Idioma:

Two novel Co(II) complexes with two different Schiff bases: inhibiting growth of human skin cancer cells

Xiao, Y-J ; Diao, Q-C ; Liang, Y-H ; Zeng, K

Brazilian journal of medical and biological research, 2017-01, Vol.50 (7), p.e6390-e6390 [Periódico revisado por pares]

Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)

Texto completo disponível

Citações Citado por

Enviar para

Título:
Two novel Co(II) complexes with two different Schiff bases: inhibiting growth of human skin cancer cells
Autor: Xiao, Y-J ; Diao, Q-C ; Liang, Y-H ; Zeng, K
Assuntos: Analysis ; Antitumor activity ; BIOLOGY ; Biomedical Sciences ; Cell Line, Tumor ; Cell lines ; Chemical properties ; Cobalt - chemistry ; Cobalt - pharmacology ; Cobalt compounds ; Coordination compound ; Crystallography, X-Ray ; Humans ; MEDICINE, RESEARCH & EXPERIMENTAL ; Molecular Structure ; Schiff bases ; Schiff Bases - chemistry ; Schiff Bases - pharmacology ; Skin cancer ; Skin Neoplasms - drug therapy
É parte de: Brazilian journal of medical and biological research, 2017-01, Vol.50 (7), p.e6390-e6390
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Using two flexible Schiff bases, H2L1 and H2L2, two new cobalt II (Co(II))-coordination compounds, namely, Py3CoL1 (1) and Py3CoL2 (2) (Py=pyridine, L1=3,5-ClC6H2(O)C=NC6H3(O)-4-NO2, L2=3,5-BrC6H2(O)C=NC6H3(O)-4-NO2) have been synthesized under solvothermal conditions. Single crystal X-ray structural analysis revealed that compounds 1 and 2 are both six-coordinate in a distorted octahedral geometry, and the 1D chain structure was formed by the π…π and C-H…O interactions or C-H…Cl interaction. The in vitro antitumor activities of 1, 2 and their corresponding organic ligands Py, L1, and L2 were studied and evaluated, in which three human skin cancer cell lines (A-431, HT-144 and SK-MEL-30) were used in the screening tests.
Editor: Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)
Idioma: Inglês;Português

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Anterior Resultado 6 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Two novel Co(II) complexes with two different Schiff bases: inhibiting growth of human skin cancer cells

Xiao, Y-J ; Diao, Q-C ; Liang, Y-H ; Zeng, K

Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)

Buscando em bases de dados remotas. Favor aguardar.