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Agelastatin E, Agelastatin F, and Benzosceptrin C from the Marine Sponge Agelas dendromorpha

Tilvi, Supriya ; Moriou, Céline ; Martin, Marie-Thérèse ; Gallard, Jean-François ; Sorres, Jonathan ; Patel, Kirti ; Petek, Sylvain ; Debitus, Cécile ; Ermolenko, Ludmila ; Al-Mourabit, Ali

Journal of natural products (Washington, D.C.), 2010-04, Vol.73 (4), p.720-723 [Peer Reviewed Journal]

Northbrook, IL: American Chemical Society and American Society of Pharmacognosy

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Title:
Agelastatin E, Agelastatin F, and Benzosceptrin C from the Marine Sponge Agelas dendromorpha
Author: Tilvi, Supriya ; Moriou, Céline ; Martin, Marie-Thérèse ; Gallard, Jean-François ; Sorres, Jonathan ; Patel, Kirti ; Petek, Sylvain ; Debitus, Cécile ; Ermolenko, Ludmila ; Al-Mourabit, Ali
Subjects: Agelas - chemistry ; Agelas dendromorpha ; Alkaloids - chemistry ; Alkaloids - isolation & purification ; Alkaloids - pharmacology ; Animals ; Biological and medical sciences ; Cellular Biology ; Drug Screening Assays, Antitumor ; General pharmacology ; Humans ; Imidazoles ; KB Cells ; Life Sciences ; Marine ; Marine Biology ; Medical sciences ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Oxazolidinones - chemistry ; Oxazolidinones - isolation & purification ; Oxazolidinones - pharmacology ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Pyrroles
Is Part Of: Journal of natural products (Washington, D.C.), 2010-04, Vol.73 (4), p.720-723
Notes: http://dx.doi.org/10.1021/np900539j
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Description: The study of the n-butanol extract of the New Caledonian sponge Agelas dendromorpha led to the isolation and identification of three new pyrrole-2-aminoimidazole (P-2-AI) alkaloids, named agelastatins E (3) and F (4) and benzosceptrin C (5), together with 10 known metabolites, agelastatin A (1), agelastatin D (2), sceptrin (6), manzacidin A, tauroacidin A, taurodispacamide A, nortopsentin D, thymine, longamide, and 4,5-dibromopyrrole-2-carboxamide. Their structures were assigned by spectroscopic data interpretation. All the compounds were tested for cytotoxic activity.
Publisher: Northbrook, IL: American Chemical Society and American Society of Pharmacognosy
Language: English

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Agelastatin E, Agelastatin F, and Benzosceptrin C from the Marine Sponge Agelas dendromorpha

Tilvi, Supriya ; Moriou, Céline ; Martin, Marie-Thérèse ; Gallard, Jean-François ; Sorres, Jonathan ; Patel, Kirti ; Petek, Sylvain ; Debitus, Cécile ; Ermolenko, Ludmila ; Al-Mourabit, Ali

Northbrook, IL: American Chemical Society and American Society of Pharmacognosy

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