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Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain
Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain
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Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain

Tsuno, Naoki ; Yukimasa, Akira ; Yoshida, Osamu ; Suzuki, Shinji ; Nakai, Hiromi ; Ogawa, Tomoyuki ; Fujiu, Motohiro ; Takaya, Kenji ; Nozu, Azusa ; Yamaguchi, Hiroki ; Matsuda, Hidetoshi ; Funaki, Satoko ; Yamanada, Natsue ; Tanimura, Miki ; Nagamatsu, Daiki ; Asaki, Toshiyuki ; Horita, Narumi ; Yamamoto, Miyuki ; Hinata, Mikie ; Soga, Masahiko ; Imai, Masayuki ; Morioka, Yasuhide ; Kanemasa, Toshiyuki ; Sakaguchi, Gaku ; Iso, Yasuyoshi

Bioorganic & medicinal chemistry, 2017-04, Vol.25 (7), p.2177-2190 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Rational Design, Synthesis, and Characterization of Novel Inhibitors for Human β1,4-Galactosyltransferase
Rational Design, Synthesis, and Characterization of Novel Inhibitors for Human β1,4-Galactosyltransferase
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Rational Design, Synthesis, and Characterization of Novel Inhibitors for Human β1,4-Galactosyltransferase

Takaya, Kenji ; Nagahori, Noriko ; Kurogochi, Masaki ; Furuike, Tetsuya ; Miura, Nobuaki ; Monde, Kenji ; Lee, Yuan Chuan ; Nishimura, Shin-Ichiro

Journal of medicinal chemistry, 2005-09, Vol.48 (19), p.6054-6065 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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3
Identification and expression-profiling of Xenopus tropicalis miRNAs including plant miRNA-like RNAs at metamorphosis
Identification and expression-profiling of Xenopus tropicalis miRNAs including plant miRNA-like RNAs at metamorphosis
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Identification and expression-profiling of Xenopus tropicalis miRNAs including plant miRNA-like RNAs at metamorphosis

Hikosaka, Akira ; Takaya, Kenji ; Jinno, Michiko ; Kawahara, Akira

FEBS letters, 2007-06, Vol.581 (16), p.3013-3018 [Periódico revisado por pares]

England: Elsevier B.V

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4
Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease
Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease
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Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease

Miyagawa, Masayoshi ; Akiyama, Toshiyuki ; Taoda, Yoshiyuki ; Takaya, Kenji ; Takahashi-Kageyama, Chika ; Tomita, Kenji ; Yasuo, Kazuya ; Hattori, Kazunari ; Shano, Shinya ; Yoshida, Ryu ; Shishido, Takao ; Yoshinaga, Tomokazu ; Sato, Akihiko ; Kawai, Makoto

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.8101-8114 [Periódico revisado por pares]

United States: American Chemical Society

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5
Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction
Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction
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Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction

Juncosa, Jose I ; Takaya, Kenji ; Le, Hoang V ; Moschitto, Matthew J ; Weerawarna, Pathum M ; Mascarenhas, Romila ; Liu, Dali ; Dewey, Stephen L ; Silverman, Richard B

Journal of the American Chemical Society, 2018-02, Vol.140 (6), p.2151-2164 [Periódico revisado por pares]

United States: American Chemical Society

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6
Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease
Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease
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Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease

Miyagawa, Masayoshi ; Akiyama, Toshiyuki ; Mikamiyama-Iwata, Minako ; Hattori, Kazunari ; Kurihara, Naoko ; Taoda, Yoshiyuki ; Takahashi-Kageyama, Chika ; Kurose, Noriyuki ; Mikamiyama, Hidenori ; Suzuki, Naoyuki ; Takaya, Kenji ; Tomita, Kenji ; Matsuo, Kenji ; Morimoto, Kenji ; Yoshida, Ryu ; Shishido, Takao ; Yoshinaga, Tomokazu ; Sato, Akihiko ; Kawai, Makoto

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4739-4742 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent GABA Aminotransferase Inactivator for the Treatment of Addiction
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent GABA Aminotransferase Inactivator for the Treatment of Addiction
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Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent GABA Aminotransferase Inactivator for the Treatment of Addiction

Juncosa, Jose I. ; Takaya, Kenji ; Le, Hoang V. ; Moschitto, Matthew J. ; Weerawarna, Pathum M. ; Mascarenhas, Romila ; Liu, Dali ; Dewey, Stephen L. ; Silverman, Richard B.

Journal of the American Chemical Society, 2018-01, Vol.140 (6), p.2151-2164 [Periódico revisado por pares]

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8
Discovery of novel 2′,4′-dimethyl-[4,5′-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 2
Discovery of novel 2′,4′-dimethyl-[4,5′-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 2
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Discovery of novel 2′,4′-dimethyl-[4,5′-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 2

Tsuno, Naoki ; Yukimasa, Akira ; Yoshida, Osamu ; Suzuki, Shinji ; Nakai, Hiromi ; Ogawa, Tomoyuki ; Fujiu, Motohiro ; Takaya, Kenji ; Nozu, Azusa ; Yamaguchi, Hiroki ; Matsuda, Hidetoshi ; Funaki, Satoko ; Nishimura, Yoko ; Ito, Tetsuji ; Nagamatsu, Daiki ; Asaki, Toshiyuki ; Horita, Narumi ; Yamamoto, Miyuki ; Hinata, Mikie ; Soga, Masahiko ; Imai, Masayuki ; Morioka, Yasuhide ; Kanemasa, Toshiyuki ; Sakaguchi, Gaku ; Iso, Yasuyoshi

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4936-4941 [Periódico revisado por pares]

England: Elsevier Ltd

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9
Direct Observation of Sugar-Protein, Sugar-Sugar, and Sugar-Water Complexes by Cold-Spray Ionization Time-of-Flight Mass Spectrometry
Direct Observation of Sugar-Protein, Sugar-Sugar, and Sugar-Water Complexes by Cold-Spray Ionization Time-of-Flight Mass Spectrometry
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Direct Observation of Sugar-Protein, Sugar-Sugar, and Sugar-Water Complexes by Cold-Spray Ionization Time-of-Flight Mass Spectrometry

Nishimura, Shin-Ichiro ; Nagahori, Noriko ; Takaya, Kenji ; Tachibana, Yuki ; Miura, Nobuaki ; Monde, Kenji

Angewandte Chemie (International ed.), 2005-01, Vol.44 (4), p.571-575 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

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10
The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif
The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif
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The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif

Fujitani, Naoki ; Kouno, Takahide ; Nakahara, Taku ; Takaya, Kenji ; Osaki, Tsukasa ; Kawabata, Shun-ichiro ; Mizuguchi, Mineyuki ; Aizawa, Tomoyasu ; Demura, Makoto ; Nishimura, Shin-Ichiro ; Kawano, Keiichi

Journal of peptide science, 2007-04, Vol.13 (4), p.269-279 [Periódico revisado por pares]

Chichester, UK: John Wiley & Sons, Ltd

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