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1
An exercise-inducible metabolite that suppresses feeding and obesity
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Artigo
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An exercise-inducible metabolite that suppresses feeding and obesity

Li, Veronica L ; He, Yang ; Contrepois, Kévin ; Liu, Hailan ; Kim, Joon T ; Wiggenhorn, Amanda L ; Tanzo, Julia T ; Tung, Alan Sheng-Hwa ; Lyu, Xuchao ; Zushin, Peter-James H ; Jansen, Robert S ; Michael, Basil ; Loh, Kang Yong ; Yang, Andrew C ; Carl, Christian S ; Voldstedlund, Christian T ; Wei, Wei ; Terrell, Stephanie M ; Moeller, Benjamin C ; Arthur, Rick M ; Wallis, Gareth A ; van de Wetering, Koen ; Stahl, Andreas ; Kiens, Bente ; Richter, Erik A ; Banik, Steven M ; Snyder, Michael P ; Xu, Yong ; Long, Jonathan Z

Nature (London), 2022-06, Vol.606 (7915), p.785-790 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
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Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity

Schnaider, Lee ; Brahmachari, Sayanti ; Schmidt, Nathan W ; Mensa, Bruk ; Shaham-Niv, Shira ; Bychenko, Darya ; Adler-Abramovich, Lihi ; Shimon, Linda J W ; Kolusheva, Sofiya ; DeGrado, William F ; Gazit, Ehud

Nature communications, 2017-11, Vol.8 (1), p.1365-10, Article 1365 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities
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Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities

Sun, Lin ; Huang, Tianguang ; Dick, Alexej ; Meuser, Megan E. ; Zalloum, Waleed A. ; Chen, Chin-Ho ; Ding, Xiao ; Gao, Ping ; Cocklin, Simon ; Lee, Kuo-Hsiung ; Zhan, Peng ; Liu, Xinyong

European journal of medicinal chemistry, 2020-03, Vol.190, p.112085-112085, Article 112085 [Periódico revisado por pares]

France: Elsevier Masson SAS

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4
Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase
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Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase

Kozlenkov, Alexey ; Le Du, Marie Helene ; Cuniasse, Philippe ; Ny, Tor ; Hoylaerts, Marc F ; Millán, José Luis

Journal of bone and mineral research, 2004-11, Vol.19 (11), p.1862-1872 [Periódico revisado por pares]

Washington, DC: John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR)

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5
Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities
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Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities

Sun, Lin ; Dick, Alexej ; Meuser, Megan E ; Huang, Tianguang ; Zalloum, Waleed A ; Chen, Chin-Ho ; Cherukupalli, Srinivasulu ; Xu, Shujing ; Ding, Xiao ; Gao, Ping ; Kang, Dongwei ; De Clercq, Erik ; Pannecouque, Christophe ; Cocklin, Simon ; Lee, Kuo-Hsiung ; Liu, Xinyong ; Zhan, Peng

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4790-4810 [Periódico revisado por pares]

United States: American Chemical Society

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6
Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug
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Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug

Costa, Simone A ; Mozhdehi, Davoud ; Dzuricky, Michael J ; Isaacs, Farren J ; Brustad, Eric M ; Chilkoti, Ashutosh

Nano letters, 2019-01, Vol.19 (1), p.247-254 [Periódico revisado por pares]

United States: American Chemical Society

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7
Off-Pathway Assembly: A Broad-Spectrum Mechanism of Action for Drugs That Undermine Controlled HIV‑1 Viral Capsid Formation
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Off-Pathway Assembly: A Broad-Spectrum Mechanism of Action for Drugs That Undermine Controlled HIV‑1 Viral Capsid Formation

Pak, Alexander J ; Grime, John M. A ; Yu, Alvin ; Voth, Gregory A

Journal of the American Chemical Society, 2019-07, Vol.141 (26), p.10214-10224 [Periódico revisado por pares]

United States: American Chemical Society

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8
Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library
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Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library

Wu, Gaochan ; Zalloum, Waleed A. ; Meuser, Megan E. ; Jing, Lanlan ; Kang, Dongwei ; Chen, Chin-Ho ; Tian, Ye ; Zhang, Fangfang ; Cocklin, Simon ; Lee, Kuo-Hsiung ; Liu, Xinyong ; Zhan, Peng

European journal of medicinal chemistry, 2018-10, Vol.158, p.478-492 [Periódico revisado por pares]

France: Elsevier Masson SAS

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9
Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B
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Artigo
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Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B

Hogarth, Marshall W ; Defour, Aurelia ; Lazarski, Christopher ; Gallardo, Eduard ; Diaz Manera, Jordi ; Partridge, Terence A ; Nagaraju, Kanneboyina ; Jaiswal, Jyoti K

Nature communications, 2019-06, Vol.10 (1), p.2430-13, Article 2430 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain‑2 for the Treatment of Neglected Tropical Diseases (NTDs)
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Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain‑2 for the Treatment of Neglected Tropical Diseases (NTDs)

Previti, Santo ; Ettari, Roberta ; Cosconati, Sandro ; Amendola, Giorgio ; Chouchene, Khawla ; Wagner, Annika ; Hellmich, Ute A ; Ulrich, Kathrin ; Krauth-Siegel, R. Luise ; Wich, Peter R ; Schmid, Ira ; Schirmeister, Tanja ; Gut, Jiri ; Rosenthal, Philip J ; Grasso, Silvana ; Zappalà, Maria

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.6911-6923 [Periódico revisado por pares]

United States: American Chemical Society

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