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Material Type: Artigo
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Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanomaLiu, David ; Schilling, Bastian ; Liu, Derek ; Sucker, Antje ; Livingstone, Elisabeth ; Jerby-Arnon, Livnat ; Zimmer, Lisa ; Gutzmer, Ralf ; Satzger, Imke ; Loquai, Carmen ; Grabbe, Stephan ; Vokes, Natalie ; Margolis, Claire A ; Conway, Jake ; He, Meng Xiao ; Elmarakeby, Haitham ; Dietlein, Felix ; Miao, Diana ; Tracy, Adam ; Gogas, Helen ; Goldinger, Simone M ; Utikal, Jochen ; Blank, Christian U ; Rauschenberg, Ricarda ; von Bubnoff, Dagmar ; Krackhardt, Angela ; Weide, Benjamin ; Haferkamp, Sebastian ; Kiecker, Felix ; Izar, Ben ; Garraway, Levi ; Regev, Aviv ; Flaherty, Keith ; Paschen, Annette ; Van Allen, Eliezer M ; Schadendorf, DirkNature medicine, 2019-12, Vol.25 (12), p.1916-1927 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Resistance to checkpoint blockade therapy through inactivation of antigen presentationSade-Feldman, Moshe ; Jiao, Yunxin J ; Chen, Jonathan H ; Rooney, Michael S ; Barzily-Rokni, Michal ; Eliane, Jean-Pierre ; Bjorgaard, Stacey L ; Hammond, Marc R ; Vitzthum, Hans ; Blackmon, Shauna M ; Frederick, Dennie T ; Hazar-Rethinam, Mehlika ; Nadres, Brandon A ; Van Seventer, Emily E ; Shukla, Sachet A ; Yizhak, Keren ; Ray, John P ; Rosebrock, Daniel ; Livitz, Dimitri ; Adalsteinsson, Viktor ; Getz, Gad ; Duncan, Lyn M ; Li, Bo ; Corcoran, Ryan B ; Lawrence, Donald P ; Stemmer-Rachamimov, Anat ; Boland, Genevieve M ; Landau, Dan A ; Flaherty, Keith T ; Sullivan, Ryan J ; Hacohen, NirNature communications, 2017-10, Vol.8 (1), p.1136-11, Article 1136 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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An intra-tumoral niche maintains and differentiates stem-like CD8 T cellsJansen, Caroline S ; Prokhnevska, Nataliya ; Master, Viraj A ; Sanda, Martin G ; Carlisle, Jennifer W ; Bilen, Mehmet Asim ; Cardenas, Maria ; Wilkinson, Scott ; Lake, Ross ; Sowalsky, Adam G ; Valanparambil, Rajesh M ; Hudson, William H ; McGuire, Donald ; Melnick, Kevin ; Khan, Amir I ; Kim, Kyu ; Chang, Yun Min ; Kim, Alice ; Filson, Christopher P ; Alemozaffar, Mehrdad ; Osunkoya, Adeboye O ; Mullane, Patrick ; Ellis, Carla ; Akondy, Rama ; Im, Se Jin ; Kamphorst, Alice O ; Reyes, Adriana ; Liu, Yuan ; Kissick, HaydnNature (London), 2019-12, Vol.576 (7787), p.465-470 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy targetManguso, Robert T ; Pope, Hans W ; Zimmer, Margaret D ; Brown, Flavian D ; Yates, Kathleen B ; Miller, Brian C ; Collins, Natalie B ; Bi, Kevin ; LaFleur, Martin W ; Juneja, Vikram R ; Weiss, Sarah A ; Lo, Jennifer ; Fisher, David E ; Miao, Diana ; Van Allen, Eliezer ; Root, David E ; Sharpe, Arlene H ; Doench, John G ; Haining, W NicholasNature (London), 2017-07, Vol.547 (7664), p.413-418 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinomaBraun, David A ; Hou, Yue ; Bakouny, Ziad ; Ficial, Miriam ; Sant' Angelo, Miriam ; Forman, Juliet ; Ross-Macdonald, Petra ; Berger, Ashton C ; Jegede, Opeyemi A ; Elagina, Liudmilla ; Steinharter, John ; Sun, Maxine ; Wind-Rotolo, Megan ; Pignon, Jean-Christophe ; Cherniack, Andrew D ; Lichtenstein, Lee ; Neuberg, Donna ; Catalano, Paul ; Freeman, Gordon J ; Sharpe, Arlene H ; McDermott, David F ; Van Allen, Eliezer M ; Signoretti, Sabina ; Wu, Catherine J ; Shukla, Sachet A ; Choueiri, Toni KNature medicine, 2020-06, Vol.26 (6), p.909-918 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Identification of essential genes for cancer immunotherapyPatel, Shashank J ; Sanjana, Neville E ; Kishton, Rigel J ; Eidizadeh, Arash ; Vodnala, Suman K ; Cam, Maggie ; Gartner, Jared J ; Jia, Li ; Steinberg, Seth M ; Yamamoto, Tori N ; Merchant, Anand S ; Mehta, Gautam U ; Chichura, Anna ; Shalem, Ophir ; Tran, Eric ; Eil, Robert ; Sukumar, Madhusudhanan ; Guijarro, Eva Perez ; Day, Chi-Ping ; Robbins, Paul ; Feldman, Steve ; Merlino, Glenn ; Zhang, Feng ; Restifo, Nicholas PNature (London), 2017-08, Vol.548 (7669), p.537-542 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Genomic correlates of response to immune checkpoint blockadeKeenan, Tanya E ; Burke, Kelly P ; Van Allen, Eliezer MNature medicine, 2019-03, Vol.25 (3), p.389-402 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor MicroenvironmentIida, Noriho ; Dzutsev, Amiran ; Stewart, C. Andrew ; Smith, Loretta ; Bouladoux, Nicolas ; Weingarten, Rebecca A. ; Molina, Daniel A. ; Salcedo, Rosalba ; Back, Timothy ; Cramer, Sarah ; Dai, Ren-Ming ; Kiu, Hiu ; Cardone, Marco ; Naik, Shruti ; Patri, Anil K. ; Wang, Ena ; Marincola, Francesco M. ; Frank, Karen M. ; Belkaid, Yasmine ; Trinchieri, Giorgio ; Goldszmid, Romina S.Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6161), p.967-970 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentationGermic, Nina ; Frangez, Ziva ; Yousefi, Shida ; Simon, Hans-UweCell death and differentiation, 2019-03, Vol.26 (4), p.715-727 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Disease-specific oligodendrocyte lineage cells arise in multiple sclerosisFalcão, Ana Mendanha ; van Bruggen, David ; Marques, Sueli ; Meijer, Mandy ; Jäkel, Sarah ; Agirre, Eneritz ; Samudyata ; Floriddia, Elisa M ; Vanichkina, Darya P ; Ffrench-Constant, Charles ; Williams, Anna ; Guerreiro-Cacais, André Ortlieb ; Castelo-Branco, GonçaloNature medicine, 2018-12, Vol.24 (12), p.1837-1844 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |