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Material Type: Artigo
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High interstitial fluid pressure - an obstacle in cancer therapyHeldin, Carl-Henrik ; Rubin, Kristofer ; Pietras, Kristian ; Östman, ArneNature reviews. Cancer, 2004-10, Vol.4 (10), p.806-813 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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2 |
Material Type: Artigo
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Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivoYang, Yue ; Mohammed, Farheen Sultana ; Zhang, Ning ; Sauve, Anthony A.The Journal of biological chemistry, 2019-06, Vol.294 (23), p.9295-9307 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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3 |
Material Type: Artigo
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Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult OffspringEar, Po Hien ; Chadda, Ankita ; Gumusoglu, Serena B. ; Schmidt, Mark S. ; Vogeler, Sophia ; Malicoat, Johnny ; Kadel, Jacob ; Moore, Michelle M. ; Migaud, Marie E. ; Stevens, Hanna E. ; Brenner, CharlesCell reports (Cambridge), 2019-01, Vol.26 (4), p.969-983.e4 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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NAD+ supplementation rejuvenates aged gut adult stem cellsIgarashi, Masaki ; Miura, Masaomi ; Williams, Eric ; Jaksch, Frank ; Kadowaki, Takashi ; Yamauchi, Toshimasa ; Guarente, LeonardAging cell, 2019-06, Vol.18 (3), p.e12935-n/a [Periódico revisado por pares]England: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s diseaseBrakedal, Brage ; Dölle, Christian ; Riemer, Frank ; Ma, Yilong ; Nido, Gonzalo S. ; Skeie, Geir Olve ; Craven, Alexander R. ; Schwarzlmüller, Thomas ; Brekke, Njål ; Diab, Joseph ; Sverkeli, Lars ; Skjeie, Vivian ; Varhaug, Kristin ; Tysnes, Ole-Bjørn ; Peng, Shichun ; Haugarvoll, Kristoffer ; Ziegler, Mathias ; Grüner, Renate ; Eidelberg, David ; Tzoulis, CharalamposCell metabolism, 2022-03, Vol.34 (3), p.396-407.e6 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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6 |
Material Type: Artigo
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Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal MuscleFrederick, David W. ; Loro, Emanuele ; Liu, Ling ; Davila, Antonio ; Chellappa, Karthikeyani ; Silverman, Ian M. ; Quinn, William J. ; Gosai, Sager J. ; Tichy, Elisia D. ; Davis, James G. ; Mourkioti, Foteini ; Gregory, Brian D. ; Dellinger, Ryan W. ; Redpath, Philip ; Migaud, Marie E. ; Nakamaru-Ogiso, Eiko ; Rabinowitz, Joshua D. ; Khurana, Tejvir S. ; Baur, Joseph A.Cell metabolism, 2016-08, Vol.24 (2), p.269-282 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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7 |
Material Type: Artigo
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Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metforminDeWaal, Dannielle ; Nogueira, Veronique ; Terry, Alexander R ; Patra, Krushna C ; Jeon, Sang-Min ; Guzman, Grace ; Au, Jennifer ; Long, Christopher P ; Antoniewicz, Maciek R ; Hay, NissimNature communications, 2018-01, Vol.9 (1), p.446-14, Article 446 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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8 |
Material Type: Artigo
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Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged miceWilliams, Pete A ; Harder, Jeffrey M ; Foxworth, Nicole E ; Cochran, Kelly E ; Philip, Vivek M ; Porciatti, Vittorio ; Smithies, Oliver ; John, Simon W MScience (American Association for the Advancement of Science), 2017-02, Vol.355 (6326), p.756-760 [Periódico revisado por pares]United StatesTexto completo disponível |
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9 |
Material Type: Artigo
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The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1Wylie, Andrew A ; Schoepfer, Joseph ; Jahnke, Wolfgang ; Cowan-Jacob, Sandra W ; Loo, Alice ; Furet, Pascal ; Marzinzik, Andreas L ; Pelle, Xavier ; Donovan, Jerry ; Zhu, Wenjing ; Buonamici, Silvia ; Hassan, A Quamrul ; Lombardo, Franco ; Iyer, Varsha ; Palmer, Michael ; Berellini, Giuliano ; Dodd, Stephanie ; Thohan, Sanjeev ; Bitter, Hans ; Branford, Susan ; Ross, David M ; Hughes, Timothy P ; Petruzzelli, Lilli ; Vanasse, K Gary ; Warmuth, Markus ; Hofmann, Francesco ; Keen, Nicholas J ; Sellers, William RNature (London), 2017-03, Vol.543 (7647), p.733-737 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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10 |
Material Type: Artigo
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Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 MutantsEide, Christopher A. ; Zabriskie, Matthew S. ; Savage Stevens, Samantha L. ; Antelope, Orlando ; Vellore, Nadeem A. ; Than, Hein ; Schultz, Anna Reister ; Clair, Phillip ; Bowler, Amber D. ; Pomicter, Anthony D. ; Yan, Dongqing ; Senina, Anna V. ; Qiang, Wang ; Kelley, Todd W. ; Szankasi, Philippe ; Heinrich, Michael C. ; Tyner, Jeffrey W. ; Rea, Delphine ; Cayuela, Jean-Michel ; Kim, Dong-Wook ; Tognon, Cristina E. ; O'Hare, Thomas ; Druker, Brian J. ; Deininger, Michael W.Cancer cell, 2019-10, Vol.36 (4), p.431-443.e5 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |