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Using human genetics to understand the disease impacts of testosterone in men and women
Using human genetics to understand the disease impacts of testosterone in men and women
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Using human genetics to understand the disease impacts of testosterone in men and women

Ruth, Katherine S ; Day, Felix R ; Tyrrell, Jessica ; Thompson, Deborah J ; Wood, Andrew R ; Mahajan, Anubha ; Beaumont, Robin N ; Wittemans, Laura ; Martin, Susan ; Busch, Alexander S ; Erzurumluoglu, A Mesut ; Hollis, Benjamin ; O'Mara, Tracy A ; McCarthy, Mark I ; Langenberg, Claudia ; Easton, Douglas F ; Wareham, Nicholas J ; Burgess, Stephen ; Murray, Anna ; Ong, Ken K ; Frayling, Timothy M ; Perry, John R B

Nature medicine, 2020-02, Vol.26 (2), p.252-258 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants
CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants
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CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants

Carver, Tim ; Hartley, Simon ; Lee, Andrew ; Cunningham, Alex P ; Archer, Stephanie ; Babb de Villiers, Chantal ; Roberts, Jonathan ; Ruston, Rod ; Walter, Fiona M ; Tischkowitz, Marc ; Easton, Douglas F ; Antoniou, Antonis C

Cancer epidemiology, biomarkers & prevention, 2021-03, Vol.30 (3), p.469-473 [Periódico revisado por pares]

United States

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3
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study
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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

Copson, Ellen R ; Maishman, Tom C ; Tapper, Will J ; Cutress, Ramsey I ; Greville-Heygate, Stephanie ; Altman, Douglas G ; Eccles, Bryony ; Gerty, Sue ; Durcan, Lorraine T ; Jones, Louise ; Evans, D Gareth ; Thompson, Alastair M ; Pharoah, Paul ; Easton, Douglas F ; Dunning, Alison M ; Hanby, Andrew ; Lakhani, Sunil ; Eeles, Ros ; Gilbert, Fiona J ; Hamed, Hisham ; Hodgson, Shirley ; Simmonds, Peter ; Stanton, Louise ; Eccles, Diana M

The lancet oncology, 2018-02, Vol.19 (2), p.169-180 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE
Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE
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Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE

MAVADDAT, Nasim ; PEOCK, Susan ; DAVIDSON, Rosemarie ; ECCLES, Diana ; COLE, Trevor ; COOK, Jackie ; BREWER, Carole ; TISCHKOWITZ, Marc ; DOUGLAS, Fiona ; HODGSON, Shirley ; WALKER, Lisa ; PORTEOUS, Mary E ; FROST, Debra ; MORRISON, Patrick J ; SIDE, Lucy E ; KENNEDY, M. John ; HOUGHTON, Catherine ; DONALDSON, Alan ; ROGERS, Mark T ; DORKINS, Huw ; MIEDZYBRODZKA, Zosia ; GREGORY, Helen ; EASON, Jacqueline ; ELLIS, Steve ; BARWELL, Julian ; MCCANN, Emma ; MURRAY, Alex ; ANTONIOU, Antonis C ; EASTON, Douglas F ; PLATTE, Radka ; FINEBERG, Elena ; EVANS, D. Gareth ; IZATT, Louise ; EELES, Rosalind A ; ADLARD, Julian

JNCI : Journal of the National Cancer Institute, 2013-06, Vol.105 (11), p.812-822 [Periódico revisado por pares]

Cary, NC: Oxford University Press

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5
Comprehensive functional annotation of 77 prostate cancer risk loci
Comprehensive functional annotation of 77 prostate cancer risk loci
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Comprehensive functional annotation of 77 prostate cancer risk loci

Hazelett, Dennis J ; Rhie, Suhn Kyong ; Gaddis, Malaina ; Yan, Chunli ; Lakeland, Daniel L ; Coetzee, Simon G ; Henderson, Brian E ; Noushmehr, Houtan ; Cozen, Wendy ; Kote-Jarai, Zsofia ; Eeles, Rosalind A ; Easton, Douglas F ; Haiman, Christopher A ; Lu, Wange ; Farnham, Peggy J ; Coetzee, Gerhard A Cheung, Vivian G.

PLoS genetics, 2014-01, Vol.10 (1), p.e1004102 [Periódico revisado por pares]

United States: Public Library of Science

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6
Genetic susceptibility to breast cancer
Genetic susceptibility to breast cancer
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Genetic susceptibility to breast cancer

Mavaddat, Nasim ; Antoniou, Antonis C. ; Easton, Douglas F. ; Garcia-Closas, Montserrat

Molecular oncology, 2010-06, Vol.4 (3), p.174-191 [Periódico revisado por pares]

United States: Elsevier B.V

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7
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers
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Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

Zhang, Yan Dora ; Hurson, Amber N ; Zhang, Haoyu ; Choudhury, Parichoy Pal ; Easton, Douglas F ; Milne, Roger L ; Simard, Jacques ; Hall, Per ; Michailidou, Kyriaki ; Dennis, Joe ; Schmidt, Marjanka K ; Chang-Claude, Jenny ; Gharahkhani, Puya ; Whiteman, David ; Campbell, Peter T ; Hoffmeister, Michael ; Jenkins, Mark ; Peters, Ulrike ; Hsu, Li ; Gruber, Stephen B ; Casey, Graham ; Schmit, Stephanie L ; O'Mara, Tracy A ; Spurdle, Amanda B ; Thompson, Deborah J ; Tomlinson, Ian ; De Vivo, Immaculata ; Landi, Maria Teresa ; Law, Matthew H ; Iles, Mark M ; Demenais, Florence ; Kumar, Rajiv ; MacGregor, Stuart ; Bishop, D Timothy ; Ward, Sarah V ; Bondy, Melissa L ; Houlston, Richard ; Wiencke, John K ; Melin, Beatrice ; Barnholtz-Sloan, Jill ; Kinnersley, Ben ; Wrensch, Margaret R ; Amos, Christopher I ; Hung, Rayjean J ; Brennan, Paul ; McKay, James ; Caporaso, Neil E ; Berndt, Sonja I ; Birmann, Brenda M ; Camp, Nicola J ; Kraft, Peter ; Rothman, Nathaniel ; Slager, Susan L ; Berchuck, Andrew ; Pharoah, Paul D P ; Sellers, Thomas A ; Gayther, Simon A ; Pearce, Celeste L ; Goode, Ellen L ; Schildkraut, Joellen M ; Moysich, Kirsten B ; Amundadottir, Laufey T ; Jacobs, Eric J ; Klein, Alison P ; Petersen, Gloria M ; Risch, Harvey A ; Stolzenberg-Solomon, Rachel Z ; Wolpin, Brian M ; Li, Donghui ; Eeles, Rosalind A ; Haiman, Christopher A ; Kote-Jarai, Zsofia ; Schumacher, Fredrick R ; Al Olama, Ali Amin ; Purdue, Mark P ; Scelo, Ghislaine ; Dalgaard, Marlene D ; Greene, Mark H ; Grotmol, Tom ; Kanetsky, Peter A ; McGlynn, Katherine A ; Nathanson, Katherine L ; Turnbull, Clare ; Wiklund, Fredrik ; Chanock, Stephen J ; Chatterjee, Nilanjan ; Garcia-Closas, Montserrat

Nature communications, 2020-07, Vol.11 (1), p.3353-13, Article 3353 [Periódico revisado por pares]

England: Nature Publishing Group

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8
The contribution of rare variation to prostate cancer heritability
The contribution of rare variation to prostate cancer heritability
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The contribution of rare variation to prostate cancer heritability

Mancuso, Nicholas ; Rohland, Nadin ; Rand, Kristin A ; Tandon, Arti ; Allen, Alexander ; Quinque, Dominique ; Mallick, Swapan ; Li, Heng ; Stram, Alex ; Sheng, Xin ; Kote-Jarai, Zsofia ; Easton, Douglas F ; Eeles, Rosalind A ; Le Marchand, Loic ; Lubwama, Alex ; Stram, Daniel ; Watya, Stephen ; Conti, David V ; Henderson, Brian ; Haiman, Christopher A ; Pasaniuc, Bogdan ; Reich, David

Nature genetics, 2016-01, Vol.48 (1), p.30-35 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer
Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer
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Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer

Abubakar, Mustapha ; Figueroa, Jonine ; Ali, H Raza ; Blows, Fiona ; Lissowska, Jolanta ; Caldas, Carlos ; Easton, Douglas F ; Sherman, Mark E ; Garcia-Closas, Montserrat ; Dowsett, Mitch ; Pharoah, Paul D

Modern pathology, 2019-09, Vol.32 (9), p.1244-1256 [Periódico revisado por pares]

United States: Elsevier Limited

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10
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Duffy, David L ; Zhu, Gu ; Li, Xin ; Sanna, Marianna ; Iles, Mark M ; Jacobs, Leonie C ; Evans, David M ; Yazar, Seyhan ; Beesley, Jonathan ; Law, Matthew H ; Kraft, Peter ; Visconti, Alessia ; Taylor, John C ; Liu, Fan ; Wright, Margaret J ; Henders, Anjali K ; Bowdler, Lisa ; Glass, Dan ; Ikram, M Arfan ; Uitterlinden, André G ; Madden, Pamela A ; Heath, Andrew C ; Nelson, Elliot C ; Green, Adele C ; Chanock, Stephen ; Barrett, Jennifer H ; Brown, Matthew A ; Hayward, Nicholas K ; MacGregor, Stuart ; Sturm, Richard A ; Hewitt, Alex W ; Kayser, Manfred ; Hunter, David J ; Newton Bishop, Julia A ; Spector, Timothy D ; Montgomery, Grant W ; Mackey, David A ; Smith, George Davey ; Nijsten, Tamar E ; Bishop, D Timothy ; Bataille, Veronique ; Falchi, Mario ; Han, Jiali ; Martin, Nicholas G

Nature communications, 2018-11, Vol.9 (1), p.4774-10, Article 4774 [Periódico revisado por pares]

England: Nature Publishing Group

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