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Material Type: Artigo
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P-glycoprotein, FK-binding Protein-12, and the Intracellular Tacrolimus Concentration in T-lymphocytes and Monocytes of Kidney Transplant RecipientsUdomkarnjananun, Suwasin ; Francke, Marith I ; Dieterich, Marjolein ; van De Velde, Daan ; Litjens, Nicolle H R ; Boer, Karin ; De Winter, Brenda C M ; Baan, Carla C ; Hesselink, Dennis ATransplantation, 2023-02, Vol.107 (2), p.382-391 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Obesity-Induced Cellular Senescence Drives Anxiety and Impairs NeurogenesisOgrodnik, Mikolaj ; Zhu, Yi ; Langhi, Larissa G.P. ; Tchkonia, Tamar ; Krüger, Patrick ; Fielder, Edward ; Victorelli, Stella ; Ruswhandi, Rifqha A. ; Giorgadze, Nino ; Pirtskhalava, Tamar ; Podgorni, Oleg ; Enikolopov, Grigori ; Johnson, Kurt O. ; Xu, Ming ; Inman, Christine ; Palmer, Allyson K. ; Schafer, Marissa ; Weigl, Moritz ; Ikeno, Yuji ; Burns, Terry C. ; Passos, João F. ; von Zglinicki, Thomas ; Kirkland, James L. ; Jurk, DianaCell metabolism, 2019-05, Vol.29 (5), p.1061-1077.e8 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agentsJuvvadi, Praveen R ; Fox, 3rd, David ; Bobay, Benjamin G ; Hoy, Michael J ; Gobeil, Sophie M C ; Venters, Ronald A ; Chang, Zanetta ; Lin, Jackie J ; Averette, Anna Floyd ; Cole, D Christopher ; Barrington, Blake C ; Wheaton, Joshua D ; Ciofani, Maria ; Trzoss, Michael ; Li, Xiaoming ; Lee, Soo Chan ; Chen, Ying-Lien ; Mutz, Mitchell ; Spicer, Leonard D ; Schumacher, Maria A ; Heitman, Joseph ; Steinbach, William JNature communications, 2019-09, Vol.10 (1), p.4275-18, Article 4275 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Calcineurin inhibitors: 40 years later, can't live withoutAzzi, Jamil R ; Sayegh, Mohamed H ; Mallat, Samir GThe Journal of immunology (1950), 2013-12, Vol.191 (12), p.5785-5791 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic painYu, Xiaobing ; Liu, Hongju ; Hamel, Katherine A ; Morvan, Maelig G ; Yu, Stephen ; Leff, Jacqueline ; Guan, Zhonghui ; Braz, Joao M ; Basbaum, Allan INature communications, 2020-01, Vol.11 (1), p.264-264, Article 264 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Propagation of conformational instability in FK506-binding protein FKBP12LeMaster, David M. ; Bashir, Qamar ; Hernández, GriseldaBiochimica et biophysica acta. Proteins and proteomics, 2024-05, Vol.1872 (3), p.140990-140990, Article 140990 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophyMina, Erica ; Wyart, Elisabeth ; Sartori, Roberta ; Angelino, Elia ; Zaggia, Ivan ; Rausch, Valentina ; Maldotti, Mara ; Pagani, Alessia ; Hsu, Myriam Y ; Friziero, Alberto ; Sperti, Cosimo ; Menga, Alessio ; Graziani, Andrea ; Hirsch, Emilio ; Oliviero, Salvatore ; Sandri, Marco ; Conti, Laura ; Kautz, Léon ; Silvestri, Laura ; Porporato, Paolo ECell reports. Medicine, 2023-12, Vol.4 (12), p.101306-101306, Article 101306 [Periódico revisado por pares]United States: Cell PressTexto completo disponível |
8 |
Material Type: Artigo
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BK Polyomavirus Replication in Renal Tubular Epithelial Cells Is Inhibited by Sirolimus, but Activated by Tacrolimus Through a Pathway Involving FKBP‐12Hirsch, H. H. ; Yakhontova, K. ; Lu, M. ; Manzetti, J.American journal of transplantation, 2016-03, Vol.16 (3), p.821-832 [Periódico revisado por pares]United States: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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The Role of Pharmacogenetics in the Disposition of and Response to Tacrolimus in Solid Organ TransplantationHesselink, Dennis A. ; Bouamar, Rachida ; Elens, Laure ; van Schaik, Ron H. N. ; van Gelder, TeunClinical pharmacokinetics, 2014-02, Vol.53 (2), p.123-139 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
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Material Type: Artigo
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Generation of Bioactivity‐Tailored FK506/FK520 Analogs by CRISPR Editing in Streptomyces tsukubaensisBuntin, Kathrin ; Mrak, Peter ; Pivk Lukančič, Petra ; Wollbrett, Séverine ; Drčar, Tjasa ; Krastel, Philipp ; Thibaut, Christian ; Salcius, Michael ; Gao, Xiaolin ; Wang, Shaowen ; Weber, Eric ; Koplan, Eva ; Regenass, HugoChemistry : a European journal, 2024-01, Vol.30 (3), p.e202302350-n/a [Periódico revisado por pares]Germany: Wiley Subscription Services, IncTexto completo disponível |