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Strategies and challenges for the next generation of antibody-drug conjugates
Strategies and challenges for the next generation of antibody-drug conjugates
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Strategies and challenges for the next generation of antibody-drug conjugates

Beck, Alain ; Goetsch, Liliane ; Dumontet, Charles ; Corvaïa, Nathalie

Nature reviews. Drug discovery, 2017-05, Vol.16 (5), p.315-337 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Antitumor Activity and Safety of Trastuzumab Deruxtecan in Patients With HER2-Low-Expressing Advanced Breast Cancer: Results From a Phase Ib Study
Antitumor Activity and Safety of Trastuzumab Deruxtecan in Patients With HER2-Low-Expressing Advanced Breast Cancer: Results From a Phase Ib Study
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Antitumor Activity and Safety of Trastuzumab Deruxtecan in Patients With HER2-Low-Expressing Advanced Breast Cancer: Results From a Phase Ib Study

Modi, Shanu ; Park, Haeseong ; Murthy, Rashmi K ; Iwata, Hiroji ; Tamura, Kenji ; Tsurutani, Junji ; Moreno-Aspitia, Alvaro ; Doi, Toshihiko ; Sagara, Yasuaki ; Redfern, Charles ; Krop, Ian E ; Lee, Caleb ; Fujisaki, Yoshihiko ; Sugihara, Masahiro ; Zhang, Lin ; Shahidi, Javad ; Takahashi, Shunji

Journal of clinical oncology, 2020-06, Vol.38 (17), p.1887-1896 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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3
Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer
Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer
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Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer

Modi, Shanu ; Jacot, William ; Yamashita, Toshinari ; Sohn, Joohyuk ; Vidal, Maria ; Tokunaga, Eriko ; Tsurutani, Junji ; Ueno, Naoto T. ; Prat, Aleix ; Chae, Yee Soo ; Lee, Keun Seok ; Niikura, Naoki ; Park, Yeon Hee ; Xu, Binghe ; Wang, Xiaojia ; Gil-Gil, Miguel ; Li, Wei ; Pierga, Jean-Yves ; Im, Seock-Ah ; Moore, Halle C.F. ; Rugo, Hope S. ; Yerushalmi, Rinat ; Zagouri, Flora ; Gombos, Andrea ; Kim, Sung-Bae ; Liu, Qiang ; Luo, Ting ; Saura, Cristina ; Schmid, Peter ; Sun, Tao ; Gambhire, Dhiraj ; Yung, Lotus ; Wang, Yibin ; Singh, Jasmeet ; Vitazka, Patrik ; Meinhardt, Gerold ; Harbeck, Nadia ; Cameron, David A.

The New England journal of medicine, 2022-07, Vol.387 (1), p.9-20 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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4
DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1
DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1
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DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1

Ogitani, Yusuke ; Aida, Tetsuo ; Hagihara, Katsunobu ; Yamaguchi, Junko ; Ishii, Chiaki ; Harada, Naoya ; Soma, Masako ; Okamoto, Hiromi ; Oitate, Masataka ; Arakawa, Shingo ; Hirai, Takehiro ; Atsumi, Ryo ; Nakada, Takashi ; Hayakawa, Ichiro ; Abe, Yuki ; Agatsuma, Toshinori

Clinical cancer research, 2016-10, Vol.22 (20), p.5097-5108 [Periódico revisado por pares]

United States

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5
Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma
Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma
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Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma

Tilly, Hervé ; Morschhauser, Franck ; Sehn, Laurie H ; Friedberg, Jonathan W ; Trněný, Marek ; Sharman, Jeff P ; Herbaux, Charles ; Burke, John M ; Matasar, Matthew ; Rai, Shinya ; Izutsu, Koji ; Mehta-Shah, Neha ; Oberic, Lucie ; Chauchet, Adrien ; Jurczak, Wojciech ; Song, Yuqin ; Greil, Richard ; Mykhalska, Larysa ; Bergua-Burgués, Juan M ; Cheung, Matthew C ; Pinto, Antonio ; Shin, Ho-Jin ; Hapgood, Greg ; Munhoz, Eduardo ; Abrisqueta, Pau ; Gau, Jyh-Pyng ; Hirata, Jamie ; Jiang, Yanwen ; Yan, Mark ; Lee, Calvin ; Flowers, Christopher R ; Salles, Gilles

The New England journal of medicine, 2022-01, Vol.386 (4), p.351-363 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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6
Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer
Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer
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Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer

Cortés, Javier ; Kim, Sung-Bae ; Chung, Wei-Pang ; Im, Seock-Ah ; Park, Yeon Hee ; Hegg, Roberto ; Kim, Min Hwan ; Tseng, Ling-Ming ; Petry, Vanessa ; Chung, Chi-Feng ; Iwata, Hiroji ; Hamilton, Erika ; Curigliano, Giuseppe ; Xu, Binghe ; Huang, Chiun-Sheng ; Kim, Jee Hyun ; Chiu, Joanne W.Y ; Pedrini, Jose Luiz ; Lee, Caleb ; Liu, Yali ; Cathcart, Jillian ; Bako, Emarjola ; Verma, Sunil ; Hurvitz, Sara A

The New England journal of medicine, 2022-03, Vol.386 (12), p.1143-1154 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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7
Antibody Drug Conjugates for Cancer Therapy
Antibody Drug Conjugates for Cancer Therapy
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Antibody Drug Conjugates for Cancer Therapy

Polakis, Paul Esbenshade, Timothy A.

Pharmacological reviews, 2016-01, Vol.68 (1), p.3-19 [Periódico revisado por pares]

United States

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8
Polatuzumab Vedotin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Polatuzumab Vedotin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma
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Polatuzumab Vedotin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Sehn, Laurie H ; Herrera, Alex F ; Flowers, Christopher R ; Kamdar, Manali K ; McMillan, Andrew ; Hertzberg, Mark ; Assouline, Sarit ; Kim, Tae Min ; Kim, Won Seog ; Ozcan, Muhit ; Hirata, Jamie ; Penuel, Elicia ; Paulson, Joseph N ; Cheng, Ji ; Ku, Grace ; Matasar, Matthew J

Journal of clinical oncology, 2020-01, Vol.38 (2), p.155-165 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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9
Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
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Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer

Bardia, Aditya ; Hurvitz, Sara A ; Tolaney, Sara M ; Loirat, Delphine ; Punie, Kevin ; Oliveira, Mafalda ; Brufsky, Adam ; Sardesai, Sagar D ; Kalinsky, Kevin ; Zelnak, Amelia B ; Weaver, Robert ; Traina, Tiffany ; Dalenc, Florence ; Aftimos, Philippe ; Lynce, Filipa ; Diab, Sami ; Cortés, Javier ; O’Shaughnessy, Joyce ; Diéras, Véronique ; Ferrario, Cristiano ; Schmid, Peter ; Carey, Lisa A ; Gianni, Luca ; Piccart, Martine J ; Loibl, Sibylle ; Goldenberg, David M ; Hong, Quan ; Olivo, Martin S ; Itri, Loretta M ; Rugo, Hope S

The New England journal of medicine, 2021-04, Vol.384 (16), p.1529-1541 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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10
TROPHY-U-01: A Phase II Open-Label Study of Sacituzumab Govitecan in Patients With Metastatic Urothelial Carcinoma Progressing After Platinum-Based Chemotherapy and Checkpoint Inhibitors
TROPHY-U-01: A Phase II Open-Label Study of Sacituzumab Govitecan in Patients With Metastatic Urothelial Carcinoma Progressing After Platinum-Based Chemotherapy and Checkpoint Inhibitors
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TROPHY-U-01: A Phase II Open-Label Study of Sacituzumab Govitecan in Patients With Metastatic Urothelial Carcinoma Progressing After Platinum-Based Chemotherapy and Checkpoint Inhibitors

Tagawa, Scott T ; Balar, Arjun V ; Petrylak, Daniel P ; Kalebasty, Arash Rezazadeh ; Loriot, Yohann ; Fléchon, Aude ; Jain, Rohit K ; Agarwal, Neeraj ; Bupathi, Manojkumar ; Barthelemy, Philippe ; Beuzeboc, Philippe ; Palmbos, Phillip ; Kyriakopoulos, Christos E ; Pouessel, Damien ; Sternberg, Cora N ; Hong, Quan ; Goswami, Trishna ; Itri, Loretta M ; Grivas, Petros

Journal of clinical oncology, 2021-08, Vol.39 (22), p.2474-2485 [Periódico revisado por pares]

United States: Wolters Kluwer Health

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