Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
---|---|---|---|
1 |
Material Type: Artigo
|
![]() |
Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinaseBago, Ruzica ; Malik, Nazma ; Munson, Michael J ; Prescott, Alan R ; Davies, Paul ; Sommer, Eeva ; Shpiro, Natalia ; Ward, Richard ; Cross, Darren ; Ganley, Ian G ; Alessi, Dario RBiochemical journal, 2014-11, Vol.463 (3), p.413-427 [Periódico revisado por pares]England: Portland Press LtdTexto completo disponível |
2 |
Material Type: Artigo
|
![]() |
Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinomaJin, Nan ; Keam, Bhumsuk ; Cho, Janice ; Lee, Michelle J ; Kim, Hye Ryun ; Torosyan, Hayarpi ; Jura, Natalia ; Ng, Patrick Ks ; Mills, Gordon B ; Li, Hua ; Zeng, Yan ; Barbash, Zohar ; Tarcic, Gabi ; Kang, Hyunseok ; Bauman, Julie E ; Kim, Mi-Ok ; VanLandingham, Nathan K ; Swaney, Danielle L ; Krogan, Nevan J ; Johnson, Daniel E ; Grandis, Jennifer RThe Journal of clinical investigation, 2021-11, Vol.131 (22), p.1-15 [Periódico revisado por pares]United States: American Society for Clinical InvestigationTexto completo disponível |
3 |
Material Type: Artigo
|
![]() |
Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissueAraiz, Caroline ; Yan, Anqi ; Bettedi, Lucia ; Samuelson, Isabella ; Virtue, Sam ; McGavigan, Anne K ; Dani, Christian ; Vidal-Puig, Antonio ; Foukas, Lazaros CNature communications, 2019-04, Vol.10 (1), p.1546-14, Article 1546 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
4 |
Material Type: Artigo
|
![]() |
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitorsVasan, Neil ; Razavi, Pedram ; Johnson, Jared L ; Shao, Hong ; Shah, Hardik ; Antoine, Alesia ; Ladewig, Erik ; Gorelick, Alexander ; Lin, Ting-Yu ; Toska, Eneda ; Xu, Guotai ; Kazmi, Abiha ; Chang, Matthew T ; Taylor, Barry S ; Dickler, Maura N ; Jhaveri, Komal ; Chandarlapaty, Sarat ; Rabadan, Raul ; Reznik, Ed ; Smith, Melissa L ; Sebra, Robert ; Schimmoller, Frauke ; Wilson, Timothy R ; Friedman, Lori S ; Cantley, Lewis C ; Scaltriti, Maurizio ; Baselga, JoséScience (American Association for the Advancement of Science), 2019-11, Vol.366 (6466), p.714-723 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
5 |
Material Type: Artigo
|
![]() |
PIK3CA variants selectively initiate brain hyperactivity during gliomagenesisYu, Kwanha ; Lin, Chia-Ching John ; Hatcher, Asante ; Lozzi, Brittney ; Kong, Kathleen ; Huang-Hobbs, Emmet ; Cheng, Yi-Ting ; Beechar, Vivek B ; Zhu, Wenyi ; Zhang, Yiqun ; Chen, Fengju ; Mills, Gordon B ; Mohila, Carrie A ; Creighton, Chad J ; Noebels, Jeffrey L ; Scott, Kenneth L ; Deneen, BenjaminNature (London), 2020-02, Vol.578 (7793), p.166-171 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
6 |
Material Type: Artigo
|
![]() |
Targeting the PI3-kinase pathway in triple-negative breast cancerPascual, J. ; Turner, N.C.Annals of oncology, 2019-07, Vol.30 (7), p.1051-1060 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
7 |
Material Type: Artigo
|
![]() |
Herpesviruses in the Activated Phosphatidylinositol-3-Kinase-δ SyndromeCohen, Jeffrey IFrontiers in immunology, 2018-02, Vol.9, p.237-237 [Periódico revisado por pares]Switzerland: Frontiers Media S.ATexto completo disponível |
8 |
Material Type: Artigo
|
![]() |
PIK3CA in cancer: The past 30 yearsArafeh, Rand ; Samuels, YardenaSeminars in cancer biology, 2019-12, Vol.59, p.36-49 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
9 |
Material Type: Artigo
|
![]() |
Inhibition of Human Class I vs Class III Phosphatidylinositol 3′-KinasesHassett, Matthew R ; Sternberg, Anna R ; Roepe, Paul DBiochemistry (Easton), 2017-08, Vol.56 (33), p.4326-4334 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
10 |
Material Type: Artigo
|
![]() |
Discovery of a Potent and Selective PI3Kδ Inhibitor ( S )-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4 H -quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer ModelsShukla, Manojkumar R ; Patra, Sukanya ; Verma, Mahip ; Sadasivam, Gayathri ; Jana, Nirmal ; Mahangare, Sachin J ; Vidhate, Prashant ; Lagad, Dipak ; Tarage, Anand ; Cheemala, Murthy ; Kulkarni, Chaitanya ; Bhagwat, Shankar ; Chaudhari, Vinod D ; Sayyed, Majid ; Pachpute, Vipul ; Phadtare, Ramesh ; Gole, Gopal ; Phukan, Samiron ; Sunkara, Brahmam ; Samant, Charudatt ; Shingare, Manisha ; Naik, Aditya ; Trivedi, Sneha ; Marisetti, Ajit Kumar ; Reddy, Madhusudhan ; Gholve, Milind ; Mahajan, Nilesh ; Sabde, Sudeep ; Patil, Vinod ; Modi, Dipak ; Mehta, Maneesh ; Nigade, Prashant ; Tamane, Kaustubh ; Tota, Swati ; Goyal, Hemant ; Volam, Harish ; Pawar, Shashikant ; Ahirrao, Prajakta ; Dinchhana, Lal ; Mallurwar, Sadanand ; Akarte, Atul ; Bokare, Anand ; Kanhere, Rupesh ; Reddy, Neetinkumar ; Koul, Sarita ; Dandekar, Manoj ; Singh, Minakshi ; Bernstein, Peter R ; Narasimham, Lakshmi ; Bhonde, Mandar ; Gundu, Jayasagar ; Goel, Rajan ; Kulkarni, Sanjeev ; Sharma, Sharad ; Kamboj, Rajender Kumar ; Palle, Venkata PJournal of medicinal chemistry, 2020-12, Vol.63 (23), p.14700-14723 [Periódico revisado por pares]United StatesTexto completo disponível |