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VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection
VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection
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VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection

Da Costa, Laurène ; Roche, Manon ; Scheers, Els ; Coluccia, Antonio ; Neyts, Johan ; Terme, Thierry ; Leyssen, Pieter ; Silvestri, Romano ; Vanelle, Patrice

European journal of medicinal chemistry, 2016-06, Vol.115, p.453-462 [Periódico revisado por pares]

France: Elsevier Masson SAS

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2
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
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Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis

Pacchiano, Fabio ; Carta, Fabrizio ; McDonald, Paul C ; Lou, Yuanmei ; Vullo, Daniela ; Scozzafava, Andrea ; Dedhar, Shoukat ; Supuran, Claudiu T

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1896-1902 [Periódico revisado por pares]

United States: American Chemical Society

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3
Disruption of endocytosis through chemical inhibition of clathrin heavy chain function
Disruption of endocytosis through chemical inhibition of clathrin heavy chain function
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Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Dejonghe, Wim ; Sharma, Isha ; Denoo, Bram ; De Munck, Steven ; Lu, Qing ; Mishev, Kiril ; Bulut, Haydar ; Mylle, Evelien ; De Rycke, Riet ; Vasileva, Mina ; Savatin, Daniel V ; Nerinckx, Wim ; Staes, An ; Drozdzecki, Andrzej ; Audenaert, Dominique ; Yperman, Klaas ; Madder, Annemieke ; Friml, Jiří ; Van Damme, Daniël ; Gevaert, Kris ; Haucke, Volker ; Savvides, Savvas N ; Winne, Johan ; Russinova, Eugenia

Nature chemical biology, 2019-06, Vol.15 (6), p.641-649 [Periódico revisado por pares]

United States: Nature Publishing Group

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4
Design, synthesis and biological evaluation of pyrazole-aromatic containing carboxamides as potent SDH inhibitors
Design, synthesis and biological evaluation of pyrazole-aromatic containing carboxamides as potent SDH inhibitors
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Design, synthesis and biological evaluation of pyrazole-aromatic containing carboxamides as potent SDH inhibitors

Yu, Bin ; Zhao, Bin ; Hao, Zesheng ; Chen, Lei ; Cao, Lixin ; Guo, Xiaofeng ; Zhang, Nailou ; Yang, Dongyan ; Tang, Liangfu ; Fan, Zhijin

European journal of medicinal chemistry, 2021-03, Vol.214, p.113230, Article 113230 [Periódico revisado por pares]

France: Elsevier Masson SAS

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5
Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor
Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor
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Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor

Donthamsetti, Prashant ; Konrad, David B ; Hetzler, Belinda ; Fu, Zhu ; Trauner, Dirk ; Isacoff, Ehud Y

Journal of the American Chemical Society, 2021-06, Vol.143 (24), p.8951-8956 [Periódico revisado por pares]

United States: American Chemical Society

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6
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
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Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Fang, Sungsoon ; Suh, Jae Myoung ; Reilly, Shannon M ; Yu, Elizabeth ; Osborn, Olivia ; Lackey, Denise ; Yoshihara, Eiji ; Perino, Alessia ; Jacinto, Sandra ; Lukasheva, Yelizaveta ; Atkins, Annette R ; Khvat, Alexander ; Schnabl, Bernd ; Yu, Ruth T ; Brenner, David A ; Coulter, Sally ; Liddle, Christopher ; Schoonjans, Kristina ; Olefsky, Jerrold M ; Saltiel, Alan R ; Downes, Michael ; Evans, Ronald M

Nature medicine, 2015-02, Vol.21 (2), p.159-165 [Periódico revisado por pares]

United States: Nature Publishing Group

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7
Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example
Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example
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Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example

Rombouts, Frederik J. R ; Tovar, Fulgencio ; Austin, Nigel ; Tresadern, Gary ; Trabanco, Andrés A

Journal of medicinal chemistry, 2015-12, Vol.58 (23), p.9287-9295 [Periódico revisado por pares]

United States: American Chemical Society

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8
Diphenyl diselenide abrogates brain oxidative injury and neurobehavioural deficits associated with pesticide chlorpyrifos exposure in rats
Diphenyl diselenide abrogates brain oxidative injury and neurobehavioural deficits associated with pesticide chlorpyrifos exposure in rats
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Diphenyl diselenide abrogates brain oxidative injury and neurobehavioural deficits associated with pesticide chlorpyrifos exposure in rats

Adedara, Isaac A. ; Owoeye, Olatunde ; Awogbindin, Ifeoluwa O. ; Ajayi, Babajide O. ; Rocha, Joao B.T. ; Farombi, Ebenezer O.

Chemico-biological interactions, 2018-12, Vol.296, p.105-116 [Periódico revisado por pares]

Ireland: Elsevier B.V

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9
A covalent organic framework as a nanocarrier for synergistic phototherapy and immunotherapy
A covalent organic framework as a nanocarrier for synergistic phototherapy and immunotherapy
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A covalent organic framework as a nanocarrier for synergistic phototherapy and immunotherapy

Zhou, Ying ; Liu, Sainan ; Hu, Chunling ; Cai, Lihan ; Pang, Maolin

Journal of materials chemistry. B, Materials for biology and medicine, 2020-07, Vol.8 (25), p.5451-5459 [Periódico revisado por pares]

England: Royal Society of Chemistry

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10
Construction and activity evaluation of novel benzodioxane derivatives as dual-target antifungal inhibitors
Construction and activity evaluation of novel benzodioxane derivatives as dual-target antifungal inhibitors
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Construction and activity evaluation of novel benzodioxane derivatives as dual-target antifungal inhibitors

An, Yunfei ; Liu, Wenxia ; Xie, Honglei ; Fan, Haiyan ; Han, Jun ; Sun, Bin

European journal of medicinal chemistry, 2022-01, Vol.227, p.113950-113950, Article 113950 [Periódico revisado por pares]

France: Elsevier Masson SAS

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