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Material Type: Artigo
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The hypocretin/orexin system mediates the extinction of fear memoriesFlores, África ; Valls-Comamala, Victòria ; Costa, Giulia ; Saravia, Rocío ; Maldonado, Rafael ; Berrendero, FernandoNeuropsychopharmacology (New York, N.Y.), 2014-11, Vol.39 (12), p.2732-2741 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipientsLunde, Ingrid ; Bremer, Sara ; Midtvedt, Karsten ; Mohebi, Beata ; Dahl, Miriam ; Bergan, Stein ; Åsberg, Anders ; Christensen, HegeEuropean journal of clinical pharmacology, 2014-06, Vol.70 (6), p.685-693 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Variability in Loss of Multiple Enzyme Activities Due to the Human Genetic Variation P284T Located in the Flexible Hinge Region of NADPH Cytochrome P450 OxidoreductaseParween, Shaheena ; Rojas Velazquez, Maria Natalia ; Udhane, Sameer S. ; Kagawa, Norio ; Pandey, Amit V.Frontiers in pharmacology, 2019-10, Vol.10, p.1187-1187 [Periódico revisado por pares]Frontiers Media S.ATexto completo disponível |
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Material Type: Artigo
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A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson's diseaseHartz, Philip ; Fehlmann, Tobias ; Wagenpfeil, Gudrun ; Unger, Marcus Michael ; Bernhardt, RitaFrontiers in pharmacology, 2023-01, Vol.13, p.1094265-1094265 [Periódico revisado por pares]Switzerland: Frontiers Media S.ATexto completo disponível |
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Material Type: Artigo
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SNPs in cytochrome P450 genes decide on the fate of individuals with genetic predisposition to Parkinson’s diseasePetkova-Kirova, Polina ; Baas, Stephan ; Wagenpfeil, Gudrun ; Hartz, Philip ; Unger, Marcus Michael ; Bernhardt, RitaFrontiers in pharmacology, 2023-08, Vol.14, p.1244516-1244516 [Periódico revisado por pares]Frontiers Media S.ATexto completo disponível |
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Material Type: Artigo
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Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, FunctionPandey, Amit V ; Henderson, Colin J ; Ishii, Yuji ; Kranendonk, Michel ; Backes, Wayne L ; Zanger, Ulrich MFrontiers in pharmacology, 2017-11, Vol.8, p.881 [Periódico revisado por pares]Switzerland: Frontiers Media S.ATexto completo disponível |
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Material Type: Artigo
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Variability of voriconazole concentrations in patients with hematopoietic stem cell transplantation and hematological malignancies: influence of loading dose, procalcitonin, and pregnane X receptor polymorphismsZeng, Guangting ; Wang, Linlin ; Shi, Lihong ; Li, Huilan ; Zhu, Miaomiao ; Luo, Jia ; Zhang, ZanlingEuropean journal of clinical pharmacology, 2020-04, Vol.76 (4), p.515-523 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Impact of POR28 Variant on Tacrolimus Pharmacokinetics in Kidney Transplant Patients with Different CYP3A5 GenotypesJanaina B. F. Everton ; Fernando J. B. Patrício ; Manuel S. Faria ; Teresa C. A. Ferreira ; Natalino Salgado Filho ; Gyl E.B. Silva ; Elen A. Romão ; Marcelo MagalhãesCurrent drug metabolism, 2022-01, Vol.23 (3), p.233-241 [Periódico revisado por pares]Sharjah: Bentham Science Publishers LtdTexto completo disponível |
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Material Type: Artigo
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Cytochrome P450 oxidoreductase genetic polymorphisms A503V and rs2868177 do not significantly affect warfarin stable dosage in Han-Chinese patients with mechanical heart valve replacementTan, Sheng-Lan ; Li, Zhi ; Zhang, Wei ; Song, Guo-Bao ; Liu, Li-Ming ; Peng, Juan ; Liu, Zhao-Qian ; Fan, Lan ; Meng, Xiang-Guang ; Wang, Lian-Sheng ; Chen, Yao ; Zhou, Xin-Min ; Zhou, Hong-HaoEuropean journal of clinical pharmacology, 2013-10, Vol.69 (10), p.1769-1775 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 OxidoreductaseUdhane, Sameer S ; Parween, Shaheena ; Kagawa, Norio ; Pandey, Amit VFrontiers in pharmacology, 2017-08, Vol.8, p.580 [Periódico revisado por pares]Switzerland: Frontiers Media S.ATexto completo disponível |