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1
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Material Type:
Artigo
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Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Harris, Isaac S. ; Treloar, Aislinn E. ; Inoue, Satoshi ; Sasaki, Masato ; Gorrini, Chiara ; Lee, Kim Chung ; Yung, Ka Yi ; Brenner, Dirk ; Knobbe-Thomsen, Christiane B. ; Cox, Maureen A. ; Elia, Andrew ; Berger, Thorsten ; Cescon, David W. ; Adeoye, Adewunmi ; Brüstle, Anne ; Molyneux, Sam D. ; Mason, Jacqueline M. ; Li, Wanda Y. ; Yamamoto, Kazuo ; Wakeham, Andrew ; Berman, Hal K. ; Khokha, Rama ; Done, Susan J. ; Kavanagh, Terrance J. ; Lam, Ching-Wan ; Mak, Tak W.

Cancer cell, 2015-02, Vol.27 (2), p.211-222 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis
Material Type:
Artigo
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Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

Murthy, Aditya ; Shao, Yang Washington ; Narala, Swami R. ; Molyneux, Sam D. ; Zúñiga-Pflücker, Juan Carlos ; Khokha, Rama

Immunity (Cambridge, Mass.), 2012-01, Vol.36 (1), p.105-119 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state
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Artigo
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Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

Shimoda, Masayuki ; Principe, Simona ; Jackson, Hartland W ; Luga, Valbona ; Fang, Hui ; Molyneux, Sam D ; Shao, Yang W ; Aiken, Alison ; Waterhouse, Paul D ; Karamboulas, Christina ; Hess, Franz M ; Ohtsuka, Takashi ; Okada, Yasunori ; Ailles, Laurie ; Ludwig, Andreas ; Wrana, Jeffrey L ; Kislinger, Thomas ; Khokha, Rama

Nature cell biology, 2014-09, Vol.16 (9), p.889-901 [Periódico revisado por pares]

England: Nature Publishing Group

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4
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
Material Type:
Artigo
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BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

Gorrini, Chiara ; Baniasadi, Pegah S ; Harris, Isaac S ; Silvester, Jennifer ; Inoue, Satoshi ; Snow, Bryan ; Joshi, Purna A ; Wakeham, Andrew ; Molyneux, Sam D ; Martin, Bernard ; Bouwman, Peter ; Cescon, David W ; Elia, Andrew J ; Winterton-Perks, Zoe ; Cruickshank, Jennifer ; Brenner, Dirk ; Tseng, Alan ; Musgrave, Melinda ; Berman, Hal K ; Khokha, Rama ; Jonkers, Jos ; Mak, Tak W ; Gauthier, Mona L

The Journal of experimental medicine, 2013-07, Vol.210 (8), p.1529-1544 [Periódico revisado por pares]

United States: The Rockefeller University Press

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5
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
Material Type:
Artigo
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A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

Moriarity, Branden S ; Otto, George M ; Rahrmann, Eric P ; Rathe, Susan K ; Wolf, Natalie K ; Weg, Madison T ; Manlove, Luke A ; LaRue, Rebecca S ; Temiz, Nuri A ; Molyneux, Sam D ; Choi, Kwangmin ; Holly, Kevin J ; Sarver, Aaron L ; Scott, Milcah C ; Forster, Colleen L ; Modiano, Jaime F ; Khanna, Chand ; Hewitt, Stephen M ; Khokha, Rama ; Yang, Yi ; Gorlick, Richard ; Dyer, Michael A ; Largaespada, David A

Nature genetics, 2015-06, Vol.47 (6), p.615-624 [Periódico revisado por pares]

United States: Nature Publishing Group

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6
RANKL blockade prevents and treats aggressive osteosarcomas
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Artigo
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RANKL blockade prevents and treats aggressive osteosarcomas

Chen, Yan ; Di Grappa, Marco A ; Molyneux, Sam D ; McKee, Trevor D ; Waterhouse, Paul ; Penninger, Josef M ; Khokha, Rama

Science translational medicine, 2015-12, Vol.7 (317), p.317ra197-317ra197 [Periódico revisado por pares]

United States

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7
Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas
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Artigo
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Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas

Molyneux, Sam D ; Waterhouse, Paul D ; Shelton, Dawne ; Shao, Yang W ; Watling, Christopher M ; Tang, Qing-Lian ; Harris, Isaac S ; Dickson, Brendan C ; Tharmapalan, Pirashaanthy ; Sandve, Geir K ; Zhang, Xiaoyang ; Bailey, Swneke D ; Berman, Hal ; Wunder, Jay S ; Izsvák, Zsuzsanna ; Lupien, Mathieu ; Mak, Tak W ; Khokha, Rama

Nature genetics, 2020-04, Vol.52 (4), p.464-464 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
Material Type:
Artigo
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Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice

Molyneux, Sam D ; Di Grappa, Marco A ; Beristain, Alexander G ; McKee, Trevor D ; Wai, Daniel H ; Paderova, Jana ; Kashyap, Meenakshi ; Hu, Pingzhao ; Maiuri, Tamara ; Narala, Swami R ; Stambolic, Vuk ; Squire, Jeremy ; Penninger, Josef ; Sanchez, Otto ; Triche, Timothy J ; Wood, Geoffrey A ; Kirschner, Lawrence S ; Khokha, Rama

The Journal of clinical investigation, 2010-09, Vol.120 (9), p.3310-3325 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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9
Human somatic cell mutagenesis creates genetically tractable sarcomas
Material Type:
Artigo
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Human somatic cell mutagenesis creates genetically tractable sarcomas

Molyneux, Sam D ; Waterhouse, Paul D ; Shelton, Dawne ; Shao, Yang W ; Watling, Christopher M ; Tang, Qing-Lian ; Harris, Isaac S ; Dickson, Brendan C ; Tharmapalan, Pirashaanthy ; Sandve, Geir K ; Zhang, Xiaoyang ; Bailey, Swneke D ; Berman, Hal ; Wunder, Jay S ; Izsvák, Zsuzsanna ; Iszvak, Zsuzsanna ; Lupien, Mathieu ; Mak, Tak W ; Khokha, Rama

Nature genetics, 2014-09, Vol.46 (9), p.964-972 [Periódico revisado por pares]

United States: Nature Publishing Group

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10
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Material Type:
Artigo
Adicionar ao Meu Espaço

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Harris, Isaac S. ; Treloar, Aislinn E. ; Inoue, Satoshi ; Sasaki, Masato ; Gorrini, Chiara ; Lee, Kim Chung ; Yung, Ka Yi ; Brenner, Dirk ; Knobbe-Thomsen, Christiane B. ; Cox, Maureen A. ; Elia, Andrew ; Berger, Thorsten ; Cescon, David W. ; Adeoye, Adewunmi ; Brüstle, Anne ; Molyneux, Sam D. ; Mason, Jacqueline M. ; Li, Wanda Y. ; Yamamoto, Kazuo ; Wakeham, Andrew ; Berman, Hal K. ; Khokha, Rama ; Done, Susan J. ; Kavanagh, Terrance J. ; Lam, Ching-Wan ; Mak, Tak W.

Cancer cell, 2015-02, Vol.27 (2), p.314-314 [Periódico revisado por pares]

Elsevier Inc

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