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Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
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Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide

Varma, Manthena V S ; Lin, Jian ; Bi, Yi-an ; Kimoto, Emi ; Rodrigues, A David

Drug metabolism and disposition, 2015-07, Vol.43 (7), p.1108-1118 [Periódico revisado por pares]

United States

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2
Mass changes in remnant cholesterol and LDL cholesterol explain part of the results of gemfibrozil and non-gemfibrozil fibrate trials
Mass changes in remnant cholesterol and LDL cholesterol explain part of the results of gemfibrozil and non-gemfibrozil fibrate trials
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Mass changes in remnant cholesterol and LDL cholesterol explain part of the results of gemfibrozil and non-gemfibrozil fibrate trials

Doi, Takahito ; Langsted, Anne ; Nordestgaard, Børge G

Journal of internal medicine, 2024-05, Vol.295 (5), p.707-710 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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3
Gemfibrozil derivatives as activators of soluble guanylyl cyclase – A structure-activity study
Gemfibrozil derivatives as activators of soluble guanylyl cyclase – A structure-activity study
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Gemfibrozil derivatives as activators of soluble guanylyl cyclase – A structure-activity study

Gayler, Kevin M. ; Quintana, Jeremy M. ; Mattke, Jordan ; Plunk, Michael A. ; Kostyo, Jessica H. ; Karunananthan, Johann W. ; Nguyen, Harold ; Shuda, Mina ; Ferreira, Liam D. ; Baker, Hannah ; Stinchcomb, Alexandra L. ; Sharina, Iraida ; Kane, Robert R. ; Martin, Emil

European journal of medicinal chemistry, 2021-11, Vol.224, p.113729-113729, Article 113729 [Periódico revisado por pares]

France: Elsevier Masson SAS

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4
Gemfibrozil May Decrease Norclozapine Elimination: A Case Report
Gemfibrozil May Decrease Norclozapine Elimination: A Case Report
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Gemfibrozil May Decrease Norclozapine Elimination: A Case Report

Barclay, Jaqueline ; McCollum, Betsy ; Schoretsanitis, Georgios ; de Leon, Jose

Journal of clinical psychopharmacology, 2019-07, Vol.39 (4), p.405-407 [Periódico revisado por pares]

United States

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5
Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug–Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil
Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug–Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil
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Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug–Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil

Iga, Katsumi ; Kiriyama, Akiko

Clinical pharmacokinetics, 2024, Vol.63 (1), p.43-56 [Periódico revisado por pares]

Cham: Springer International Publishing

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6
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo
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Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo

Song, Xue-Qing ; Guo, Xu ; Ding, Yi-Xin ; Han, Yi-Xuan ; You, Zhi-Hao ; Song, Yali ; Yuan, Yanan ; Li, Longfei

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7033-7047 [Periódico revisado por pares]

United States: American Chemical Society

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7
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging
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Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging

Hakimizadeh, Elham ; Tadayon, Saeedeh ; Zamanian, Mohammad Yasin ; Soltani, Afsaneh ; Giménez‐Llort, Lydia ; Hassanipour, Mahsa ; Fatemi, Iman

Fundamental & clinical pharmacology, 2023-06, Vol.37 (3), p.599-605 [Periódico revisado por pares]

England: Wiley Subscription Services, Inc

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8
Association of plasma metabolites and diagnostic imaging findings with hepatic lipidosis in bearded dragons (Pogona vitticeps) and effects of gemfibrozil therapy
Association of plasma metabolites and diagnostic imaging findings with hepatic lipidosis in bearded dragons (Pogona vitticeps) and effects of gemfibrozil therapy
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Association of plasma metabolites and diagnostic imaging findings with hepatic lipidosis in bearded dragons (Pogona vitticeps) and effects of gemfibrozil therapy

Barboza, Trinita K ; Susta, Leonardo ; Zur Linden, Alex ; Gardhouse, Sara ; Beaufrère, Hugues Takahashi, Nobuyuki

PloS one, 2023-02, Vol.18 (2), p.e0274060-e0274060 [Periódico revisado por pares]

United States: Public Library of Science

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9
Gemfibrozil improves lipid metabolism in Nile tilapia Oreochromis niloticus fed a high-carbohydrate diet through peroxisome proliferator activated receptor-α activation
Gemfibrozil improves lipid metabolism in Nile tilapia Oreochromis niloticus fed a high-carbohydrate diet through peroxisome proliferator activated receptor-α activation
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Gemfibrozil improves lipid metabolism in Nile tilapia Oreochromis niloticus fed a high-carbohydrate diet through peroxisome proliferator activated receptor-α activation

Luo, Yuan ; Hu, Chun-Ting ; Qiao, Fang ; Wang, Xiao-Dan ; Qin, Jian G. ; Du, Zhen-Yu ; Chen, Li-Qiao

General and comparative endocrinology, 2020-09, Vol.296, p.113537, Article 113537 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil
Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil
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Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil

Shitara, Yoshihisa ; Hirano, Masaru ; Sato, Hitoshi ; Sugiyama, Yuichi

The Journal of pharmacology and experimental therapeutics, 2004-10, Vol.311 (1), p.228-236 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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