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Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist
Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist
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Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist

Hagan, Jim J ; Price, Gary W ; Jeffrey, Phillip ; Deeks, Nigel J ; Stean, Tania ; Piper, David ; Smith, Martin I ; Upton, Neil ; Medhurst, Andrew D ; Middlemiss, Derek N ; Riley, Graham J ; Lovell, Peter J ; Bromidge, Steven M ; Thomas, David R

British journal of pharmacology, 2000-06, Vol.130 (3), p.539-548 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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2
Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796):  A Potent and Selective Dopamine D3 Receptor Antagonist
Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796):  A Potent and Selective Dopamine D3 Receptor Antagonist
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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796):  A Potent and Selective Dopamine D3 Receptor Antagonist

Macdonald, Gregor J ; Branch, Clive L ; Hadley, Michael S ; Johnson, Christopher N ; Nash, David J ; Smith, Alexander B ; Stemp, Geoffrey ; Thewlis, Kevin M ; Vong, Antonio K. K ; Austin, Nigel E ; Jeffrey, Phillip ; Winborn, Kim Y ; Boyfield, Izzy ; Hagan, Jim J ; Middlemiss, Derek N ; Reavill, Charlie ; Riley, Graham J ; Watson, Jeannette M ; Wood, Martyn ; Parker, Steve G ; Ashby, Charles R

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4952-4964 [Periódico revisado por pares]

United States: American Chemical Society

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3
Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats
Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats
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Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats

Vorel, Stanislav R ; Ashby, Charles R., Jr ; Paul, Mousumi ; Liu, Xinhe ; Hayes, Robert ; Hagan, Jim J ; Middlemiss, Derek N ; Stemp, Geoffrey ; Gardner, Eliot L

The Journal of neuroscience, 2002-11, Vol.22 (21), p.9595-9603 [Periódico revisado por pares]

United States: Soc Neuroscience

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4
Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone
Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone
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Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodone

HUGHES, Zoë A ; STARR, Kathryn R ; LANGMEAD, Christopher J ; HILL, Matthew ; BARTOSZYK, Gerd D ; HAGAN, James J ; MIDDLEMISS, Derek N ; DAWSON, Lee A

European journal of pharmacology, 2005-03, Vol.510 (1-2), p.49-57 [Periódico revisado por pares]

Amsterdam: Elsevier

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5
Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry
Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry
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Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry

Wood, Martyn D ; Murkitt, Karen L ; Ho, Michael ; Watson, Jeannette M ; Brown, Frank ; Hunter, A Jacqueline ; Middlemiss, Derek N

British journal of pharmacology, 1999-04, Vol.126 (7), p.1620-1624 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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6
Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR
Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR
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Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR

MEDHURST, Andrew D ; LEZOUALC'H, Frank ; FISCHMEISTER, Rodolphe ; MIDDLEMISS, Derek N ; SANGER, Gareth J

Brain research. Molecular brain research., 2001-06, Vol.90 (2), p.125-134 [Periódico revisado por pares]

Amsterdam: Elsevier

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7
SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in rats
SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in rats
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SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in rats

Thomas, David R ; Melotto, Sergio ; Massagrande, Mario ; Gribble, Andrew D ; Jeffrey, Phillip ; Stevens, Alexander J ; Deeks, Nigel J ; Eddershaw, Peter J ; Fenwick, Susan H ; Riley, Graham ; Stean, Tania ; Scott, Claire M ; Hill, Matthew J ; Middlemiss, Derek N ; Hagan, Jim J ; Price, Gary W ; Forbes, Ian T

British journal of pharmacology, 2003-06, Vol.139 (4), p.705-714 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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8
A Novel, Potent, and Selective 5-HT7 Antagonist:  (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
A Novel, Potent, and Selective 5-HT7 Antagonist:  (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
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A Novel, Potent, and Selective 5-HT7 Antagonist:  (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)

Lovell, Peter J ; Bromidge, Steven M ; Dabbs, Steven ; Duckworth, D. Malcolm ; Forbes, Ian T ; Jennings, Andrew J ; King, Frank D ; Middlemiss, Derek N ; Rahman, Shirley K ; Saunders, Damian V ; Collin, Lissa L ; Hagan, Jim J ; Riley, Graham J ; Thomas, David R

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.342-345 [Periódico revisado por pares]

American Chemical Society

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9
Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist
Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist
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Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist

Routledge, Carol ; Bromidge, Steven M ; Moss, Stephen F ; Price, Gary W ; Hirst, Warren ; Newman, Helen ; Riley, Graham ; Gager, Tracey ; Stean, Tania ; Upton, Neil ; Clarke, Stephen E ; Brown, Anthony M ; Middlemiss, Derek N

British journal of pharmacology, 2000-08, Vol.130 (7), p.1606-1612 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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10
Serotonergic targets in depression
Serotonergic targets in depression
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Serotonergic targets in depression

Middlemiss, Derek N ; Price, Gary W ; Watson, Jeannette M

Current Opinion in Pharmacology, 2002-02, Vol.2 (1), p.18-22 [Periódico revisado por pares]

England: Elsevier Ltd

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