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Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes
Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes
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Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes

Wang, Yundi ; Eldstrom, Jodene ; Fedida, David

Frontiers in physiology, 2020-06, Vol.11, p.504-504 [Periódico revisado por pares]

Frontiers Research Foundation

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2
A novel ion conducting route besides the central pore in an inherited mutant of G‐protein‐gated inwardly rectifying K+ channel
A novel ion conducting route besides the central pore in an inherited mutant of G‐protein‐gated inwardly rectifying K+ channel
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A novel ion conducting route besides the central pore in an inherited mutant of G‐protein‐gated inwardly rectifying K+ channel

Chen, I‐Shan ; Eldstrom, Jodene ; Fedida, David ; Kubo, Yoshihiro

The Journal of physiology, 2022-02, Vol.600 (3), p.603-622 [Periódico revisado por pares]

England: Wiley Subscription Services, Inc

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3
Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277
Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277
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Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277

Willegems, Katrien ; Eldstrom, Jodene ; Kyriakis, Efthimios ; Ataei, Fariba ; Sahakyan, Harutyun ; Dou, Ying ; Russo, Sophia ; Van Petegem, Filip ; Fedida, David

Nature communications, 2022-06, Vol.13 (1), p.3760-3760, Article 3760 [Periódico revisado por pares]

London: Nature Publishing Group

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4
Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening
Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening
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Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

Hou, Panpan ; Eldstrom, Jodene ; Shi, Jingyi ; Zhong, Ling ; McFarland, Kelli ; Gao, Yuan ; Fedida, David ; Cui, Jianmin

Nature communications, 2017-11, Vol.8 (1), p.1730-11, Article 1730 [Periódico revisado por pares]

England: Nature Publishing Group

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5
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
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A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

Chan, Magnus ; Sahakyan, Harutyun ; Eldstrom, Jodene ; Sastre, Daniel ; Wang, Yundi ; Dou, Ying ; Pourrier, Marc ; Vardanyan, Vitya ; Fedida, David

eLife, 2023-09, Vol.12 [Periódico revisado por pares]

Cambridge: eLife Sciences Publications Ltd

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6
Single-channel basis for the slow activation of the repolarizing cardiac potassium current, IKs
Single-channel basis for the slow activation of the repolarizing cardiac potassium current, IKs
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Single-channel basis for the slow activation of the repolarizing cardiac potassium current, IKs

Werry, Daniel ; Eldstrom, Jodene ; Wang, Zhuren ; Fedida, David

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (11), p.E996-E1005 [Periódico revisado por pares]

National Acad Sciences

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7
cAMP-dependent regulation of IKs single-channel kinetics
cAMP-dependent regulation of IKs single-channel kinetics
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cAMP-dependent regulation of IKs single-channel kinetics

Thompson, Emely ; Eldstrom, Jodene ; Westhoff, Maartje ; McAfee, Donald ; Balse, Elise ; Fedida, David

The Journal of general physiology, 2017-08, Vol.149 (8), p.781-798 [Periódico revisado por pares]

Rockefeller University Press

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8
The I Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry
The I Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry
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The I Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry

Thompson, Emely ; Eldstrom, Jodene ; Westhoff, Maartje ; McAfee, Donald ; Fedida, David

Biophysical journal, 2018-11, Vol.115 (9), p.1731-1740 [Periódico revisado por pares]

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9
Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4
Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4
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Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4

Murray, Christopher I ; Westhoff, Maartje ; Eldstrom, Jodene ; Thompson, Emely ; Emes, Robert ; Fedida, David

eLife, 2016-01, Vol.5 [Periódico revisado por pares]

England: eLife Sciences Publications Ltd

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10
The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome
The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome
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The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome

Eldstrom, Jodene ; Fedida, David

Expert reviews in molecular medicine, 2011-12, Vol.13, p.e38-e38, Article e38 [Periódico revisado por pares]

Cambridge, UK: Cambridge University Press

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