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1
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
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Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

Markmiller, Sebastian ; Soltanieh, Sahar ; Server, Kari L. ; Mak, Raymond ; Jin, Wenhao ; Fang, Mark Y. ; Luo, En-Ching ; Krach, Florian ; Yang, Dejun ; Sen, Anindya ; Fulzele, Amit ; Wozniak, Jacob M. ; Gonzalez, David J. ; Kankel, Mark W. ; Gao, Fen-Biao ; Bennett, Eric J. ; Lécuyer, Eric ; Yeo, Gene W.

Cell, 2018-01, Vol.172 (3), p.590-604.e13 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis
Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis
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Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis

Goutman, Stephen A ; Hardiman, Orla ; Al-Chalabi, Ammar ; Chió, Adriano ; Savelieff, Masha G ; Kiernan, Matthew C ; Feldman, Eva L

Lancet neurology, 2022-05, Vol.21 (5), p.465-479 [Periódico revisado por pares]

England: Elsevier Ltd

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3
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

Yu, Chien-Hsiung ; Davidson, Sophia ; Harapas, Cassandra R. ; Hilton, James B. ; Mlodzianoski, Michael J. ; Laohamonthonkul, Pawat ; Louis, Cynthia ; Low, Ronnie Ren Jie ; Moecking, Jonas ; De Nardo, Dominic ; Balka, Katherine R. ; Calleja, Dale J. ; Moghaddas, Fiona ; Ni, Erya ; McLean, Catriona A. ; Samson, Andre L. ; Tyebji, Shiraz ; Tonkin, Christopher J. ; Bye, Christopher R. ; Turner, Bradley J. ; Pepin, Genevieve ; Gantier, Michael P. ; Rogers, Kelly L. ; McArthur, Kate ; Crouch, Peter J. ; Masters, Seth L.

Cell, 2020-10, Vol.183 (3), p.636-649.e18 [Periódico revisado por pares]

United States: Elsevier Inc

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4
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Brown, Anna-Leigh ; Wilkins, Oscar G ; Keuss, Matthew J ; Hill, Sarah E ; Zanovello, Matteo ; Lee, Weaverly Colleen ; Bampton, Alexander ; Lee, Flora C Y ; Masino, Laura ; Qi, Yue A ; Bryce-Smith, Sam ; Gatt, Ariana ; Hallegger, Martina ; Fagegaltier, Delphine ; Phatnani, Hemali ; Newcombe, Jia ; Gustavsson, Emil K ; Seddighi, Sahba ; Reyes, Joel F ; Coon, Steven L ; Ramos, Daniel ; Schiavo, Giampietro ; Fisher, Elizabeth M C ; Raj, Towfique ; Secrier, Maria ; Lashley, Tammaryn ; Ule, Jernej ; Buratti, Emanuele ; Humphrey, Jack ; Ward, Michael E ; Fratta, Pietro

Nature (London), 2022-03, Vol.603 (7899), p.131-137 [Periódico revisado por pares]

England: Nature Publishing Group

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5
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
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RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

Liao, Ya-Cheng ; Fernandopulle, Michael S. ; Wang, Guozhen ; Choi, Heejun ; Hao, Ling ; Drerup, Catherine M. ; Patel, Rajan ; Qamar, Seema ; Nixon-Abell, Jonathon ; Shen, Yi ; Meadows, William ; Vendruscolo, Michele ; Knowles, Tuomas P.J. ; Nelson, Matthew ; Czekalska, Magdalena A. ; Musteikyte, Greta ; Gachechiladze, Mariam A. ; Stephens, Christina A. ; Pasolli, H. Amalia ; Forrest, Lucy R. ; St George-Hyslop, Peter ; Lippincott-Schwartz, Jennifer ; Ward, Michael E.

Cell, 2019-09, Vol.179 (1), p.147-164.e20 [Periódico revisado por pares]

United States: Elsevier Inc

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6
TDP-43 is intercellularly transmitted across axon terminals
TDP-43 is intercellularly transmitted across axon terminals
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TDP-43 is intercellularly transmitted across axon terminals

Feiler, Marisa S ; Strobel, Benjamin ; Freischmidt, Axel ; Helferich, Anika M ; Kappel, Julia ; Brewer, Bryson M ; Li, Deyu ; Thal, Dietmar R ; Walther, Paul ; Ludolph, Albert C ; Danzer, Karin M ; Weishaupt, Jochen H

The Journal of cell biology, 2015-11, Vol.211 (4), p.897-911 [Periódico revisado por pares]

United States: The Rockefeller University Press

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7
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

van Rheenen, Wouter ; Bakker, Mark K ; van Vugt, Joke J F A ; de Klein, Niek ; Westra, Harm-Jan ; Bakker, Olivier B ; Deelen, Patrick ; Hannon, Eilis ; Dolzhenko, Egor ; Gawor, Klara ; Westeneng, Henk-Jan ; Kooyman, Maarten ; Heverin, Mark ; Shatunov, Aleksey ; Ticozzi, Nicola ; Cooper-Knock, Johnathan ; Gromicho, Marta ; Chandran, Siddharthan ; Pal, Suvankar ; Shaw, Pamela J ; Hardy, John ; Orrell, Richard W ; Meyer, Thomas ; Lauria, Giuseppe ; Cereda, Cristina ; Sproviero, Daisy ; D'Alfonso, Sandra ; Sorarù, Gianni ; Siciliano, Gabriele ; Filosto, Massimiliano ; Padovani, Alessandro ; Calvo, Andrea ; Canosa, Antonio ; Grassano, Maurizio ; Beghi, Ettore ; Logroscino, Giancarlo ; Nefussy, Beatrice ; Lerner, Yossef ; Gotkine, Marc ; Baloh, Robert H ; Bell, Shaughn ; Vourc'h, Patrick ; Couratier, Philippe ; Salachas, François ; Assialioui, Abdelilah ; Dion, Patrick A ; Ross, Jay P ; Brenner, David ; Freischmidt, Axel ; Bensimon, Gilbert ; Brice, Alexis ; Saker-Delye, Safa ; Wood, Nicholas W ; Topp, Simon ; Lieb, Wolfgang ; Franke, Andre ; Ripke, Stephan ; Braun, Alice ; Hofman, Albert ; Cichon, Sven ; Nöthen, Markus M ; Traynor, Bryan J ; Singleton, Andrew B ; Mitne Neto, Miguel ; Ophoff, Roel A ; Wiedau-Pazos, Martina ; Lomen-Hoerth, Catherine ; Grosskreutz, Julian ; Gaur, Nayana ; Ilse, Benjamin ; Stubendorff, Beatrice ; Hübner, Christian A ; Graff, Caroline ; Fominykh, Vera ; Demeshonok, Vera ; Rogelj, Boris ; Zidar, Janez ; Ravnik-Glavač, Metka ; Drory, Vivian ; Povedano, Monica ; Blair, Ian P ; Kiernan, Matthew C ; McCombe, Pamela A ; Pamphlett, Roger ; Steyn, Frederik J ; de Carvalho, Mamede ; Petri, Susanne ; Weber, Markus ; Brown, Jr, Robert H ; Shaw, Christopher E ; Andersen, Peter M ; Groen, Ewout J N ; Garton, Fleur C ; Mill, Jonathan ; Hardiman, Orla ; Tsai, Ellen ; Runz, Heiko ; Al-Chalabi, Ammar ; van den Berg, Leonard H ; Veldink, Jan H

Nature genetics, 2021-12, Vol.53 (12), p.1636-1648 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1
Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1
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Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1

Kiskinis, Evangelos ; Sandoe, Jackson ; Williams, Luis A. ; Boulting, Gabriella L. ; Moccia, Rob ; Wainger, Brian J. ; Han, Steve ; Peng, Theodore ; Thams, Sebastian ; Mikkilineni, Shravani ; Mellin, Cassidy ; Merkle, Florian T. ; Davis-Dusenbery, Brandi N. ; Ziller, Michael ; Oakley, Derek ; Ichida, Justin ; Di Costanzo, Stefania ; Atwater, Nick ; Maeder, Morgan L. ; Goodwin, Mathew J. ; Nemesh, James ; Handsaker, Robert E. ; Paull, Daniel ; Noggle, Scott ; McCarroll, Steven A. ; Joung, J. Keith ; Woolf, Clifford J. ; Brown, Robert H. ; Eggan, Kevin

Cell stem cell, 2014-06, Vol.14 (6), p.781-795 [Periódico revisado por pares]

United States: Elsevier Inc

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9
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
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C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

Lee, Kyung-Ha ; Zhang, Peipei ; Kim, Hong Joo ; Mitrea, Diana M. ; Sarkar, Mohona ; Freibaum, Brian D. ; Cika, Jaclyn ; Coughlin, Maura ; Messing, James ; Molliex, Amandine ; Maxwell, Brian A. ; Kim, Nam Chul ; Temirov, Jamshid ; Moore, Jennifer ; Kolaitis, Regina-Maria ; Shaw, Timothy I. ; Bai, Bing ; Peng, Junmin ; Kriwacki, Richard W. ; Taylor, J. Paul

Cell, 2016-10, Vol.167 (3), p.774-788.e17 [Periódico revisado por pares]

United States: Elsevier Inc

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10
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
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FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

Qamar, Seema ; Wang, GuoZhen ; Randle, Suzanne J. ; Ruggeri, Francesco Simone ; Varela, Juan A. ; Lin, Julie Qiaojin ; Phillips, Emma C. ; Miyashita, Akinori ; Williams, Declan ; Ströhl, Florian ; Meadows, William ; Ferry, Rodylyn ; Dardov, Victoria J. ; Tartaglia, Gian G. ; Farrer, Lindsay A. ; Kaminski Schierle, Gabriele S. ; Kaminski, Clemens F. ; Holt, Christine E. ; Fraser, Paul E. ; Schmitt-Ulms, Gerold ; Klenerman, David ; Knowles, Tuomas ; Vendruscolo, Michele ; St George-Hyslop, Peter

Cell, 2018-04, Vol.173 (3), p.720-734.e15 [Periódico revisado por pares]

United States: Elsevier Inc

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