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Injectability Evaluation of Bone-Graft Substitutes Based on Carrageenan and Hydroxyapatite Nanorods

González, J. I. ; Ossa, C. P. O. Colorado, Henry A ; Wells, Mary ; Dalgaard, Elvi ; Elias, Carlos Nelson ; Figueiredo, Roberto B ; Yang, Wen ; Benavides, Hector Alfredo Calderon ; Mangalaraja, R.V. ; Schoenung, Julie M ; Meyers, Marc André ; Marroquin, Mery Cecilia Gomez ; Brühl, Sonia P ; Garcia-Rincon, Omar ; Costa e Silva, Andre ; Kawasaki, Megumi ; Langdon, Terence G. ; da Cunha Rocha, Adriana

Proceedings of the 3rd Pan American Materials Congress, p.33-46

Cham: Springer International Publishing

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Título:
Injectability Evaluation of Bone-Graft Substitutes Based on Carrageenan and Hydroxyapatite Nanorods
Autor: González, J. I. ; Ossa, C. P. O.
Colorado, Henry A ; Wells, Mary ; Dalgaard, Elvi ; Elias, Carlos Nelson ; Figueiredo, Roberto B ; Yang, Wen ; Benavides, Hector Alfredo Calderon ; Mangalaraja, R.V. ; Schoenung, Julie M ; Meyers, Marc André ; Marroquin, Mery Cecilia Gomez ; Brühl, Sonia P ; Garcia-Rincon, Omar ; Costa e Silva, Andre ; Kawasaki, Megumi ; Langdon, Terence G. ; da Cunha Rocha, Adriana
Materias: Carrageenan ; Hydroxyapatite ; Injectability ; Injectable bone substitute ; Nanorods
Es parte de: Proceedings of the 3rd Pan American Materials Congress, p.33-46
Descripción: The first injectable bone substitutes were introduced for orthopedic trauma applications since more than a decade, and over recent years the number of commercial products has dramatically increased. These substitutes can be injected into a fracture space for augmentation as an alternative to bone graft, or around a screw for augmentation if the bone is weak, so the injectability of the substitute must be optimum with a good behavior within and our of syringe. The aim of this work was to study the injectability of substitutes based on carrageenan CG with 1, 1.5, 2.5 and 60 wt% hydroxyapatite HA nanorods. Initially carrageenan and hydroxyapatite were characterized and then injectability tests were performed with the syringe between the compression plates of a testing machine. The material also was characterized by scanning electron microscopy. The results revealed that none of the samples had phases separation and they did not exceed 300 N of force (97.08, 107.84 and 149 N to each material), that the injectability was 95.71, 93.69 and 90.63% and the CG was a good vehicle for HA nanorods. Therefore, the substitutes are adequate for manual handling.
Títulos relacionados: The Minerals, Metals & Materials Series
Editor: Cham: Springer International Publishing
Idioma: Inglés

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Injectability Evaluation of Bone-Graft Substitutes Based on Carrageenan and Hydroxyapatite Nanorods

Cham: Springer International Publishing

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