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1 |
Material Type: Artigo
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Bioactive pyrrole-based compounds with target selectivityLi Petri, Giovanna ; Spanò, Virginia ; Spatola, Roberto ; Holl, Ralph ; Raimondi, Maria Valeria ; Barraja, Paola ; Montalbano, AlessandraEuropean journal of medicinal chemistry, 2020-12, Vol.208, p.112783-112783, Article 112783 [Periódico revisado por pares]France: Elsevier Masson SASTexto completo disponível |
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Material Type: Artigo
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Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitorsGümüş, Mehmet ; Babacan, Şemsi N. ; Demir, Yeliz ; Sert, Yusuf ; Koca, İrfan ; Gülçin, İlhamiArchiv der Pharmazie (Weinheim), 2022-01, Vol.355 (1), p.e2100242-n/a [Periódico revisado por pares]Germany: Wiley Subscription Services, IncTexto completo disponível |
3 |
Material Type: Artigo
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Pyrrole: An insight into recent pharmacological advances with structure activity relationshipAhmad, Shujauddin ; Alam, Ozair ; Naim, Mohd. Javed ; Shaquiquzzaman, Mohammad ; Alam, M. Mumtaz ; Iqbal, MuzaffarEuropean journal of medicinal chemistry, 2018-09, Vol.157, p.527-561 [Periódico revisado por pares]France: Elsevier Masson SASTexto completo disponível |
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Material Type: Artigo
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Identification of N‑{cis-3-[Methyl(7H‑pyrrolo[2,3‑d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune DiseasesVazquez, Michael L ; Kaila, Neelu ; Strohbach, Joseph W ; Trzupek, John D ; Brown, Matthew F ; Flanagan, Mark E ; Mitton-Fry, Mark J ; Johnson, Timothy A ; TenBrink, Ruth E ; Arnold, Eric P ; Basak, Arindrajit ; Heasley, Steven E ; Kwon, Soojin ; Langille, Jonathan ; Parikh, Mihir D ; Griffin, Sarah H ; Casavant, Jeffrey M ; Duclos, Brian A ; Fenwick, Ashley E ; Harris, Thomas M ; Han, Seungil ; Caspers, Nicole ; Dowty, Martin E ; Yang, Xin ; Banker, Mary Ellen ; Hegen, Martin ; Symanowicz, Peter T ; Li, Li ; Wang, Lu ; Lin, Tsung H ; Jussif, Jason ; Clark, James D ; Telliez, Jean-Baptiste ; Robinson, Ralph P ; Unwalla, RayJournal of medicinal chemistry, 2018-02, Vol.61 (3), p.1130-1152 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Structural insights into µ-opioid receptor activationHuang, Weijiao ; Manglik, Aashish ; Venkatakrishnan, A J ; Laeremans, Toon ; Feinberg, Evan N ; Sanborn, Adrian L ; Kato, Hideaki E ; Livingston, Kathryn E ; Thorsen, Thor S ; Kling, Ralf C ; Granier, Sébastien ; Gmeiner, Peter ; Husbands, Stephen M ; Traynor, John R ; Weis, William I ; Steyaert, Jan ; Dror, Ron O ; Kobilka, Brian KNature (London), 2015-08, Vol.524 (7565), p.315-321 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancerFaivre, Emily J ; McDaniel, Keith F ; Albert, Daniel H ; Mantena, Srinivasa R ; Plotnik, Joshua P ; Wilcox, Denise ; Zhang, Lu ; Bui, Mai H ; Sheppard, George S ; Wang, Le ; Sehgal, Vasudha ; Lin, Xiaoyu ; Huang, Xiaoli ; Lu, Xin ; Uziel, Tamar ; Hessler, Paul ; Lam, Lloyd T ; Bellin, Richard J ; Mehta, Gaurav ; Fidanze, Steve ; Pratt, John K ; Liu, Dachun ; Hasvold, Lisa A ; Sun, Chaohong ; Panchal, Sanjay C ; Nicolette, John J ; Fossey, Stacey L ; Park, Chang H ; Longenecker, Kenton ; Bigelow, Lance ; Torrent, Maricel ; Rosenberg, Saul H ; Kati, Warren M ; Shen, YuNature (London), 2020-02, Vol.578 (7794), p.306-310 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
7 |
Material Type: Artigo
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Tofacitinib: A Review in Rheumatoid ArthritisDhillon, SohitaDrugs (New York, N.Y.), 2017-12, Vol.77 (18), p.1987-2001 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
8 |
Material Type: Artigo
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Diketopyrrolopyrrole–Triphenylamine Organic Nanoparticles as Multifunctional Reagents for Photoacoustic Imaging-Guided Photodynamic/Photothermal Synergistic Tumor TherapyCai, Yu ; Liang, Pingping ; Tang, Qianyun ; Yang, Xiaoyan ; Si, Weili ; Huang, Wei ; Zhang, Qi ; Dong, XiaochenACS nano, 2017-01, Vol.11 (1), p.1054-1063 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
9 |
Material Type: Artigo
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From Anthramycin to Pyrrolobenzodiazepine (PBD)‐Containing Antibody–Drug Conjugates (ADCs)Mantaj, Julia ; Jackson, Paul J. M. ; Rahman, Khondaker M. ; Thurston, David E.Angewandte Chemie (International ed.), 2017-01, Vol.56 (2), p.462-488 [Periódico revisado por pares]Germany: Wiley Subscription Services, IncTexto completo disponível |
10 |
Material Type: Artigo
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Pyrroloquinoline Quinone Prevents Oxidative Stress-Induced Neuronal Death Probably through Changes in Oxidative Status of DJ-1Nunome, Kana ; Miyazaki, Shin ; Nakano, Masahiko ; Iguchi-Ariga, Sanae ; Ariga, HiroyoshiBiological and Pharmaceutical Bulletin, 2008/07/01, Vol.31(7), pp.1321-1326 [Periódico revisado por pares]Japan: The Pharmaceutical Society of JapanTexto completo disponível |