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1 |
Material Type: Artigo
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Concentrations of 6-Thioguanine Nucleotide Correlate With Trough Levels of Infliximab in Patients With Inflammatory Bowel Disease on Combination TherapyYarur, Andres J ; Kubiliun, Maddie J ; Czul, Frank ; Sussman, Daniel A ; Quintero, Maria A ; Jain, Anjali ; Drake, Katherine A ; Hauenstein, Scott I ; Lockton, Steven ; Deshpande, Amar R ; Barkin, Jamie S ; Singh, Sharat ; Abreu, Maria TClinical gastroenterology and hepatology, 2015-06, Vol.13 (6), p.1118-1124.e3 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivoMa, Yuan ; Zhao, Wenting ; Li, Yiding ; Pan, Yufei ; Wang, Shuhe ; Zhu, Yuejie ; Kong, Lingxuan ; Guan, Zhu ; Wang, Jiancheng ; Zhang, Lihe ; Yang, ZhenjunBiomaterials, 2019-03, Vol.197, p.182-193 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Delivering Antisense Oligonucleotides across the Blood‐Brain Barrier by Tumor Cell‐Derived Small Apoptotic BodiesWang, Yulian ; Pang, Jiayun ; Wang, Qingyun ; Yan, Luocheng ; Wang, Lintao ; Xing, Zhen ; Wang, Chunming ; Zhang, Junfeng ; Dong, LeiAdvanced science, 2021-07, Vol.8 (13), p.2004929-n/a [Periódico revisado por pares]Germany: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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A population pharmacokinetic meta‐analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjectsEdwards, Alena Y. ; Elgart, Anna ; Farrell, Colm ; Barnett‐Griness, Ofra ; Rabinovich‐Guilatt, Laura ; Spiegelstein, OferBritish journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1932-1943 [Periódico revisado por pares]England: John Wiley and Sons IncTexto completo disponível |
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Material Type: Artigo
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Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemiaYu, Bo ; Mao, Yicheng ; Bai, Li-Yuan ; Herman, Sarah E.M. ; Wang, Xinmei ; Ramanunni, Asha ; Jin, Yan ; Mo, Xiaokui ; Cheney, Carolyn ; Chan, Kenneth K. ; Jarjoura, David ; Marcucci, Guido ; Lee, Robert J. ; Byrd, John C. ; Lee, L. James ; Muthusamy, NatarajanBlood, 2013-01, Vol.121 (1), p.136-147 [Periódico revisado por pares]Washington, DC: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A Phase I Pharmacokinetic and Pharmacodynamic Study of OGX-011, a 2′-Methoxyethyl Antisense Oligonucleotide to Clusterin, in Patients With Localized Prostate CancerChi, Kim N. ; Eisenhauer, Elizabeth ; Fazli, Ladan ; Jones, Edward C. ; Goldenberg, S. Larry ; Powers, Jean ; Tu, Dongsheng ; Gleave, Martin E.JNCI : Journal of the National Cancer Institute, 2005-09, Vol.97 (17), p.1287-1296 [Periódico revisado por pares]Cary, NC: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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pH-Dependent 5-Aminosalicylates Releasing Preparations Do Not Affect Thiopurine MetabolismTakahashi, Kenichiro ; Bamba, Shigeki ; Morita, Yasuhiro ; Nishida, Atsushi ; Kawahara, Masahiro ; Inatomi, Osamu ; Sugimoto, Mitsushige ; Sasaki, Masaya ; Andoh, AkiraDigestion, 2019-11, Vol.100 (4), p.238-246 [Periódico revisado por pares]Basel, SwitzerlandTexto completo disponível |
8 |
Material Type: Artigo
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Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid TumorsPLUMMER, Ruth ; VIDAL, Laura ; REID, Gregory K ; MCLEOD, A. Robert ; BESTERMAN, Jeffrey M ; LEE, Chooi ; JUDSON, Ian ; CALVERT, Hilary ; BODDY, Alan V ; GRIFFIN, Melanie ; LESLEY, Mark ; DE BONO, Johann ; COULTHARD, Sally ; SLUDDEN, Julieann ; SIU, Lillian L ; CHEN, Eric X ; OZA, Amit MClinical cancer research, 2009-05, Vol.15 (9), p.3177-3183 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
9 |
Material Type: Artigo
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Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in ratsGeary, R S ; Watanabe, T A ; Truong, L ; Freier, S ; Lesnik, E A ; Sioufi, N B ; Sasmor, H ; Manoharan, M ; Levin, A AThe Journal of pharmacology and experimental therapeutics, 2001-03, Vol.296 (3), p.890-897 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid LeukemiaKLISOVIC, Rebecca B ; STOCK, Wendy ; VAN LAAR, Emily ; CULLEN, Michael ; MACLEOD, A. Robert ; BESTERMAN, Jeffrey M ; REID, Gregory K ; BYRD, John C ; MARCUCCI, Guido ; CATALAND, Spero ; KLISOVIC, Marko I ; SHUJUN LIU ; BLUM, William ; GREEN, Margaret ; ODENIKE, Olatoyosi ; GODLEY, Lucy ; VANDEN BURGT, JenniferClinical cancer research, 2008-04, Vol.14 (8), p.2444-2449 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |