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1
Synthesis and structure–activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32
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Artigo
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Synthesis and structure–activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32

Kawate, Tomohiko ; Iwase, Noriaki ; Shimizu, Motohisa ; Stanley, Sarah A. ; Wellington, Samantha ; Kazyanskaya, Edward ; Hung, Deborah T.

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (22), p.6052-6059 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Antibiotic adjuvants – A strategy to unlock bacterial resistance to antibiotics
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Artigo
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Antibiotic adjuvants – A strategy to unlock bacterial resistance to antibiotics

González-Bello, Concepción

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4221-4228 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands
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Artigo
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Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands

Iio, Keita ; Kutsumura, Noriki ; Nagumo, Yasuyuki ; Saitoh, Tsuyoshi ; Tokuda, Akihisa ; Hashimoto, Kao ; Yamamoto, Naoshi ; Kise, Ryoji ; Inoue, Asuka ; Mizoguchi, Hirokazu ; Nagase, Hiroshi

Bioorganic & medicinal chemistry letters, 2022-01, Vol.56, p.128485-128485, Article 128485 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma
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Artigo
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Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma

Sturdivant, Jill M. ; Royalty, Susan M. ; Lin, Cheng-Wen ; Moore, Lori A. ; Yingling, Jeffrey D. ; Laethem, Carmen L. ; Sherman, Bryan ; Heintzelman, Geoffrey R. ; Kopczynski, Casey C. ; deLong, Mitchell A.

Bioorganic & medicinal chemistry letters, 2016-05, Vol.26 (10), p.2475-2480 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Structure guided design of a series of sphingosine kinase (SphK) inhibitors
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Artigo
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Structure guided design of a series of sphingosine kinase (SphK) inhibitors

Gustin, Darin J. ; Li, Yihong ; Brown, Matthew L. ; Min, Xiaoshan ; Schmitt, Mike J. ; Wanska, Malgorzata ; Wang, Xiaodong ; Connors, Richard ; Johnstone, Sheere ; Cardozo, Mario ; Cheng, Alan C. ; Jeffries, Shawn ; Franks, Brendon ; Li, Shyun ; Shen, Shanling ; Wong, Mariwil ; Wesche, Holger ; Xu, Guifen ; Carlson, Timothy J. ; Plant, Matthew ; Morgenstern, Kurt ; Rex, Karen ; Schmitt, Joanna ; Coxon, Angela ; Walker, Nigel ; Kayser, Frank ; Wang, Zhulun

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4608-4616 [Periódico revisado por pares]

England: Elsevier Ltd

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6
Rynaxypyr™: A new insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activator
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Artigo
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Rynaxypyr™: A new insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activator

Lahm, George P. ; Stevenson, Thomas M. ; Selby, Thomas P. ; Freudenberger, John H. ; Cordova, Daniel ; Flexner, Lindsey ; Bellin, Cheryl A. ; Dubas, Christine M. ; Smith, Ben K. ; Hughes, Kenneth A. ; Hollingshaus, J. Gary ; Clark, Christopher E. ; Benner, Eric A.

Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6274-6279 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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7
Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core
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Artigo
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Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Sivaprakasam, Prasanna ; Han, Xiaojun ; Civiello, Rita L ; Jacutin-Porte, Swanee ; Kish, Kevin ; Pokross, Matt ; Lewis, Hal A ; Ahmed, Nazia ; Szapiel, Nicolas ; Newitt, John A ; Baldwin, Eric T ; Xiao, Hong ; Krause, Carol M ; Park, Hyunsoo ; Nophsker, Michelle ; Lippy, Jonathan S ; Burton, Catherine R ; Langley, David R ; Macor, John E ; Dubowchik, Gene M

Bioorganic & medicinal chemistry letters, 2015-05, Vol.25 (9), p.1856-1863 [Periódico revisado por pares]

England

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8
The use of spirocyclic scaffolds in drug discovery
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Artigo
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The use of spirocyclic scaffolds in drug discovery

Zheng, Yajun ; Tice, Colin M. ; Singh, Suresh B.

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (16), p.3673-3682 [Periódico revisado por pares]

England: Elsevier Ltd

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9
Design, synthesis, evaluation, and molecular docking of ursolic acid derivatives containing a nitrogen heterocycle as anti-inflammatory agents
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Artigo
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Design, synthesis, evaluation, and molecular docking of ursolic acid derivatives containing a nitrogen heterocycle as anti-inflammatory agents

Wei, Zhi-Yu ; Chi, Ke-Qiang ; Wang, Ke-Si ; Wu, Jie ; Liu, Li-Ping ; Piao, Hu-Ri

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1797-1803 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Inhibition of kynurenine production by N,O-substituted hydroxylamine derivatives
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Artigo
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Inhibition of kynurenine production by N,O-substituted hydroxylamine derivatives

Iijima, Masatomi ; Otsuka, Yasunari ; Ohba, Shun-ichi ; Momose, Isao

Bioorganic & medicinal chemistry letters, 2024-07, Vol.106, p.129731-129731, Article 129731 [Periódico revisado por pares]

England: Elsevier Ltd

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