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Antisense oligonucleotides: the next frontier for treatment of neurological disorders
Antisense oligonucleotides: the next frontier for treatment of neurological disorders
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Antisense oligonucleotides: the next frontier for treatment of neurological disorders

Rinaldi, Carlo ; Wood, Matthew J A

Nature reviews. Neurology, 2018-01, Vol.14 (1), p.9-21 [Periódico revisado por pares]

England: Nature Publishing Group

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2
FDA-Approved Oligonucleotide Therapies in 2017
FDA-Approved Oligonucleotide Therapies in 2017
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FDA-Approved Oligonucleotide Therapies in 2017

Stein, Cy A. ; Castanotto, Daniela

Molecular therapy, 2017-05, Vol.25 (5), p.1069-1075 [Periódico revisado por pares]

United States: Elsevier Inc

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Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo
Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo
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Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo

Ma, Yuan ; Zhao, Wenting ; Li, Yiding ; Pan, Yufei ; Wang, Shuhe ; Zhu, Yuejie ; Kong, Lingxuan ; Guan, Zhu ; Wang, Jiancheng ; Zhang, Lihe ; Yang, Zhenjun

Biomaterials, 2019-03, Vol.197, p.182-193 [Periódico revisado por pares]

Netherlands: Elsevier Ltd

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4
Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
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Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA

Brem, Reto ; Guven, Melisa ; Karran, Peter

Free radical biology & medicine, 2017-06, Vol.107, p.101-109 [Periódico revisado por pares]

United States: Elsevier Inc

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5
The Effects of 2′-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials
The Effects of 2′-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials
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The Effects of 2′-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials

Crooke, Stanley T. ; Baker, Brenda F. ; Witztum, Joseph L. ; Kwoh, T. Jesse ; Pham, Nguyen C. ; Salgado, Nelson ; McEvoy, Bradley W. ; Cheng, Wei ; Hughes, Steven G. ; Bhanot, Sanjay ; Geary, Richard S.

Nucleic acid therapeutics, 2017-06, Vol.27 (3), p.121-129 [Periódico revisado por pares]

United States: Mary Ann Liebert, Inc

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6
Targeting the B-Cell Lymphoma/Leukemia 2 Family in Cancer
Targeting the B-Cell Lymphoma/Leukemia 2 Family in Cancer
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Targeting the B-Cell Lymphoma/Leukemia 2 Family in Cancer

DAVIDS, Matthew S ; LETAI, Anthony

Journal of clinical oncology, 2012-09, Vol.30 (25), p.3127-3135 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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7
Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
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Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial

Beer, Tomasz M ; Hotte, Sebastien J ; Saad, Fred ; Alekseev, Boris ; Matveev, Vsevolod ; Fléchon, Aude ; Gravis, Gwenaelle ; Joly, Florence ; Chi, Kim N ; Malik, Zafar ; Blumenstein, Brent ; Stewart, Patricia S ; Jacobs, Cindy A ; Fizazi, Karim

The lancet oncology, 2017-11, Vol.18 (11), p.1532-1542 [Periódico revisado por pares]

England: Elsevier Ltd

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8
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
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N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells

Richartz, Nina ; Pietka, Wojciech ; Yadav, Ajay ; Bostad, Monica ; Bhagwat, Sampada ; Naderi, Soheil ; Naderi, Elin Hallan ; Stokke, Trond ; Ruud, Ellen ; Blomhoff, Heidi Kiil

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105509-105509, Article 105509 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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9
Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy
Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy
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Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

KANG, Min H ; REYNOLDS, C. Patrick

Clinical cancer research, 2009-02, Vol.15 (4), p.1126-1132 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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10
Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
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Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

Bogdahn, U ; Hau, P ; Stockhammer, G ; Venkataramana, N.K ; Mahapatra, A.K ; Suri, A ; Balasubramaniam, A ; Nair, S ; Oliushine, V ; Parfenov, V ; Poverennova, I ; Zaaroor, M ; Jachimczak, P ; Ludwig, S ; Schmaus, S ; Heinrichs, H ; Schlingensiepen, K.-H

Neuro-oncology (Charlottesville, Va.), 2011-01, Vol.13 (1), p.132-142 [Periódico revisado por pares]

England: Oxford University Press

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