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Material Type: Artigo
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Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal TransducersMurphy, Michael P. ; O’Neill, Luke A.J.Cell, 2018-08, Vol.174 (4), p.780-784 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian CellsHosios, Aaron M. ; Hecht, Vivian C. ; Danai, Laura V. ; Johnson, Marc O. ; Rathmell, Jeffrey C. ; Steinhauser, Matthew L. ; Manalis, Scott R. ; Vander Heiden, Matthew G.Developmental cell, 2016-03, Vol.36 (5), p.540-549 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Regulation and function of the mammalian tricarboxylic acid cycleArnold, Paige K. ; Finley, Lydia W.S.The Journal of biological chemistry, 2023-02, Vol.299 (2), p.102838-102838, Article 102838 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Hypoxia-Mediated Increases in l-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive StressOldham, William M. ; Clish, Clary B. ; Yang, Yi ; Loscalzo, JosephCell metabolism, 2015-08, Vol.22 (2), p.291-303 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in CancerStacpoole, Peter WJNCI : Journal of the National Cancer Institute, 2017-11, Vol.109 (11) [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate LyaseLauterbach, Mario A. ; Hanke, Jasmin E. ; Serefidou, Magdalini ; Mangan, Matthew S.J. ; Kolbe, Carl-Christian ; Hess, Timo ; Rothe, Maximilian ; Kaiser, Romina ; Hoss, Florian ; Gehlen, Jan ; Engels, Gudrun ; Kreutzenbeck, Maike ; Schmidt, Susanne V. ; Christ, Anette ; Imhof, Axel ; Hiller, Karsten ; Latz, EickeImmunity (Cambridge, Mass.), 2019-12, Vol.51 (6), p.997-1011.e7 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Slow TCA flux and ATP production in primary solid tumours but not metastasesBartman, Caroline R ; Weilandt, Daniel R ; Shen, Yihui ; Lee, Won Dong ; Han, Yujiao ; TeSlaa, Tara ; Jankowski, Connor S R ; Samarah, Laith ; Park, Noel R ; da Silva-Diz, Victoria ; Aleksandrova, Maya ; Gultekin, Yetis ; Marishta, Argit ; Wang, Lin ; Yang, Lifeng ; Roichman, Asael ; Bhatt, Vrushank ; Lan, Taijin ; Hu, Zhixian ; Xing, Xi ; Lu, Wenyun ; Davidson, Shawn ; Wühr, Martin ; Vander Heiden, Matthew G ; Herranz, Daniel ; Guo, Jessie Yanxiang ; Kang, Yibin ; Rabinowitz, Joshua DNature (London), 2023-02, Vol.614 (7947), p.349-357 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell ProliferationLunt, Sophia Y ; Vander Heiden, Matthew GAnnual review of cell and developmental biology, 2011-01, Vol.27 (1), p.441-464 [Periódico revisado por pares]United States: Annual ReviewsTexto completo disponível |
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Material Type: Artigo
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Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B CellsLe, Anne ; Lane, Andrew N. ; Hamaker, Max ; Bose, Sminu ; Gouw, Arvin ; Barbi, Joseph ; Tsukamoto, Takashi ; Rojas, Camilio J. ; Slusher, Barbara S. ; Zhang, Haixia ; Zimmerman, Lisa J. ; Liebler, Daniel C. ; Slebos, Robbert J.C. ; Lorkiewicz, Pawel K. ; Higashi, Richard M. ; Fan, Teresa W.M. ; Dang, Chi V.Cell metabolism, 2012-01, Vol.15 (1), p.110-121 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacidsStubbs, R Trent ; Yadav, Mahipal ; Krishnamurthy, Ramanarayanan ; Springsteen, GregNature chemistry, 2020-11, Vol.12 (11), p.1016-1022 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |