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Refined by: collection: PubMed (Medline) remove HighWire Press (Free Journals) remove subject: Samhd1 remove
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1
A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation
A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation
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A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation

St Gelais, Corine ; Kim, Sun Hee ; Maksimova, Victoria V ; Buzovetsky, Olga ; Knecht, Kirsten M ; Shepard, Caitlin ; Kim, Baek ; Xiong, Yong ; Wu, Li Sundquist, Wesley I.

Journal of virology, 2018-03, Vol.92 (6) [Peer Reviewed Journal]

United States: American Society for Microbiology

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2
DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV‐1 infection of macrophages
DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV‐1 infection of macrophages
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DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV‐1 infection of macrophages

Mlcochova, Petra ; Caswell, Sarah J ; Taylor, Ian A ; Towers, Greg J ; Gupta, Ravindra K

The EMBO journal, 2018-01, Vol.37 (1), p.50-62 [Peer Reviewed Journal]

England: Blackwell Publishing Ltd

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3
Elimination of rNMPs from mitochondrial DNA has no effect on its stability
Elimination of rNMPs from mitochondrial DNA has no effect on its stability
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Elimination of rNMPs from mitochondrial DNA has no effect on its stability

Wanrooij, Paulina H. ; Tran, Phong ; Thompson, Liam J. ; Carvalho, Gustavo ; Sharma, Sushma ; Kreisel, Katrin ; Navarrete, Clara ; Feldberg, Anna-Lena ; Watt, Danielle L. ; Nilsson, Anna Karin ; Engqvist, Martin K. M. ; Clausen, Anders R. ; Chabes, Andrei

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (25), p.14306-14313 [Peer Reviewed Journal]

Washington: National Academy of Sciences

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4
Positive selection in dNTPase SAMHD1 throughout mammalian evolution
Positive selection in dNTPase SAMHD1 throughout mammalian evolution
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Positive selection in dNTPase SAMHD1 throughout mammalian evolution

Monit, Christopher ; Morris, Elizabeth R. ; Ruis, Christopher ; Szafran, Bart ; Thiltgen, Grant ; Tsai, Ming-Han Chloe ; Mitchison, N. Avrion ; Bishop, Kate N. ; Stoye, Jonathan P. ; Taylor, Ian A. ; Fassati, Ariberto ; Goldstein, Richard A.

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (37), p.18647-18654 [Peer Reviewed Journal]

United States: National Academy of Sciences

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5
SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 + T Cells
SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 + T Cells
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SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 + T Cells

Antonucci, Jenna M ; Kim, Sun Hee ; St Gelais, Corine ; Bonifati, Serena ; Li, Tai-Wei ; Buzovetsky, Olga ; Knecht, Kirsten M ; Duchon, Alice A ; Xiong, Yong ; Musier-Forsyth, Karin ; Wu, Li Sundquist, Wesley I.

Journal of virology, 2018-08, Vol.92 (15) [Peer Reviewed Journal]

United States: American Society for Microbiology

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6
SAMHD1‐mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination
SAMHD1‐mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination
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SAMHD1‐mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination

Husain, Afzal ; Xu, Jianliang ; Fujii, Hodaka ; Nakata, Mikiyo ; Kobayashi, Maki ; Wang, Ji‐Yang ; Rehwinkel, Jan ; Honjo, Tasuku ; Begum, Nasim A

The EMBO journal, 2020-08, Vol.39 (15), p.e102931-n/a [Peer Reviewed Journal]

England: Blackwell Publishing Ltd

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7
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways
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SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways

Chen, Shuliang ; Bonifati, Serena ; Qin, Zhihua ; St. Gelais, Corine ; Kodigepalli, Karthik M. ; Barrett, Bradley S. ; Kim, Sun Hee ; Antonucci, Jenna M. ; Ladner, Katherine J. ; Buzovetsky, Olga ; Knecht, Kirsten M. ; Xiong, Yong ; Yount, Jacob S. ; Guttridge, Denis C. ; Santiago, Mario L. ; Wu, Li

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (16), p.E3798-E3807 [Peer Reviewed Journal]

United States: National Academy of Sciences

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8
Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins
Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins
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Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins

Bowen, Nicole E. ; Temple, Joshua ; Shepard, Caitlin ; Oo, Adrian ; Arizaga, Fidel ; Kapoor-Vazirani, Priya ; Persaud, Mirjana ; Yu, Corey H. ; Kim, Dong-Hyun ; Schinazi, Raymond F. ; Ivanov, Dmitri N. ; Diaz-Griffero, Felipe ; Yu, David S. ; Xiong, Yong ; Kim, Baek

The Journal of biological chemistry, 2021-10, Vol.297 (4), p.101170, Article 101170 [Peer Reviewed Journal]

United States: Elsevier Inc

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9
The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
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The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1

Knecht, Kirsten M. ; Buzovetsky, Olga ; Schneider, Constanze ; Thomas, Dominique ; Srikanth, Vishok ; Kaderali, Lars ; Tofoleanu, Florentina ; Reiss, Krystle ; Ferreirós, Nerea ; Geisslinger, Gerd ; Batista, Victor S. ; Ji, Xiaoyun ; Cinatl, Jindrich ; Keppler, Oliver T. ; Xiong, Yong

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (43), p.E10022-E10031 [Peer Reviewed Journal]

United States: National Academy of Sciences

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10
Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages
Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages
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Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages

Bowen, Nicole E. ; Tao, Sijia ; Cho, Young-Jae ; Schinazi, Raymond F. ; Kim, Baek

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.104984-104984, Article 104984 [Peer Reviewed Journal]

United States: Elsevier Inc

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