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Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination Therapy
Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination Therapy
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Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination Therapy

Yarur, Andres J ; Kubiliun, Maddie J ; Czul, Frank ; Sussman, Daniel A ; Quintero, Maria A ; Jain, Anjali ; Drake, Katherine A ; Hauenstein, Scott I ; Lockton, Steven ; Deshpande, Amar R ; Barkin, Jamie S ; Singh, Sharat ; Abreu, Maria T

Clinical gastroenterology and hepatology, 2015-06, Vol.13 (6), p.1118-1124.e3 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo
Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo
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Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo

Ma, Yuan ; Zhao, Wenting ; Li, Yiding ; Pan, Yufei ; Wang, Shuhe ; Zhu, Yuejie ; Kong, Lingxuan ; Guan, Zhu ; Wang, Jiancheng ; Zhang, Lihe ; Yang, Zhenjun

Biomaterials, 2019-03, Vol.197, p.182-193 [Periódico revisado por pares]

Netherlands: Elsevier Ltd

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3
Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies
Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies
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Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic Bodies

Wang, Yulian ; Pang, Jiayun ; Wang, Qingyun ; Yan, Luocheng ; Wang, Lintao ; Xing, Zhen ; Wang, Chunming ; Zhang, Junfeng ; Dong, Lei

Advanced science, 2021-07, Vol.8 (13), p.2004929-n/a [Periódico revisado por pares]

Germany: John Wiley & Sons, Inc

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4
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects
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A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects

Edwards, Alena Y. ; Elgart, Anna ; Farrell, Colm ; Barnett‐Griness, Ofra ; Rabinovich‐Guilatt, Laura ; Spiegelstein, Ofer

British journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1932-1943 [Periódico revisado por pares]

England: John Wiley and Sons Inc

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5
Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia
Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia
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Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia

Yu, Bo ; Mao, Yicheng ; Bai, Li-Yuan ; Herman, Sarah E.M. ; Wang, Xinmei ; Ramanunni, Asha ; Jin, Yan ; Mo, Xiaokui ; Cheney, Carolyn ; Chan, Kenneth K. ; Jarjoura, David ; Marcucci, Guido ; Lee, Robert J. ; Byrd, John C. ; Lee, L. James ; Muthusamy, Natarajan

Blood, 2013-01, Vol.121 (1), p.136-147 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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6
A Phase I Pharmacokinetic and Pharmacodynamic Study of OGX-011, a 2′-Methoxyethyl Antisense Oligonucleotide to Clusterin, in Patients With Localized Prostate Cancer
A Phase I Pharmacokinetic and Pharmacodynamic Study of OGX-011, a 2′-Methoxyethyl Antisense Oligonucleotide to Clusterin, in Patients With Localized Prostate Cancer
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A Phase I Pharmacokinetic and Pharmacodynamic Study of OGX-011, a 2′-Methoxyethyl Antisense Oligonucleotide to Clusterin, in Patients With Localized Prostate Cancer

Chi, Kim N. ; Eisenhauer, Elizabeth ; Fazli, Ladan ; Jones, Edward C. ; Goldenberg, S. Larry ; Powers, Jean ; Tu, Dongsheng ; Gleave, Martin E.

JNCI : Journal of the National Cancer Institute, 2005-09, Vol.97 (17), p.1287-1296 [Periódico revisado por pares]

Cary, NC: Oxford University Press

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7
pH-Dependent 5-Aminosalicylates Releasing Preparations Do Not Affect Thiopurine Metabolism
pH-Dependent 5-Aminosalicylates Releasing Preparations Do Not Affect Thiopurine Metabolism
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pH-Dependent 5-Aminosalicylates Releasing Preparations Do Not Affect Thiopurine Metabolism

Takahashi, Kenichiro ; Bamba, Shigeki ; Morita, Yasuhiro ; Nishida, Atsushi ; Kawahara, Masahiro ; Inatomi, Osamu ; Sugimoto, Mitsushige ; Sasaki, Masaya ; Andoh, Akira

Digestion, 2019-11, Vol.100 (4), p.238-246 [Periódico revisado por pares]

Basel, Switzerland

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8
Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors
Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors
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Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors

PLUMMER, Ruth ; VIDAL, Laura ; REID, Gregory K ; MCLEOD, A. Robert ; BESTERMAN, Jeffrey M ; LEE, Chooi ; JUDSON, Ian ; CALVERT, Hilary ; BODDY, Alan V ; GRIFFIN, Melanie ; LESLEY, Mark ; DE BONO, Johann ; COULTHARD, Sally ; SLUDDEN, Julieann ; SIU, Lillian L ; CHEN, Eric X ; OZA, Amit M

Clinical cancer research, 2009-05, Vol.15 (9), p.3177-3183 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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9
Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
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Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

Geary, R S ; Watanabe, T A ; Truong, L ; Freier, S ; Lesnik, E A ; Sioufi, N B ; Sasmor, H ; Manoharan, M ; Levin, A A

The Journal of pharmacology and experimental therapeutics, 2001-03, Vol.296 (3), p.890-897 [Periódico revisado por pares]

United States

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10
A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid Leukemia
A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid Leukemia
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A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid Leukemia

KLISOVIC, Rebecca B ; STOCK, Wendy ; VAN LAAR, Emily ; CULLEN, Michael ; MACLEOD, A. Robert ; BESTERMAN, Jeffrey M ; REID, Gregory K ; BYRD, John C ; MARCUCCI, Guido ; CATALAND, Spero ; KLISOVIC, Marko I ; SHUJUN LIU ; BLUM, William ; GREEN, Margaret ; ODENIKE, Olatoyosi ; GODLEY, Lucy ; VANDEN BURGT, Jennifer

Clinical cancer research, 2008-04, Vol.14 (8), p.2444-2449 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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