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1 |
Material Type: Artigo
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Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonistHagan, Jim J ; Price, Gary W ; Jeffrey, Phillip ; Deeks, Nigel J ; Stean, Tania ; Piper, David ; Smith, Martin I ; Upton, Neil ; Medhurst, Andrew D ; Middlemiss, Derek N ; Riley, Graham J ; Lovell, Peter J ; Bromidge, Steven M ; Thomas, David RBritish journal of pharmacology, 2000-06, Vol.130 (3), p.539-548 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor AntagonistMacdonald, Gregor J ; Branch, Clive L ; Hadley, Michael S ; Johnson, Christopher N ; Nash, David J ; Smith, Alexander B ; Stemp, Geoffrey ; Thewlis, Kevin M ; Vong, Antonio K. K ; Austin, Nigel E ; Jeffrey, Phillip ; Winborn, Kim Y ; Boyfield, Izzy ; Hagan, Jim J ; Middlemiss, Derek N ; Reavill, Charlie ; Riley, Graham J ; Watson, Jeannette M ; Wood, Martyn ; Parker, Steve G ; Ashby, Charles RJournal of medicinal chemistry, 2003-11, Vol.46 (23), p.4952-4964 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in RatsVorel, Stanislav R ; Ashby, Charles R., Jr ; Paul, Mousumi ; Liu, Xinhe ; Hayes, Robert ; Hagan, Jim J ; Middlemiss, Derek N ; Stemp, Geoffrey ; Gardner, Eliot LThe Journal of neuroscience, 2002-11, Vol.22 (21), p.9595-9603 [Periódico revisado por pares]United States: Soc NeuroscienceTexto completo disponível |
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Material Type: Artigo
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Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/ serotonin reuptake inhibitor, vilazodoneHUGHES, Zoë A ; STARR, Kathryn R ; LANGMEAD, Christopher J ; HILL, Matthew ; BARTOSZYK, Gerd D ; HAGAN, James J ; MIDDLEMISS, Derek N ; DAWSON, Lee AEuropean journal of pharmacology, 2005-03, Vol.510 (1-2), p.49-57 [Periódico revisado por pares]Amsterdam: ElsevierTexto completo disponível |
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Material Type: Artigo
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Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometryWood, Martyn D ; Murkitt, Karen L ; Ho, Michael ; Watson, Jeannette M ; Brown, Frank ; Hunter, A Jacqueline ; Middlemiss, Derek NBritish journal of pharmacology, 1999-04, Vol.126 (7), p.1620-1624 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCRMEDHURST, Andrew D ; LEZOUALC'H, Frank ; FISCHMEISTER, Rodolphe ; MIDDLEMISS, Derek N ; SANGER, Gareth JBrain research. Molecular brain research., 2001-06, Vol.90 (2), p.125-134 [Periódico revisado por pares]Amsterdam: ElsevierTexto completo disponível |
7 |
Material Type: Artigo
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SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in ratsThomas, David R ; Melotto, Sergio ; Massagrande, Mario ; Gribble, Andrew D ; Jeffrey, Phillip ; Stevens, Alexander J ; Deeks, Nigel J ; Eddershaw, Peter J ; Fenwick, Susan H ; Riley, Graham ; Stean, Tania ; Scott, Claire M ; Hill, Matthew J ; Middlemiss, Derek N ; Hagan, Jim J ; Price, Gary W ; Forbes, Ian TBritish journal of pharmacology, 2003-06, Vol.139 (4), p.705-714 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
8 |
Material Type: Artigo
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A Novel, Potent, and Selective 5-HT7 Antagonist: (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)Lovell, Peter J ; Bromidge, Steven M ; Dabbs, Steven ; Duckworth, D. Malcolm ; Forbes, Ian T ; Jennings, Andrew J ; King, Frank D ; Middlemiss, Derek N ; Rahman, Shirley K ; Saunders, Damian V ; Collin, Lissa L ; Hagan, Jim J ; Riley, Graham J ; Thomas, David RJournal of medicinal chemistry, 2000-02, Vol.43 (3), p.342-345 [Periódico revisado por pares]American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonistRoutledge, Carol ; Bromidge, Steven M ; Moss, Stephen F ; Price, Gary W ; Hirst, Warren ; Newman, Helen ; Riley, Graham ; Gager, Tracey ; Stean, Tania ; Upton, Neil ; Clarke, Stephen E ; Brown, Anthony M ; Middlemiss, Derek NBritish journal of pharmacology, 2000-08, Vol.130 (7), p.1606-1612 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Serotonergic targets in depressionMiddlemiss, Derek N ; Price, Gary W ; Watson, Jeannette MCurrent Opinion in Pharmacology, 2002-02, Vol.2 (1), p.18-22 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |