skip to main content

Idioma:

The behavioral profile of children aged 1–5 years with sex chromosome trisomy (47,XXX, 47,XXY, 47,XYY)

Urbanus, Evelien ; Swaab, Hanna ; Tartaglia, Nicole ; Cordeiro, Lisa ; Rijn, Sophie

American journal of medical genetics. Part C, Seminars in medical genetics, 2020-06, Vol.184 (2), p.444-455

Hoboken, USA: John Wiley & Sons, Inc

Texto completo disponible

Citas Citado por

Acciones

Título:
The behavioral profile of children aged 1–5 years with sex chromosome trisomy (47,XXX, 47,XXY, 47,XYY)
Autor: Urbanus, Evelien ; Swaab, Hanna ; Tartaglia, Nicole ; Cordeiro, Lisa ; Rijn, Sophie
Materias: Anxiety - diagnosis ; Anxiety - genetics ; Anxiety - physiopathology ; Attention Deficit Disorder with Hyperactivity - diagnosis ; Attention Deficit Disorder with Hyperactivity - genetics ; Attention Deficit Disorder with Hyperactivity - physiopathology ; behavioral development ; behavioral problems ; Child ; Child, Preschool ; Chromosomes, Human, X - genetics ; developmental impact ; Female ; Humans ; Infant ; Male ; Problem Behavior ; psychopathology ; Sex Chromosome Aberrations ; Sex Chromosome Disorders - diagnosis ; Sex Chromosome Disorders - genetics ; Sex Chromosome Disorders - physiopathology ; Sex Chromosome Disorders of Sex Development - diagnosis ; Sex Chromosome Disorders of Sex Development - genetics ; Sex Chromosome Disorders of Sex Development - physiopathology ; sex chromosome trisomy ; Sex Chromosomes - genetics ; Trisomy - diagnosis ; Trisomy - genetics ; Trisomy - physiopathology ; XYY Karyotype - diagnosis ; XYY Karyotype - genetics ; XYY Karyotype - physiopathology
Es parte de: American journal of medical genetics. Part C, Seminars in medical genetics, 2020-06, Vol.184 (2), p.444-455
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descripción: Children with SCT have an increased risk of suboptimal neurodevelopment. Previous studies have shown an elevated risk for neurobehavioral problems in individuals with SCT. However, not much is known about neurobehavioral problems in very young children; knowledge that could help with early identification of children at risk for suboptimal development, and that could help establish targets for early intervention. This study addressed the question of what the behavioral profile of children with SCT aged 1–5 years looks like. In total, 182 children aged 1–5 years participated in this study (NSCT=87, Nnonclinical controls = 95). Recruitment and assessment took place in the Netherlands and the United States. The SCT group was recruited through prospective follow‐up (50%), information seeking parents (31%), and clinical referral (18%). Behavioral profiles were assessed with the child behavior checklist and the ages‐and‐stages social–emotional questionnaire. Levels of parent‐rated problem behavior were higher in children with SCT. Difficulties with overall social–emotional functioning were already present in 1‐year‐olds, and elevated scores were persistent across the full age range. Affective and pervasive developmental behaviors were seen in late toddlerhood and prominent at preschool age. Anxiety, attention deficit, and oppositional defiant behaviors were seen in preschool‐aged children. Within this cross‐sectional study, the developmental trajectory of affective, pervasive developmental, and oppositional defiant behaviors seemed to be different for SCT children than nonclinical controls. Collectively, these results demonstrate the importance of behavioral screening for behavioral problems in routine clinical care for children with SCT from a young age. Social–emotional problems may require special attention, as these problems seem most prominent, showing increased risk across the full age range, and with these problems occurring regardless of the timing of diagnosis, and across all three SCT karyotypes.
Editor: Hoboken, USA: John Wiley & Sons, Inc
Idioma: Inglés

Enlaces

View this record in MEDLINE/PubMed

Volver a la lista de resultados

Ir a la página anterior

Anterior Resultado 5 Siguiente Ir a la siguiente página

Ir a la siguiente página

Realización: Logos de Redes Sociales:

Buscando en bases de datos remotas, por favor espere

Buscando por
enscope:(USP_VIDEOS),scope:("PRIMO"),scope:(USP_FISICO),scope:(USP_EREVISTAS),scope:(USP),scope:(USP_EBOOKS),scope:(USP_PRODUCAO),primo_central_multiple_fe
Mostrar lo que tiene hasta ahora