Genomic landscape of platinum resistant and sensitive testicular cancers

Loveday, Chey ; Litchfield, Kevin ; Proszek, Paula Z ; Cornish, Alex J ; Santo, Flavia ; Levy, Max ; Macintyre, Geoff ; Holryod, Amy ; Broderick, Peter ; Dudakia, Darshna ; Benton, Barbara ; Bakir, Maise Al ; Hiley, Crispin ; Grist, Emily ; Swanton, Charles ; Huddart, Robert ; Powles, Tom ; Chowdhury, Simon ; Shipley, Janet ; O'Connor, Simon ; Brenton, James D ; Reid, Alison ; de Castro, David Gonzalez ; Houlston, Richard S ; Turnbull, Clare

England: Nature Publishing Group

Texto completo disponível

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

Litchfield, Kevin ; Reading, James L ; Lim, Emilia L ; Xu, Hang ; Liu, Po ; Al-Bakir, Maise ; Wong, Yien Ning Sophia ; Rowan, Andrew ; Funt, Samuel A ; Merghoub, Taha ; Perkins, David ; Lauss, Martin ; Svane, Inge Marie ; Jönsson, Göran ; Herrero, Javier ; Larkin, James ; Quezada, Sergio A ; Hellmann, Matthew D ; Turajlic, Samra ; Swanton, Charles

England: Nature Publishing Group

Texto completo disponível

Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis

Turajlic, Samra ; Litchfield, Kevin ; Xu, Hang ; Rosenthal, Rachel ; McGranahan, Nicholas ; Reading, James L ; Wong, Yien Ning S ; Rowan, Andrew ; Kanu, Nnennaya ; Al Bakir, Maise ; Chambers, Tim ; Salgado, Roberto ; Savas, Peter ; Loi, Sherene ; Birkbak, Nicolai J ; Sansregret, Laurent ; Gore, Martin ; Larkin, James ; Quezada, Sergio A ; Swanton, Charles

England: Elsevier Ltd

Texto completo disponível

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

Litchfield, Kevin ; Reading, James L. ; Puttick, Clare ; Thakkar, Krupa ; Abbosh, Chris ; Bentham, Robert ; Watkins, Thomas B.K. ; Rosenthal, Rachel ; Biswas, Dhruva ; Rowan, Andrew ; Lim, Emilia ; Al Bakir, Maise ; Turati, Virginia ; Guerra-Assunção, José Afonso ; Conde, Lucia ; Furness, Andrew J.S. ; Saini, Sunil Kumar ; Hadrup, Sine R. ; Herrero, Javier ; Lee, Se-Hoon ; Van Loo, Peter ; Enver, Tariq ; Larkin, James ; Hellmann, Matthew D. ; Turajlic, Samra ; Quezada, Sergio A. ; McGranahan, Nicholas ; Swanton, Charles

United States: Elsevier Inc

Texto completo disponível

Neoantigen-directed immune escape in lung cancer evolution

Rosenthal, Rachel ; Cadieux, Elizabeth Larose ; Salgado, Roberto ; Bakir, Maise Al ; Moore, David A ; Hiley, Crispin T ; Lund, Tom ; Tanić, Miljana ; Reading, James L ; Joshi, Kroopa ; Henry, Jake Y ; Ghorani, Ehsan ; Wilson, Gareth A ; Birkbak, Nicolai J ; Jamal-Hanjani, Mariam ; Veeriah, Selvaraju ; Szallasi, Zoltan ; Loi, Sherene ; Hellmann, Matthew D ; Feber, Andrew ; Chain, Benny ; Herrero, Javier ; Quezada, Sergio A ; Demeulemeester, Jonas ; Van Loo, Peter ; Beck, Stephan ; McGranahan, Nicholas ; Swanton, Charles

England: Nature Publishing Group

Texto completo disponível

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Furness, Andrew J.S. ; Joshi, Kroopa ; Rosenthal, Rachel ; Ghorani, Ehsan ; Spain, Lavinia ; Ben Aissa, Assma ; Smith, Myles ; Strauss, Dirk ; Hayes, Andrew ; Nicol, David ; Mårtensson, Linda ; Harrington, Kevin ; Wotherspoon, Andrew ; Fernando, Archana ; Chandra, Ashish ; Rudman, Sarah ; Varia, Mary ; Polson, Alexander ; Stamp, Gordon ; Hill, Peter ; Olsburgh, Jonathan ; Lester, Jason ; Attanoos, Richard ; Adams, Haydn ; Shaw, Jacqui ; Le Quesne, John ; Marshall, Hilary ; Nelson, Louise ; Bennett, Jonathan ; Martinson, Luke ; Kerr, Keith ; Miller, Joy ; Naidu, Babu ; Langman, Gerald ; Bellamy, Mary ; Summers, Yvonne ; Shah, Rajesh ; Rammohan, Kendadai ; Booton, Richard ; Moss, Stuart ; Idries, Faiza ; Joseph, Leena ; Chaturvedi, Anshuman ; Marie Quinn, Anne ; Doran, Helen ; Waddington, Rachael ; Blackhall, Fiona ; Rogan, Jane ; Smith, Elaine ; Dive, Caroline ; Brady, Ged ; Chemie, Francesca ; Tugwood, Jonathan ; Lawrence, David ; Panagiotopoulos, Nikolaos ; Falzon, Mary ; Borg, Elaine ; Jamal-Hanjani, Mariam ; Juul Birkbak, Nicolai ; McGranahan, Nicholas ; Goldman, Jacki ; Veeriah, Raju ; Johnson, Diana ; Oukrif, Dahmane ; Janes, Sam ; Hartley, John ; Kevin Stone, Richard ; Denner, Tamara ; Costa, Marta ; Phillimore, Ben ; Nye, Emma ; Elgar, Greg ; Al-Bakir, Maise ; Navani, Neal ; Gorman, Pat ; MacKenzie, Mairead ; Bell, Harriet ; Hackshaw, Allan ; Smith, Sean ; Shaw, Emily ; Lim, Eric ; Nicholson, Andrew ; Rice, Alexandra ; Carlo Ronquillo, John ; Mensah, Natalie ; Finch, Jonathan ; Lau, Kelvin ; Schmid, Peter ; Conibear, John ; Danson, Sarah ; Bury, Jonathan ; Hill, Jennifer ; Shackcloth, Michael ; Feeney, Sarah ; Asante-Siaw, Julius ; Blyth, Kevin ; Kirk, Alan ; Pule, Martin ; Turajlic, Samra ; Peggs, Karl S.

United States: Elsevier Inc

Texto completo disponível

Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

López, Saioa ; Lim, Emilia L ; Horswell, Stuart ; Haase, Kerstin ; Huebner, Ariana ; Dietzen, Michelle ; Mourikis, Thanos P ; Watkins, Thomas B K ; Rowan, Andrew ; Dewhurst, Sally M ; Birkbak, Nicolai J ; Wilson, Gareth A ; Van Loo, Peter ; Jamal-Hanjani, Mariam ; Swanton, Charles ; McGranahan, Nicholas

United States: Nature Publishing Group

Texto completo disponível

Abstract PO-018: Single cell whole genome sequencing reveals the dynamics of copy number instability at the earliest stages of cancer evolution

Frankell, Alexander M. ; Hobor, Sebastian ; Al-bakir, Maise ; Grönroos, Eva ; Swanton, Charles

Texto completo disponível

Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts

Bortolomeazzi, Michele ; Keddar, Mohamed Reda ; Montorsi, Lucia ; Acha-Sagredo, Amelia ; Benedetti, Lorena ; Temelkovski, Damjan ; Choi, Subin ; Petrov, Nedyalko ; Todd, Katrina ; Wai, Patty ; Kohl, Johannes ; Denner, Tamara ; Nye, Emma ; Goldstone, Robert ; Ward, Sophia ; Wilson, Gareth A. ; Al Bakir, Maise ; Swanton, Charles ; John, Susan ; Miles, James ; Larijani, Banafshe ; Kunene, Victoria ; Fontana, Elisa ; Arkenau, Hendrik-Tobias ; Parker, Peter J. ; Rodriguez-Justo, Manuel ; Shiu, Kai-Keen ; Spencer, Jo ; Ciccarelli, Francesca D.

United States: Elsevier Inc

Texto completo disponível

Cancer biomarkers: Emerging trends and clinical implications for personalized treatment

Passaro, Antonio ; Al Bakir, Maise ; Hamilton, Emily G. ; Diehn, Maximilian ; André, Fabrice ; Roy-Chowdhuri, Sinchita ; Mountzios, Giannis ; Wistuba, Ignacio I. ; Swanton, Charles ; Peters, Solange

United States: Elsevier Inc

Texto completo disponível