / Qian Cheng and F. Peter Guengerich -- Genetic and mass spectrometric tools for elucidating the physiological function(s) of cytochrome P450 enzymes from Mycobacterium tuberculosis / Hugues Ouellet ... [et al.] -- Escherichia coli expression-based approach for porphyrin substitution in heme proteins / Michael B. Winter, Joshua J. Woodward, and Michael A. Marletta -- Expression in Escherichia coli of a cytochrome P450 enzyme with a cobalt protoporphyrin IX porosthetic group / Wesley E. Straub ... [et al.] -- Nanodiscs in the studies of membrane-bound cytochrome P450 enzymes / A. Luthra ... [et al.] -- Rapid LC-MS drug metabolite profiling using bioreactor particles / Linlin Zhao, Besnik Bajrami, and James F. Rusling -- Fluorescence-based screening of cytochrome P450 activities in intact cells / M. Teresa Donato and M. José Gómez-Lechón -- Screening for cytochrome P450 reactivity with a reporter enzyme / Kersten S. Rabe and Christof M. Niemeyer -- High-throughput fluorescence assay of cytochrome P450 3A4 / Qian Cheng and F. Peter Guengerich -- Targeted protein capture for analysis of electrophile-protein adducts / Rebecca E. Connor .....
    [et al.] -- DNA shuffling of cytochrome P450 enzymes / James B.Y.H. Behrendorff, Wayne A. Johnston, and Elizabeth M.J. Gillam -- Measurement of P450 difference spectra using intact cells / Wayne A. Johnston and Elizabeth M.J. Gillam -- DNA shuffling of cytochromes P450 for indigoid pigment production / Nedeljka N. Rosic -- P450 oxidoreductase : genotyping, expression, purification of recombinant protein, and activity assessments of wild-type and mutant protein / Vishal Agrawal and Walter L. Miller -- LICRED : a versatile drop-in vector for rapid generation of redox-self-sufficient cytochromes P450 / Federico Sabbadin, Gideon Grogan, and Neil C. Bruce -- Update on allele nomenclature for human cytochromes P450 and the human cytochrome P450 allele (CYP-allele) nomenclature database / Sarah C. Sim and Magnus Ingelman-Sundberg -- Simultaneous in vivo phenotyping of CYP enzymes / Sussan Ghassabian and Michael Murray -- Detection of regulatory polymorphisms : high-throughput capillary DNase I footprinting / Matthew Hancock and Elizabeth A. Shephard -- Isolation of mouse hepatocytes / Mina Edwards ... [et al.] -- Highly efficient SiRNA and gene transfer into hepatocyte-like HepaRG cells and primary human hepatocytes : new means for drug metabolism and toxicity studies / Véronique Laurent ... [et al.]
  • Títulos relacionados: Série:Methods in molecular biology (Clifton, N.J.) v. 987; Springer protocols (Series)
  • Editor: Totowa, N.J Humana London Springer distributor
  • Data de criação/publicação: 2013
  • Formato: xii, 319 p ill. (some col.) 27 cm.
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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