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The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
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The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity

Wang, Wenzhang ; Wang, Luwen ; Lu, Junjie ; Siedlak, Sandra L ; Fujioka, Hisashi ; Liang, Jingjing ; Jiang, Sirui ; Ma, Xiaopin ; Jiang, Zhen ; da Rocha, Edroaldo Lummertz ; Sheng, Max ; Choi, Heewon ; Lerou, Paul H ; Li, Hu ; Wang, Xinglong

Nature medicine, 2016-08, Vol.22 (8), p.869-878 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
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Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

Wang, Xinglong ; Su, Bo ; Siedlak, Sandra L ; Moreira, Paula I ; Fujioka, Hisashi ; Wang, Yang ; Casadesus, Gemma ; Zhu, Xiongwei

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (49), p.19318-19323 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease
VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease
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VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

Niu, Mengyue ; Zhao, Fanpeng ; Bondelid, Karina ; Siedlak, Sandra L. ; Torres, Sandy ; Fujioka, Hisashi ; Wang, Wenzhang ; Liu, Jun ; Zhu, Xiongwei

Aging cell, 2021-05, Vol.20 (5), p.e13347-n/a [Periódico revisado por pares]

England: John Wiley & Sons, Inc

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4
MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons
MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons
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MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons

Wang, Wenzhang ; Zhang, Fan ; Li, Li ; Tang, Fangqiang ; Siedlak, Sandra L. ; Fujioka, Hisashi ; Liu, Yingchao ; Su, Bo ; Pi, Yan ; Wang, Xinglong

The Journal of biological chemistry, 2015-01, Vol.290 (1), p.168-182 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation
Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation
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Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

Blair, Jeffrey A ; Wang, Chunyu ; Hernandez, Damarys ; Siedlak, Sandra L ; Rodgers, Mark S ; Achar, Rojan K ; Fahmy, Lara M ; Torres, Sandy L ; Petersen, Robert B ; Zhu, Xiongwei ; Casadesus, Gemma ; Lee, Hyoung-Gon Gong, Cheng-Xin

PloS one, 2016-03, Vol.11 (3), p.e0151615-e0151615 [Periódico revisado por pares]

United States: Public Library of Science

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6
Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance
Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance
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Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

Bonda, David J. ; Stone, Jeremy G. ; Torres, Sandy L. ; Siedlak, Sandra L. ; Perry, George ; Kryscio, Richard ; Jicha, Gregory ; Casadesus, Gemma ; Smith, Mark A. ; Zhu, Xiongwei ; Lee, Hyoung‐gon

Journal of neurochemistry, 2014-01, Vol.128 (1), p.162-172 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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7
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment
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Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

Smith, Mark A ; Zhu, Xiongwei ; Tabaton, Massimo ; Liu, Gang ; McKeel, Jr, Daniel W ; Cohen, Mark L ; Wang, Xinglong ; Siedlak, Sandra L ; Dwyer, Barney E ; Hayashi, Takaaki ; Nakamura, Masao ; Nunomura, Akihiko ; Perry, George Lovell, Mark A.

Journal of Alzheimer's disease, 2010-01, Vol.19 (1), p.363-372 [Periódico revisado por pares]

Netherlands

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8
Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex
Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex
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Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

Jiang, Sirui ; Nandy, Priya ; Wang, Wenzhang ; Ma, Xiaopin ; Hsia, Jeffrey ; Wang, Chunyu ; Wang, Zhenlian ; Niu, Mengyue ; Siedlak, Sandra L ; Torres, Sandy ; Fujioka, Hisashi ; Xu, Ying ; Lee, Hyoung-Gon ; Perry, George ; Liu, Jun ; Zhu, Xiongwei

Molecular neurodegeneration, 2018-02, Vol.13 (1), p.5-5, Article 5 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

Wang, Luwen ; Gao, Ju ; Liu, Jingyi ; Siedlak, Sandra L. ; Torres, Sandy ; Fujioka, Hisashi ; Huntley, Mikayla L. ; Jiang, Yinfei ; Ji, Haiyan ; Yan, Tingxiang ; Harland, Micah ; Termsarasab, Pichet ; Zeng, Sophia ; Jiang, Zhen ; Liang, Jingjing ; Perry, George ; Hoppel, Charles ; Zhang, Cheng ; Li, Hu ; Wang, Xinglong

Cell metabolism, 2018-09, Vol.28 (3), p.400-414.e8 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer's disease brain
Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer's disease brain
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Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer's disease brain

Wang, Wenzhang ; Zhao, Fanpeng ; Lu, Yubing ; Siedlak, Sandra L ; Fujioka, Hisashi ; Feng, Hao ; Perry, George ; Zhu, Xiongwei

Acta neuropathologica communications, 2023-03, Vol.11 (1), p.54-54, Article 54 [Periódico revisado por pares]

England: BioMed Central Ltd

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