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1
Material Type:
Livro
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The biochemistry of folic acid and related pteridines

Raymond L. Blakley 1926-

Amsterdam London North-Holland Publishing Co. 1969

Localização: CQ - Conjunto das Químicas    (574.19296 B637b )(Acessar)

2
An introduction to the chemistry and biochemistry of pyrimidines, purines, and pteridines
Material Type:
Livro
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An introduction to the chemistry and biochemistry of pyrimidines, purines, and pteridines

Derek T. Hurst

Chichester Eng. New York J. Wiley c1980

Localização: CQ - Conjunto das Químicas    (547.593 H966i )(Acessar)

3
Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy
Material Type:
Artigo
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Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy

Döhner, Hartmut ; Lübbert, Michael ; Fiedler, Walter ; Fouillard, Loic ; Haaland, Alf ; Brandwein, Joseph M. ; Lepretre, Stephane ; Reman, Oumedaly ; Turlure, Pascal ; Ottmann, Oliver G. ; Müller-Tidow, Carsten ; Krämer, Alwin ; Raffoux, Emmanuel ; Döhner, Konstanze ; Schlenk, Richard F. ; Voss, Florian ; Taube, Tillmann ; Fritsch, Holger ; Maertens, Johan

Blood, 2014-08, Vol.124 (9), p.1426-1433 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors
Material Type:
Artigo
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Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors

Wang, Ning-Yu ; Xu, Ying ; Xiao, Kun-Jie ; Zuo, Wei-Qiong ; Zhu, Yong-Xia ; Hu, Rong ; Wang, Wan-Li ; Shi, Yao-Jie ; Yu, Luo-Ting ; Liu, Zhi-Hao

European journal of medicinal chemistry, 2020-04, Vol.191, p.112152, Article 112152 [Periódico revisado por pares]

France: Elsevier Masson SAS

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5
Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis
Material Type:
Artigo
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Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis

Roethle, Paul A ; McFadden, Ryan M ; Yang, Hong ; Hrvatin, Paul ; Hui, Hon ; Graupe, Michael ; Gallagher, Brian ; Chao, Jessica ; Hesselgesser, Joseph ; Duatschek, Paul ; Zheng, Jim ; Lu, Bing ; Tumas, Daniel B ; Perry, Jason ; Halcomb, Randall L

Journal of medicinal chemistry, 2013-09, Vol.56 (18), p.7324-7333 [Periódico revisado por pares]

United States: American Chemical Society

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6
A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma
Material Type:
Artigo
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A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

Wu, Mengjiao ; Wang, Yan ; Yang, Di ; Gong, Ying ; Rao, Feng ; Liu, Rui ; Danna, Yeerken ; Li, Jinting ; Fan, Jiawen ; Chen, Jie ; Zhang, Weimin ; Zhan, Qimin

EBioMedicine, 2019-03, Vol.41, p.244-255 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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7
A phase I study of two dosing schedules of volasertib (BI 6727), an intravenous polo-like kinase inhibitor, in patients with advanced solid malignancies
Material Type:
Artigo
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A phase I study of two dosing schedules of volasertib (BI 6727), an intravenous polo-like kinase inhibitor, in patients with advanced solid malignancies

LIN, C.-C ; SU, W.-C ; VOSS, F ; TAUBE, T ; YANG, J. C.H ; YEN, C.-J ; HSU, C.-H ; SU, W.-P ; YEH, K.-H ; LU, Y.-S ; CHENG, A.-L ; HUANG, D. C.L ; FRITSCH, H

British journal of cancer, 2014-05, Vol.110 (10), p.2434-2440 [Periódico revisado por pares]

Basingstoke: Nature Publishing Group

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8
Current clinical trials with polo-like kinase 1 inhibitors in solid tumors
Material Type:
Artigo
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Current clinical trials with polo-like kinase 1 inhibitors in solid tumors

Yim, Hyungshin

Anti-cancer drugs, 2013-11, Vol.24 (10), p.999-1006 [Periódico revisado por pares]

England: Wolters Kluwer Health | Lippincott Williams & Wilkins

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9
Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor
Material Type:
Artigo
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Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor

Van den Bossche, J. ; Lardon, F. ; Deschoolmeester, V. ; De Pauw, I. ; Vermorken, J.B. ; Specenier, P. ; Pauwels, P. ; Peeters, M. ; Wouters, A.

Medicinal research reviews, 2016-07, Vol.36 (4), p.749-786 [Periódico revisado por pares]

United States: Blackwell Publishing Ltd

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10
GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees
Material Type:
Artigo
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GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees

Lanford, Robert E ; Guerra, Bernadette ; Chavez, Deborah ; Giavedoni, Luis ; Hodara, Vida L ; Brasky, Kathleen M ; Fosdick, Abigail ; Frey, Christian R ; Zheng, Jim ; Wolfgang, Grushenka ; Halcomb, Randall L ; Tumas, Daniel B

Gastroenterology (New York, N.Y. 1943), 2013-06, Vol.144 (7), p.1508-1517.e10 [Periódico revisado por pares]

United States: Elsevier Inc

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