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1
Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum
Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum
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Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

Fernando A. Batista Soraya Soledad Bosch; Sabine Butzloff; Sergey Lunev; Ingrid B Müller; Alexander S. S Dömling; Matthew R Groves; Carsten Wrenger

Microbiology Open Oxford art. 779, p. 1-14, 2019

Oxford 2019

Localização: ICB - Inst. Ciências Biomédicas    (PC ICB BMP SEP 2019 )(Acessar)

2
Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials
Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials
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Discovery of small-molecule allosteric inhibitors of PfATC as antimalarials

Chao Wang Bidong Zhang; Arne Krüger; Xiaochen Du; Lidia Visser; Alexander S. S Dömling; Carsten Wrenger; Matthew R Groves

Journal of American Chemical Society Washington p. 1-8, 2022

Washington 2022

Item não circula. Consulte sua biblioteca.(Acessar)

3
Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2
Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2
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Molecular target validation of aspartate transcarbamoylase from Plasmodium falciparum by torin 2

Soraya Soledad Bosch Sergey Lunev; Fernando de Assis Batista; Marleen Linzke; Thales Kronenberger; Alexander S. S Dömling; Matthew R Groves; Carsten Wrenger

ACS Infectious Diseases Washington, DC v. 6. n. 5, p. 986-999, 2020

Washington, DC 2020

Item não circula. Consulte sua biblioteca.(Acessar)

4
Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase
Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase
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Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase

Sergey Lunev Soraya S Bosch; Fernando A Batista; Chao Wang; Jingyao Li; Marleen Linzke; Paul Kruithof; George Chamoun; Alexander S.S Domling; Carsten Wrenger; Matthew R Groves

Biochemical and Biophysical Research Communications Philadelphia v. 497,n.3, p.835-842, 2018

Philadelphia 2018

Localização: ICB - Inst. Ciências Biomédicas    (PC ICB BMP SEP 2018 )(Acessar)

5
The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries
The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries
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The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries

Ugi, I. ; Werner, B. ; Dömling, A.

Molecules (Basel, Switzerland), 2003-01, Vol.8 (1), p.53-66 [Periódico revisado por pares]

Basel: MDPI AG

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6
Protein-Protein Interactions in Drug Discovery
Protein-Protein Interactions in Drug Discovery
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Protein-Protein Interactions in Drug Discovery

Douml;mling, Alexander ; Folkers, Gerd ; Kubinyi, Hugo ; Mannhold, Raimund

Newark: Wiley-VCH 2013

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7
Multicomponent Reactions with Isocyanides
Multicomponent Reactions with Isocyanides
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Multicomponent Reactions with Isocyanides

Dömling, Alexander ; Ugi, Ivar

Angewandte Chemie (International ed.), 2000-09, Vol.39 (18), p.3168-3210 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag GmbH

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8
Isocyanide-based Multicomponent Reactions
Isocyanide-based Multicomponent Reactions
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Isocyanide-based Multicomponent Reactions

Dömling, Alexander ; Shaabani, Shabnam ; Rudick, Jonathan G

Frontiers Media SA 2020

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9
Pharmacological screening identifies SHK242 and SHK277 as novel arginase inhibitors with efficacy against allergen-induced airway narrowing in vitro and in vivo
Pharmacological screening identifies SHK242 and SHK277 as novel arginase inhibitors with efficacy against allergen-induced airway narrowing in vitro and in vivo
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Pharmacological screening identifies SHK242 and SHK277 as novel arginase inhibitors with efficacy against allergen-induced airway narrowing in vitro and in vivo

Van den Berg, Mariska P M ; Kurhade, Santosh H ; Maarsingh, Harm ; Erceg, Stefanie ; Hulsbeek, Imke R ; Boekema, Pieter H ; Kistemaker, Loes E M ; van Faassen, Martijn ; Kema, Ido P ; Elsinga, Philip H ; Dömling, Alex S S ; Meurs, Herman ; Gosens, Reinoud

The Journal of pharmacology and experimental therapeutics, 2020-07, Vol.374 (1), p.62-73 [Periódico revisado por pares]

United States

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10
The discovery of new isocyanide-based multi-component reactions
The discovery of new isocyanide-based multi-component reactions
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The discovery of new isocyanide-based multi-component reactions

Doemling, A

Current Opinion in Chemical Biology, 2000-06, Vol.4 (3), p.318-323 [Periódico revisado por pares]

England: Elsevier Ltd

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Deste Autor:

  1. Groves, M
  2. Wrenger, C
  3. Batista, F
  4. Dömling, A
  5. Lunev, S

Neste Assunto:

  1. Science & Technology
  2. Chemistry
  3. Physical Sciences
  4. Life Sciences & Biomedicine
  5. Chemistry, Organic

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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