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1
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

Herman, Sarah E.M. ; Gordon, Amber L. ; Hertlein, Erin ; Ramanunni, Asha ; Zhang, Xiaoli ; Jaglowski, Samantha ; Flynn, Joseph ; Jones, Jeffrey ; Blum, Kristie A. ; Buggy, Joseph J. ; Hamdy, Ahmed ; Johnson, Amy J. ; Byrd, John C.

Blood, 2011-06, Vol.117 (23), p.6287-6296 [Peer Reviewed Journal]

Washington, DC: Elsevier Inc

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2
APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation
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APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation

Cescon, David W ; Haibe-Kains, Benjamin ; Mak, Tak W

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (9), p.2841-2846 [Peer Reviewed Journal]

United States: National Academy of Sciences

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3
Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
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Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma

Shenoy, Niraj ; Bhagat, Tushar D ; Cheville, John ; Lohse, Christine ; Bhattacharyya, Sanchari ; Tischer, Alexander ; Machha, Venkata ; Gordon-Mitchell, Shanisha ; Choudhary, Gaurav ; Wong, Li-Fan ; Gross, LouAnn ; Ressigue, Emily ; Leibovich, Bradley ; Boorjian, Stephen A ; Steidl, Ulrich ; Wu, Xiaosheng ; Pradhan, Kith ; Gartrell, Benjamin ; Agarwal, Beamon ; Pagliaro, Lance ; Suzuki, Masako ; Greally, John M ; Rakheja, Dinesh ; Thompson, R Houston ; Susztak, Katalin ; Witzig, Thomas ; Zou, Yiyu ; Verma, Amit

The Journal of clinical investigation, 2019-04, Vol.129 (4), p.1612-1625 [Peer Reviewed Journal]

United States: American Society for Clinical Investigation

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4
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Gay, Carl M. ; Stewart, C. Allison ; Park, Elizabeth M. ; Diao, Lixia ; Groves, Sarah M. ; Heeke, Simon ; Nabet, Barzin Y. ; Fujimoto, Junya ; Solis, Luisa M. ; Lu, Wei ; Xi, Yuanxin ; Cardnell, Robert J. ; Wang, Qi ; Fabbri, Giulia ; Cargill, Kasey R. ; Vokes, Natalie I. ; Ramkumar, Kavya ; Zhang, Bingnan ; Della Corte, Carminia M. ; Robson, Paul ; Swisher, Stephen G. ; Roth, Jack A. ; Glisson, Bonnie S. ; Shames, David S. ; Wistuba, Ignacio I. ; Wang, Jing ; Quaranta, Vito ; Minna, John ; Heymach, John V. ; Byers, Lauren Averett

Cancer cell, 2021-03, Vol.39 (3), p.346-360.e7 [Peer Reviewed Journal]

United States: Elsevier Inc

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5
The emerging roles of forkhead box (Fox) proteins in cancer
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The emerging roles of forkhead box (Fox) proteins in cancer

Lam, Eric W. -F ; Myatt, Stephen S

Nature reviews. Cancer, 2007-11, Vol.7 (11), p.847-859 [Peer Reviewed Journal]

England: Nature Publishing Group

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6
Circular RNAs function as ceRNAs to regulate and control human cancer progression
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Circular RNAs function as ceRNAs to regulate and control human cancer progression

Zhong, Yaxian ; Du, Yajun ; Yang, Xue ; Mo, Yongzhen ; Fan, Chunmei ; Xiong, Fang ; Ren, Daixi ; Ye, Xin ; Li, Chunwei ; Wang, Yumin ; Wei, Fang ; Guo, Can ; Wu, Xu ; Li, Xiaoling ; Li, Yong ; Li, Guiyuan ; Zeng, Zhaoyang ; Xiong, Wei

Molecular cancer, 2018-04, Vol.17 (1), p.79-11, Article 79 [Peer Reviewed Journal]

England: BioMed Central Ltd

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7
Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network
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Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network

Fish, Jason E ; Cantu Gutierrez, Manuel ; Dang, Lan T ; Khyzha, Nadiya ; Chen, Zhiqi ; Veitch, Shawn ; Cheng, Henry S ; Khor, Melvin ; Antounians, Lina ; Njock, Makon-Sébastien ; Boudreau, Emilie ; Herman, Alexander M ; Rhyner, Alexander M ; Ruiz, Oscar E ; Eisenhoffer, George T ; Medina-Rivera, Alejandra ; Wilson, Michael D ; Wythe, Joshua D

Development (Cambridge), 2017-07, Vol.144 (13), p.2428-2444 [Peer Reviewed Journal]

England: The Company of Biologists Ltd

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8
Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy
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Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy

Strong, Michael J ; Xu, Guorong ; Coco, Joseph ; Baribault, Carl ; Vinay, Dass S ; Lacey, Michelle R ; Strong, Amy L ; Lehman, Teresa A ; Seddon, Michael B ; Lin, Zhen ; Concha, Monica ; Baddoo, Melody ; Ferris, Marybeth ; Swan, Kenneth F ; Sullivan, Deborah E ; Burow, Matthew E ; Taylor, Christopher M ; Flemington, Erik K Lieberman, Paul M.

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003341-e1003341 [Peer Reviewed Journal]

United States: Public Library of Science

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9
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
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Childhood cerebellar tumours mirror conserved fetal transcriptional programs

Vladoiu, Maria C ; El-Hamamy, Ibrahim ; Donovan, Laura K ; Farooq, Hamza ; Holgado, Borja L ; Sundaravadanam, Yogi ; Ramaswamy, Vijay ; Hendrikse, Liam D ; Kumar, Sachin ; Mack, Stephen C ; Lee, John J Y ; Fong, Vernon ; Juraschka, Kyle ; Przelicki, David ; Michealraj, Antony ; Skowron, Patryk ; Luu, Betty ; Suzuki, Hiromichi ; Morrissy, A Sorana ; Cavalli, Florence M G ; Garzia, Livia ; Daniels, Craig ; Wu, Xiaochong ; Qazi, Maleeha A ; Singh, Sheila K ; Chan, Jennifer A ; Marra, Marco A ; Malkin, David ; Dirks, Peter ; Heisler, Lawrence ; Pugh, Trevor ; Ng, Karen ; Notta, Faiyaz ; Thompson, Eric M ; Kleinman, Claudia L ; Joyner, Alexandra L ; Jabado, Nada ; Stein, Lincoln ; Taylor, Michael D

Nature (London), 2019-08, Vol.572 (7767), p.67-73 [Peer Reviewed Journal]

England: Nature Publishing Group

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10
Mitochondrial DNA stress primes the antiviral innate immune response
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Mitochondrial DNA stress primes the antiviral innate immune response

West, A Phillip ; Khoury-Hanold, William ; Staron, Matthew ; Tal, Michal C ; Pineda, Cristiana M ; Lang, Sabine M ; Bestwick, Megan ; Duguay, Brett A ; Raimundo, Nuno ; MacDuff, Donna A ; Kaech, Susan M ; Smiley, James R ; Means, Robert E ; Iwasaki, Akiko ; Shadel, Gerald S

Nature (London), 2015-04, Vol.520 (7548), p.553-557 [Peer Reviewed Journal]

England: Nature Publishing Group

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