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Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins
Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins
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Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

Sinha, Sharmistha ; Lopes, Dahabada H. J ; Du, Zhenming ; Pang, Eric S ; Shanmugam, Akila ; Lomakin, Aleksey ; Talbiersky, Peter ; Tennstaedt, Annette ; McDaniel, Kirsten ; Bakshi, Reena ; Kuo, Pei-Yi ; Ehrmann, Michael ; Benedek, George B ; Loo, Joseph A ; Klärner, Frank-Gerrit ; Schrader, Thomas ; Wang, Chunyu ; Bitan, Gal

Journal of the American Chemical Society, 2011-10, Vol.133 (42), p.16958-16969 [Periódico revisado por pares]

United States: American Chemical Society

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2
Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism
Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism
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Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism

Lopes, Dahabada H. J ; Attar, Aida ; Nair, Gayatri ; Hayden, Eric Y ; Du, Zhenming ; McDaniel, Kirsten ; Dutt, Som ; Bandmann, Heinz ; Bravo-Rodriguez, Kenny ; Mittal, Sumit ; Klärner, Frank-Gerrit ; Wang, Chunyu ; Sanchez-Garcia, Elsa ; Schrader, Thomas ; Bitan, Gal

ACS chemical biology, 2015-06, Vol.10 (6), p.1555-1569 [Periódico revisado por pares]

United States: American Chemical Society

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3
Induction of Methionine-Sulfoxide Reductases Protects Neurons from Amyloid β-Protein Insults in Vitro and in Vivo
Induction of Methionine-Sulfoxide Reductases Protects Neurons from Amyloid β-Protein Insults in Vitro and in Vivo
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Induction of Methionine-Sulfoxide Reductases Protects Neurons from Amyloid β-Protein Insults in Vitro and in Vivo

Moskovitz, Jackob ; Maiti, Panchanan ; Lopes, Dahabada H. J ; Oien, Derek B ; Attar, Aida ; Liu, Tingyu ; Mittal, Shivina ; Hayes, Jane ; Bitan, Gal

Biochemistry (Easton), 2011-12, Vol.50 (49), p.10687-10697 [Periódico revisado por pares]

United States: American Chemical Society

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4
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
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Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease

Koronyo-Hamaoui, Maya ; Sheyn, Julia ; Hayden, Eric Y ; Li, Songlin ; Fuchs, Dieu-Trang ; Regis, Giovanna C ; Lopes, Dahabada H J ; Black, Keith L ; Bernstein, Kenneth E ; Teplow, David B ; Fuchs, Sebastien ; Koronyo, Yosef ; Rentsendorj, Altan

Brain (London, England : 1878), 2020-01, Vol.143 (1), p.336-358 [Periódico revisado por pares]

England: Oxford University Press

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5
A Key Role for Lysine Residues in Amyloid β-Protein Folding, Assembly, and Toxicity
A Key Role for Lysine Residues in Amyloid β-Protein Folding, Assembly, and Toxicity
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A Key Role for Lysine Residues in Amyloid β-Protein Folding, Assembly, and Toxicity

Sinha, Sharmistha ; Lopes, Dahabada H. J ; Bitan, Gal

ACS chemical neuroscience, 2012-06, Vol.3 (6), p.473-481 [Periódico revisado por pares]

United States: American Chemical Society

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6
C-Terminal Tetrapeptides Inhibit Aβ42-Induced Neurotoxicity Primarily through Specific Interaction at the N-Terminus of Aβ42
C-Terminal Tetrapeptides Inhibit Aβ42-Induced Neurotoxicity Primarily through Specific Interaction at the N-Terminus of Aβ42
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C-Terminal Tetrapeptides Inhibit Aβ42-Induced Neurotoxicity Primarily through Specific Interaction at the N-Terminus of Aβ42

Li, Huiyuan ; Du, Zhenming ; Lopes, Dahabada H. J ; Fradinger, Erica A ; Wang, Chunyu ; Bitan, Gal

Journal of medicinal chemistry, 2011-12, Vol.54 (24), p.8451-8460 [Periódico revisado por pares]

United States: American Chemical Society

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7
Tranilast Binds to Aβ Monomers and Promotes Aβ Fibrillation
Tranilast Binds to Aβ Monomers and Promotes Aβ Fibrillation
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Tranilast Binds to Aβ Monomers and Promotes Aβ Fibrillation

Connors, Christopher R ; Rosenman, David J ; Lopes, Dahabada H. J ; Mittal, Shivina ; Bitan, Gal ; Sorci, Mirco ; Belfort, Georges ; Garcia, Angel ; Wang, Chunyu

Biochemistry (Easton), 2013-06, Vol.52 (23), p.3995-4002 [Periódico revisado por pares]

United States: American Chemical Society

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8
Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline
Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline
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Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline

Bernstein, Kenneth E ; Koronyo, Yosef ; Salumbides, Brenda C ; Sheyn, Julia ; Pelissier, Lindsey ; Lopes, Dahabada H J ; Shah, Kandarp H ; Bernstein, Ellen A ; Fuchs, Dieu-Trang ; Yu, Jeff J-Y ; Pham, Michael ; Black, Keith L ; Shen, Xiao Z ; Fuchs, Sebastien ; Koronyo-Hamaoui, Maya

The Journal of clinical investigation, 2014-03, Vol.124 (3), p.1000-1012 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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9
A Two-Step Strategy for Structure-Activity Relationship Studies of N-Methylated Aβ42 C-Terminal Fragments as Aβ42 Toxicity Inhibitors
A Two-Step Strategy for Structure-Activity Relationship Studies of N-Methylated Aβ42 C-Terminal Fragments as Aβ42 Toxicity Inhibitors
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A Two-Step Strategy for Structure-Activity Relationship Studies of N-Methylated Aβ42 C-Terminal Fragments as Aβ42 Toxicity Inhibitors

Li, Huiyuan ; Zemel, Reeve ; Lopes, Dahabada H. J. ; Monien, Bernhard H. ; Bitan, Gal

ChemMedChem, 2012-03, Vol.7 (3), p.515-522 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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10
Amyloidogenicity and Cytotoxicity of Recombinant Mature Human Islet Amyloid Polypeptide (rhIAPP)
Amyloidogenicity and Cytotoxicity of Recombinant Mature Human Islet Amyloid Polypeptide (rhIAPP)
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Amyloidogenicity and Cytotoxicity of Recombinant Mature Human Islet Amyloid Polypeptide (rhIAPP)

Dahabada H. J. Lopes ; Christian Colin ; Theri L. Degaki ; Ana Christina V. de Sousa ; Marcelo N. N. Vieira ; Adriano Sebollela ; Ana M. Blanco Martinez ; Carlos Bloch, Jr ; Sérgio T. Ferreira ; Mari C. Sogayar

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42803-42810 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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