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Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
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Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

Shin, Donghyuk ; Mukherjee, Rukmini ; Grewe, Diana ; Bojkova, Denisa ; Baek, Kheewoong ; Bhattacharya, Anshu ; Schulz, Laura ; Widera, Marek ; Mehdipour, Ahmad Reza ; Tascher, Georg ; Geurink, Paul P ; Wilhelm, Alexander ; van der Heden van Noort, Gerbrand J ; Ovaa, Huib ; Müller, Stefan ; Knobeloch, Klaus-Peter ; Rajalingam, Krishnaraj ; Schulman, Brenda A ; Cinatl, Jindrich ; Hummer, Gerhard ; Ciesek, Sandra ; Dikic, Ivan

Nature (London), 2020-11, Vol.587 (7835), p.657-662 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity
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Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity

Shen, Zhengnan ; Ratia, Kiira ; Cooper, Laura ; Kong, Deyu ; Lee, Hyun ; Kwon, Youngjin ; Li, Yangfeng ; Alqarni, Saad ; Huang, Fei ; Dubrovskyi, Oleksii ; Rong, Lijun ; Thatcher, Gregory R J ; Xiong, Rui

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2940-2955 [Periódico revisado por pares]

United States

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3
A Dual‐Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain‐like Proteases of SARS‐CoV‐2‐Infected Cells for Accurate Detection and Rapid Inhibitor Screening
A Dual‐Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain‐like Proteases of SARS‐CoV‐2‐Infected Cells for Accurate Detection and Rapid Inhibitor Screening
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A Dual‐Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain‐like Proteases of SARS‐CoV‐2‐Infected Cells for Accurate Detection and Rapid Inhibitor Screening

Cheng, Yong ; Borum, Raina M. ; Clark, Alex E. ; Jin, Zhicheng ; Moore, Colman ; Fajtová, Pavla ; O'Donoghue, Anthony J. ; Carlin, Aaron F. ; Jokerst, Jesse V.

Angewandte Chemie (International ed.), 2022-02, Vol.61 (9), p.e202113617-n/a [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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4
Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2
Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2
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Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2

Weglarz-Tomczak, Ewelina ; Tomczak, Jakub M ; Talma, Michał ; Burda-Grabowska, Małgorzata ; Giurg, Mirosław ; Brul, Stanley

Scientific reports, 2021-02, Vol.11 (1), p.3640-3640, Article 3640 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Dampalla, Chamandi S ; Zheng, Jian ; Perera, Krishani Dinali ; Wong, Lok-Yin Roy ; Meyerholz, David K ; Nguyen, Harry Nhat ; Kashipathy, Maithri M ; Battaile, Kevin P ; Lovell, Scott ; Kim, Yunjeong ; Perlman, Stanley ; Groutas, William C ; Chang, Kyeong-Ok

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Molecular docking of potential SARS-CoV-2 papain-like protease inhibitors
Molecular docking of potential SARS-CoV-2 papain-like protease inhibitors
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Molecular docking of potential SARS-CoV-2 papain-like protease inhibitors

Li, Daoqun ; Luan, Junwen ; Zhang, Leiliang

Biochemical and biophysical research communications, 2021-01, Vol.538, p.72-79 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Tomatidine and Patchouli Alcohol as Inhibitors of SARS-CoV-2 Enzymes (3CLpro, PLpro and NSP15) by Molecular Docking and Molecular Dynamics Simulations
Tomatidine and Patchouli Alcohol as Inhibitors of SARS-CoV-2 Enzymes (3CLpro, PLpro and NSP15) by Molecular Docking and Molecular Dynamics Simulations
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Tomatidine and Patchouli Alcohol as Inhibitors of SARS-CoV-2 Enzymes (3CLpro, PLpro and NSP15) by Molecular Docking and Molecular Dynamics Simulations

Zrieq, Rafat ; Ahmad, Iqrar ; Snoussi, Mejdi ; Noumi, Emira ; Iriti, Marcello ; Algahtani, Fahad D ; Patel, Harun ; Saeed, Mohd ; Tasleem, Munazzah ; Sulaiman, Shadi ; Aouadi, Kaïss ; Kadri, Adel

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10693 [Periódico revisado por pares]

Switzerland: MDPI AG

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8
Identification of potential plant-based inhibitor against viral proteases of SARS-CoV-2 through molecular docking, MM-PBSA binding energy calculations and molecular dynamics simulation
Identification of potential plant-based inhibitor against viral proteases of SARS-CoV-2 through molecular docking, MM-PBSA binding energy calculations and molecular dynamics simulation
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Identification of potential plant-based inhibitor against viral proteases of SARS-CoV-2 through molecular docking, MM-PBSA binding energy calculations and molecular dynamics simulation

Gogoi, Bhaskarjyoti ; Chowdhury, Purvita ; Goswami, Nabajyoti ; Gogoi, Neelutpal ; Naiya, Tufan ; Chetia, Pankaj ; Mahanta, Saurov ; Chetia, Dipak ; Tanti, Bhaben ; Borah, Probodh ; Handique, Pratap Jyoti

Molecular diversity, 2021-08, Vol.25 (3), p.1963-1977 [Periódico revisado por pares]

Cham: Springer International Publishing

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9
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease

Lim, Chew Theng ; Tan, Kang Wei ; Wu, Mary ; Ulferts, Rachel ; Armstrong, Lee A ; Ozono, Eiko ; Drury, Lucy S ; Milligan, Jennifer C ; Zeisner, Theresa U ; Zeng, Jingkun ; Weissmann, Florian ; Canal, Berta ; Bineva-Todd, Ganka ; Howell, Michael ; O'Reilly, Nicola ; Beale, Rupert ; Kulathu, Yogesh ; Labib, Karim ; Diffley, John F X

Biochemical journal, 2021-07, Vol.478 (13), p.2517-2531 [Periódico revisado por pares]

England: Portland Press Ltd

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10
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
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Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Tan, Bin ; Zhang, Xiaoming ; Ansari, Ahmadullah ; Jadhav, Prakash ; Tan, Haozhou ; Li, Kan ; Chopra, Ashima ; Ford, Alexandra ; Chi, Xiang ; Ruiz, Francesc Xavier ; Arnold, Eddy ; Deng, Xufang ; Wang, Jun

Science (American Association for the Advancement of Science), 2024-03, Vol.383 (6690), p.1434-1440 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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