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Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy‐mediated drug resistance in ovarian cancer cells, xenografts, and patient‐derived xenograft models
Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy‐mediated drug resistance in ovarian cancer cells, xenografts, and patient‐derived xenograft models
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Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy‐mediated drug resistance in ovarian cancer cells, xenografts, and patient‐derived xenograft models

Santiago‐O’Farrill, Janice M. ; Weroha, S. John ; Hou, Xiaonan ; Oberg, Ann L. ; Heinzen, Ethan P. ; Maurer, Matthew J. ; Pang, Lan ; Rask, Philip ; Amaravadi, Ravi K. ; Becker, Sarah E. ; Romero, Ignacio ; Rubio, Ma Jesús ; Matias‐Guiu, Xavier ; Santacana, Maria ; Llombart‐Cussac, Antonio ; Poveda, Andrés ; Lu, Zhen ; Bast, Robert C.

Cancer, 2020-02, Vol.126 (4), p.894-907 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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2
SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers
SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers
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SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers

Lu, Zhen ; Mao, Weiqun ; Yang, Hailing ; Santiago-O'Farrill, Janice M ; Rask, Philip J ; Mondal, Jayanta ; Chen, Hu ; Ivan, Cristina ; Liu, Xiuping ; Liu, Chang-Gong ; Xi, Yuanxin ; Masuda, Kenta ; Carrami, Eli M ; Chen, Meng ; Tang, Yitao ; Pang, Lan ; Lakomy, David S ; Calin, George A ; Liang, Han ; Ahmed, Ahmed A ; Vankayalapati, Hariprasad ; Bast, Jr, Robert C

The Journal of clinical investigation, 2022-06, Vol.132 (11), p.1-20 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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3
Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition
Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition
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Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition

Blessing, Alicia M. ; Santiago‐O'Farrill, Janice M. ; Mao, Weiqun ; Pang, Lan ; Ning, Jing ; Pak, Daewoo ; Bollu, Lakshmi Reddy ; Rask, Philip ; Iles, LaKesla ; Yang, Hailing ; Tran, Samantha ; Elmir, Ezzeddine ; Bartholomeusz, Geoffrey ; Langley, Robert ; Lu, Zhen ; Bast, Robert C.

Cancer, 2020-08, Vol.126 (15), p.3579-3592 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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4
A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel
A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel
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A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel

Zhou, Jinhua ; Alfraidi, Albandri ; Zhang, Shu ; Santiago-O'Farrill, Janice M ; Yerramreddy Reddy, Venkata Krishna ; Alsaadi, Abdulkhaliq ; Ahmed, Ahmed A ; Yang, Hailing ; Liu, Jinsong ; Mao, Weiqun ; Wang, Yan ; Takemori, Hiroshi ; Vankayalapati, Hariprasad ; Lu, Zhen ; Bast, Jr, Robert C

Clinical cancer research, 2017-04, Vol.23 (8), p.1945-1954 [Periódico revisado por pares]

United States: American Association for Cancer Research Inc

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5
Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia
Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia
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Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia

Timofeeva, Natalia ; Ayres, Mary L ; Baran, Natalia ; Santiago-O'Farrill, Janice M ; Bildik, Gamze ; Lu, Zhen ; Konopleva, Marina ; Gandhi, Varsha

Frontiers in oncology, 2023-05, Vol.13, p.1161254-1161254 [Periódico revisado por pares]

Switzerland: Frontiers Media S.A

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6
Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia
Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia
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Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia

Irwin, Mary E ; Nelson, Laura D ; Santiago-O'Farrill, Janice M ; Knouse, Phillip D ; Miller, Claudia P ; Palla, Shana L ; Siwak, Doris R ; Mills, Gordon B ; Estrov, Zeev ; Li, Shulin ; Kornblau, Steven M ; Hughes, Dennis P ; Chandra, Joya Tan, Ming

PloS one, 2013-08, Vol.8 (8), p.e70608 [Periódico revisado por pares]

United States: Public Library of Science

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7
Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy
Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy
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Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy

Santiago-O'Farrill, Janice M ; Kleinerman, Eugenie S ; Hollomon, Mario G ; Livingston, Andrew ; Wang, Wei-Lien ; Tsai, Jen-Wei ; Gordon, Nancy B

Oncotarget, 2018-01, Vol.9 (2), p.1602-1616

United States: Impact Journals LLC

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8
Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells
Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells
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Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells

Hollomon, Mario G ; Gordon, Nancy ; Santiago-O'Farrill, Janice M ; Kleinerman, Eugenie S

BMC cancer, 2013-10, Vol.13 (1), p.500-500, Article 500 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
Crizotinib enhances PARP inhibitor efficacy in ovarian cancer cells and xenograft models by inducing autophagy
Crizotinib enhances PARP inhibitor efficacy in ovarian cancer cells and xenograft models by inducing autophagy
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Crizotinib enhances PARP inhibitor efficacy in ovarian cancer cells and xenograft models by inducing autophagy

Santiago-O'Farrill, Janice M ; Blessing Bollu, Alicia ; Yang, Hailing ; Orellana, Vivian ; Pina, Marc ; Zhang, Xudong ; Liu, Jinsong ; Bast, Robert C ; Lu, Zhen

Molecular cancer research, 2024-05, p.OF1-OF12 [Periódico revisado por pares]

United States

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10
Abstract 4083: Crizotinib improves the therapeutic efficacy of olaparib in ovarian cancer
Abstract 4083: Crizotinib improves the therapeutic efficacy of olaparib in ovarian cancer
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Abstract 4083: Crizotinib improves the therapeutic efficacy of olaparib in ovarian cancer

Santiago-O'Farrill, Janice M. ; Blessing, Alicia M. ; Becker, Sarah E. ; Lu, Zhen ; Bast, Robert C.

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4083-4083 [Periódico revisado por pares]

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